Electron microscopic observations and DNA chain fragmentation studies on apoptosis in bone tumor cells induced by ~(153)Sm-EDTMP

ＥｌｅｃｔｒｏｎｍｉｃｒｏｓｃｏｐｉｃｏｂｓｅｒｖａｔｉｏｎｓａｎｄＤＮＡｃｈａｉｎｆｒａｇｍｅｎｔａｔｉｏｎｓｔｕｄｉｅｓｏｎａｐｏｐｔｏｓｉｓｉｎｂｏｎｅｔｕｍｏｒｃｅｌｓｉｎｄｕｃｅｄｂｙ１５３ＳｍＥＤＴＭＰＺｈｕＳｈｏｕＰｅｎｇ，Ｘｉａ...     

Trace elements in human transitory milk. Variation caused by biological attributes of mother and infant

Multielement analysis was performed on human milk collected on 5-9-d postpartum from 51 Japanese females using inductively coupled plasma (ICP) mass spectrometry (MS), ICP atomic emission spectrometry (ICP-AES) and fluorometry. Thirty-one elements were detected by these analytical methods in milk. Twelve elements (Na, Mg, P, S, K, Ca, Cu, Zn, Se, Sr, Rb, and Mo) were detected in all of the samples. Al, Cs, and Ba were the elements detected by ICP-MS in more than half of the samples. Multiple regression analysis extracted biological attributes of mother and infant, such as maternal stature, maternal wt, or infant's birth wt, as statistically significant factors contributing to the variation in elemental concentration in milk. However, the rates of contribution were small in all cases. It was concluded that the biological attributes of mother and infant examined in this study were not the major factors that contribute to elemental variation in human milk.     

Up-regulation of CIR1/CROC1 expression upon cell immortalization and in tumor-derived human cell lines

Inactivation of 5-HT1A and [3H]5-HT binding sites by N-Ethoxycarbonyl-2-ethoxy-1, 2-dihydroquinoline (EEDQ) was studied in regions of rat brain. After exposure to EEDQ (4 mg/kg body wt.) for 7 days, it is observed that the density of 5-HT1 receptor sites was decreased by nearly 20% in both cortex and hippocampus. The decrease, however, in 5-HT1A sites was more significant (70%) in both the regions. The affinity of [3H]5-HT to 5-HT1 sites was decreased significantly in both cortex and hippocampus after exposure to EEDQ, without affecting the Kd of 5-HT1A sites. Displacement studies suggested that EEDQ has high affinity to 5-HT1 sites with a Ki of 42.9+/-2.4 nM. After exposure neither basal nor 5-HT stimulated adenylyl cyclase activity was changed in cortex. The results of this study suggest that EEDQ decreases the density of 5-HT1 and 5-HT1A receptor sites but does not cause functional downregulation of these sites in rat brain.     

布尔函数的对偶性和线性点

本文主要讨论了部分自对偶和部分反自对偶函数、部分线性函数以及具有线性点的函数的性质。     

Finite element analysis of local damage and post-failure behavior for strain-softening solid

A finite element analysis of the viscoplastic-softening model with the evolution of local damage for strain softening material is presented. An effective damage matrix is introduced to consider the influence of isotropic damage on different types of micro-cracking by different states of stress. The localized strain mode with local damage occurs in the post-failure regime of deformation. The computational techniques for tracing the post-failure path of the softening response are discussed with several examples.     

Efficient Skyline and Top-k Retrieval in Subspaces

Skyline and top-k queries are two popular operations for preference retrieval. In practice, applications that require these operations usually provide numerous candidate attributes, whereas, depending on their interests, users may issue queries regarding different subsets of the dimensions. The existing algorithms are inadequate for subspace skyline/top-k search because they have at least one of the following defects: 1) they require scanning the entire database at least once, 2) they are optimized for one subspace but incur significant overhead for other subspaces, or 3) they demand expensive maintenance cost or space consumption. In this paper, we propose a technique SUBSKY, which settles both types of queries by using purely relational technologies. The core of SUBSKY is a transformation that converts multidimensional data to one-dimensional (1D) values. These values are indexed by a simple B-tree, which allows us to answer subspace queries by accessing a fraction of the database. SUBSKY entails low maintenance overhead, which equals the cost of updating a traditional B-tree. Extensive experiments with real data confirm that our technique outperforms alternative solutions significantly in both efficiency and scalability.     

CFCA与各商业银行建立"网银反欺诈联动机制"

近日,“网上银行反欺诈联动机制”联合声明暨“2007放心安全用网银联合宣传年”启动新闻发布会在北京召开,此次会议由“放心安全用网银联合宣传年”活动组委会主办。“放心安全用网银联合宣传年”活动是     

双能X射线骨密度仪测定技术研究

以Ｌｕｎａｒ公司ＤＰＸ－Ｌ型双能Ｘ射线骨密度仪为例，研究引起测量误差的主要因素并提出质控措施。用自检模块、腰椎体膜评定仪器的体外测量精度好于１％。对１０位志愿者重复２次测量，体内精度对腰椎，ＭＰＤ（平均百分差）为０．４６，ＣＶ（变异系数）为０．７５；对股骨颈，ＭＰＤ为１．２６、ＣＶ为０．４７；Ｗａｒｄ’ｓ三角区ＭＰＤ为２．０１、ＣＶ为１．１４；大转子ＭＰＤ为１．６６、ＣＶ为０．７２。扫描图像由２位