A mixed-integer programming approach for solving university course timetabling problems

Journal of Scheduling - This article presents a mixed-integer programming model for solving the university timetabling problem which considers the allocation of students to classes and the...     

Ceramide structure of sphingomyelin from human milk fat globule membrane

Sphingomyelin was purified from human milk fat globule membrane and submitted to phospholipase C to yield ceramide. The structure of this ceramide was investigated by gas liquid chromatographic analyses of its components, fatty acids and sphingoid bases. The structure of the native ceramide was confirmed by direct-inlet mass spectrometry. It was shown to contain a major base C₁₈-sphingosine associated with a high proportion (60%) of C₂₀, C₂₂, C₂₄ and C_24∶1 nonhydroxylated fatty acids. As these very long-chain fatty acids might be of nutritive importance, the concentration of sphingomyelin in human milk and its distribution in cream and skim milk were established.     

Mechanical behaviour of pre-stressed spruce timber–timber 2.5-mm-step grooved connections under shearing tests

A smart shear connection system was tested in order to be used in manufactured elements of a lattice of wooden slats and a cross offset. This type of floor element can present advantages both in terms of weight and suitable insulating filler (Adalberth et al. 2001; Kawasaki and Kawai 2006; Kermani and Hairstans 2006; Dodoo et al. 2014). This connection is made to provide a substitute for a glue connection. The shear connection proposed is made by double-sided grooving timber interfaces to form a cross section. A specifically designed test assembly was constructed to measure and guarantee homogeneous contact pressure in interface test specimens. Shear test results are presented and compared in terms of capacity and stiffness with glue connections. The principal conclusions are as follows: the allowable shearing resistance of the grooved timber–timber joints can approximately reach the resistance of glued connections. The stiffness of the joints is improved by increasing the pre-stress applied for holding contact in the assembly. The grooved timber-to-timber joints exhibit non-linear behaviour which dominates the behaviour of the whole system. Therefore, the behaviour of a unit connection must be determined to obtain the mean load-carrying capacity and stiffness of a system with grooved connections.     

Zn(1-x)MnxTe diluted magnetic semiconductor nanowires grown by molecular beam epitaxy

It is shown that the growth of II-VI diluted magnetic semiconductor nanowires is possible by the catalytically enhanced molecular beam epitaxy (MBE). Zn(1-x)MnxTe NWs with manganese content up to x=0.60 were produced by this method. X-ray diffraction, Raman spectroscopy, and temperature dependent photoluminescence measurements confirm the incorporation of Mn(2+) ions in the cation substitutional sites of the ZnTe matrix of the NWs.     

Nonlinear Observer-Based Feedback for Open-Channel Level Control

This paper is devoted to nonlinear observer and controller design for water level control of open-channel flow in irrigation canals or dam-river systems. A finite-dimensional model, previously developed by orthogonal collocation methods, based on Saint Venant equations and used for control design, is now further used for online flow rate and water infiltration estimation. This is done by a so-called state observer. In particular, the estimates obtained in this way can successfully be used in a controller previously proposed, resulting in a water level control law using only two level measurements along the canal (instead of the four measurements previously needed). The study is restricted to the case of a rectangular wetted section and subcritical flow. The results have been validated by simulations, on an implicit finite difference simulator based on a Preissmann scheme for various scenarios.     

Gender and education impact on brain aging: A general cognitive factor approach.

In cognitive aging research, the study of a general cognitive factor has been shown to have a substantial explanatory power over the study of isolated tests. The authors aimed at differentiating the impact of gender and education on global cognitive change with age from their differential impact on 4 psychometric tests using a new latent process approach, which intermediates between a single-factor longitudinal model for sum scores and an item-response theory approach for longitudinal data. The analysis was conducted on a sample of 2,228 subjects from PAQUID, a population-based cohort of older adults followed for 13 years with repeated measures of cognition. Adjusted for vascular factors, the analysis confirmed that women performed better in tests involving verbal components, while men performed better in tests involving visuospatial skills. In addition, the model suggested that women had a slightly steeper global cognitive decline with oldest age than men, even after excluding incident dementia or death. Subjects with higher education exhibited a better mean score for the 4 tests, but this difference tended to attenuate with age for tests involving a speed component. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The theoretical rationale for a multinationality-performance relationship

Abstract and Key Results

Innovations in beef production systems that enhance the nutritional and health value of beef lipids and their relationship with meat quality

Consumers are becoming more aware of the relationships between diet and health and this has increased consumer interest in the nutritional value of foods. This is impacting on the demand for foods which contain functional components that play important roles in health maintenance and disease prevention. For beef, much attention has been given to lipids. This paper reviews strategies for increasing the content of beneficial omega-3 polyunsaturated fatty acids (PUFA) and conjugated linoleic acid (CLA) and reducing saturated fatty acids (SFA) in beef. Particular attention is given to intramuscular fat (IMF) and the relationships between fatty acid composition and key meat quality parameters including colour shelf life and sensory attributes. Despite the high levels of ruminal biohydrogenation of dietary PUFA, nutrition is the major route for increasing the content of beneficial fatty acids in beef. Feeding grass or concentrates containing linseed (rich in α-linolenic acid, 18:3n-3) in the diet increases the content of 18:3n-3 and its longer chain derivative eicosapentaenoic acid (EPA, 20:5n-3) in beef muscle and adipose tissue, resulting in a lower n-6:n-3 ratio. Grass feeding also increases docasahexaenoic acid (DHA, 22:6n-3). Feeding PUFA rich lipids which are protected from ruminal biohydrogenation result in further enhancement of the PUFA in meat with concomitant beneficial improvements in the ratio of polyunsaturated:saturated fatty acids (P:S ratio) and n-6:n-3 ratio. The main CLA isomer in beef is CLA cis-9, trans-11 and it is mainly associated with the triacylglycerol lipid fraction and therefore is positively correlated with level of fatness. The level of CLA cis-9, trans-11 in beef is related to (1) the amount of this isomer produced in the rumen and (2) synthesis in the tissue, by delta-9 desaturase, from ruminally produced trans vaccenic acid (18:1 trans-11; TVA). Feeding PUFA-rich diets increases the content of CLA cis-9, trans-11 in beef. Trans-fatty acids in foods are of rising importance and knowledge of the differential effects of the individual trans isomers is increasing. TVA is the major trans 18:1 isomer in beef and as the precursor for tissue CLA in both animals and man should be considered as a neutral or beneficial trans-isomer. Increasing the content of n-3 PUFA in beef can influence colour shelf life and sensory attributes of the meat. As the content of n-3 PUFA increases then sensory attributes such as "greasy" and "fishy" score higher and colour shelf life may be reduced. Under these situations, high levels of vitamin E are necessary to help stabilise the effects of incorporating high levels of long chain PUFA into meat. However, grass feeding not only increases n-3 PUFA and CLA but, due to its high content of vitamin E, colour shelf life is improved. It is evident that opportunities exist to enhance the content of health promoting fatty acids in beef and beef products offering opportunities to add value and contribute to market differentiation. However, it is imperative that these approaches to deliver "functional" attributes do not compromise on the health value (lipoperoxidation) or the taste of beef products.