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41.
Jeremy Isaac Fisher John F. Mustard Matthew A. Vadeboncoeur 《Remote sensing of environment》2006,100(2):265-279
Despite the large number of in situ, plot-level phenological measurements and satellite-derived phenological studies, there has been little success to date in merging these records temporally or spatially. In this research, we bridge this scale gap through higher resolution satellite records (Landsat) and quantify the accuracy of satellite-derived metrics with direct field measurements. We compiled fifty-seven Landsat scenes from southern New England (P12 R51) from 1984 to 2002. Green vegetation areal abundance for each scene was derived from spectral mixture analysis and a single set of endmembers. The leaf area signal was fit with a logistic-growth simulating sigmoid curve to derive phenological markers (half-maximum leaf-onset and offset). Spring leaf-onset dates in homogenous stands of deciduous forests displayed significant and persistent local variability. The local variability was validated with multiple springtime ground observations (r2 = 0.91). The highest degree of verified small-scale variation occurred where contiguous forests displayed leaf-onset gradients of 10-14 days over short distances (< 500 m). These dramatic gradients occur in of low-relief (< 40 m) upland regions. The patterns suggest that microclimates resulting from springtime cold-air drainage may be influential in governing the start of leaf growth; every 4.16 m loss in elevation delayed spring leaf onset by 1 day. These microclimates may be of crucial importance in interpreting in situ records and interpolating phenology from satellite data. Regional patterns from the Landsat analyses suggest topographic, coastal, and land-use controls on phenology. Our results indicate that deciduous forests in the Providence, RI metropolitan area leaf out 5-7 days earlier than comparable rural areas. The platform-independent curve-fit methodology may be extended across platforms and field data. The methodologically consistent approach, in tandem with Landsat data, allows an effective scaling from plot to satellite phenological observations. 相似文献
42.
Ju Eun Lee David Walton Colleen P. OConnor Michael Wammes Jeremy P. Burton Elizabeth A. Osuch 《International journal of molecular sciences》2022,23(12)
Emerging adulthood (ages 18–25) is a critical period for neurobiological development and the maturation of the hypothalamic–pituitary–adrenal axis. Recent findings also suggest that a natural perturbation of the gut microbiota (GM), combined with other factors, may create a unique vulnerability during this period of life. The GM of emerging adults is thought to be simpler, less diverse, and more unstable than either younger or older people. We postulate that this plasticity in the GM suggests a role in the rising mental health issues seen in westernized societies today via the gut–brain–microbiota axis. Studies have paid particular attention to the diversity of the microbiota, the specific function and abundance of bacteria, and the production of metabolites. In this narrative review, we focus specifically on diet, physical activity/exercise, substance use, and sleep in the context of the emerging adult. We propose that this is a crucial period for establishing a stable and more resilient microbiome for optimal health into adulthood. Recommendations will be made about future research into possible behavioral adjustments that may be beneficial to endorse during this critical period to reduce the probability of a “dysbiotic” GM and the emergence and severity of mental health concerns. 相似文献
43.
Jeremy Rott Eva Teresa Toepfer Maria Bartosova Ana Kolevica Alexander Heuser Michael Rabe Geert Behets Patrick C. DHaese Viktoria Eichwald Manfred Jugold Ivan Damgov Sotirios G. Zarogiannis Rukshana Shroff Anton Eisenhauer Claus Peter Schmitt 《International journal of molecular sciences》2022,23(14)
Serum calcium isotopes (δ44/42Ca) have been suggested as a non-invasive and sensitive Ca balance marker. Quantitative δ44/42Ca changes associated with Ca flux across body compartment barriers relative to the dietary Ca and the correlation of δ44/42CaSerum with bone histology are unknown. We analyzed Ca and δ44/42Ca by mass-spectrometry in rats after two weeks of standard-Ca-diet (0.5%) and after four subsequent weeks of standard- and of low-Ca-diet (0.25%). In animals on a low-Ca-diet net Ca gain was 61 ± 3% and femur Ca content 68 ± 41% of standard-Ca-diet, bone mineralized area per section area was 68 ± 15% compared to standard-Ca-diet. δ44/42Ca was similar in the diets, and decreased in feces and urine and increased in serum in animals on low-Ca-diet. δ44/42CaBone was higher in animals on low-Ca-diet, lower in the diaphysis than the metaphysis and epiphysis, and unaffected by gender. Independent of diet, δ44/42CaBone was similar in the femora and ribs. At the time of sacrifice, δ44/42CaSerum inversely correlated with intestinal Ca uptake and histological bone mineralization markers, but not with Ca content and bone mineral density by µCT. In conclusion, δ44/42CaBone was bone site specific, but mechanical stress and gender independent. Low-Ca-diet induced marked changes in feces, serum and urine δ44/42Ca in growing rats. δ44/42CaSerum inversely correlated with markers of bone mineralization. 相似文献
44.
45.
Jeremy N. Bailenson Nick Yee Ph.D. Scott Brave Ph.D. Dan Merget David Koslow 《Human-Computer Interaction》2013,28(3):325-353
ABSTRACT This article examines the phenomenon of Virtual Interpersonal Touch (VIT), people touching one another via force-feedback haptic devices. As collaborative virtual environments become utilized more effectively, it is only natural that interactants will have the ability to touch one another. In the work presented here, we used relatively basic devices to begin to explore the expression of emotion through VIT. In Experiment 1, participants utilized a 2 DOF force-feedback joystick to express seven emotions. We examined various dimensions of the forces generated and subjective ratings of the difficulty of expressing those emotions. In Experiment 2, a separate group of participants attempted to recognize the recordings of emotions generated in Experiment 1. In Experiment 3, pairs of participants attempted to communicate the seven emotions using physical handshakes. Results indicated that humans were above chance when recognizing emotions via VIT but not as accurate as people expressing emotions through nonmediated handshakes. We discuss a theoretical framework for understanding emotions expressed through touch as well as the implications of the current findings for the utilization of VIT in human-computer interaction. 相似文献
46.
White JB Beckford J Yadegarynia S Ngo N Lialiutska T d'Alarcao M 《Food chemistry》2012,131(4):1453-1459
A common feature of both apoptosis and inflammation is the activation of caspases. Caspases are aspartate-directed cysteine proteases that have numerous cellular targets. It has been discovered that several flavonoids are inhibitors of caspases. Flavonoids are members of a family of polyphenolic compounds from plants that have many biological properties, one of which is the ability to induce cell death. Some flavonoids are selective inhibitors of particular caspases. Since some of the inhibitory flavonoids are nevertheless cytotoxic, these results suggest that flavonoid-induced cell death may be occurring through a non-classical apoptosis pathway that is not dependent on caspase activity. 相似文献
47.
We develop a stable and high-order accurate finite difference method for problems in earthquake rupture dynamics in complex geometries with multiple faults. The bulk material is an isotropic elastic solid cut by pre-existing fault interfaces that accommodate relative motion of the material on the two sides. The fields across the interfaces are related through friction laws which depend on the sliding velocity, tractions acting on the interface, and state variables which evolve according to ordinary differential equations involving local fields. The method is based on summation-by-parts finite difference operators with irregular geometries handled through coordinate transforms and multi-block meshes. Boundary conditions as well as block interface conditions (whether frictional or otherwise) are enforced weakly through the simultaneous approximation term method, resulting in a provably stable discretization. The theoretical accuracy and stability results are confirmed with the method of manufactured solutions. The practical benefits of the new methodology are illustrated in a simulation of a subduction zone megathrust earthquake, a challenging application problem involving complex free-surface topography, nonplanar faults, and varying material properties. 相似文献
48.
One possibility presented by novel communication technologies is the ability for remotely located experts to provide guidance to others who are performing difficult technical tasks in the real world, such as medical procedures or engine repair. In these scenarios, video views and other visual information seem likely to be useful in the ongoing negotiation of shared understanding, or common ground, but actual results with experimental systems have been mixed. One difficulty in designing these systems is achieving a balance between close-up shots that allow for discussion of detail and wide shots that allow for orientation or establishing a mutual point of focus in a larger space. Achieving this balance can be difficult without disorienting or overloading task participants. In this article we present results from two experiments involving three automated camera control systems for remote repair tasks. Results show that a system providing both detailed and overview information was superior to systems providing only one or the other in terms of performance but that some participants preferred the detail-only system. 相似文献
49.
Sergio Gómez-Alonso Vanessa J. Collins David Vauzour Ana Rodríguez-Mateos Giulia Corona Jeremy P.E. Spencer 《Food chemistry》2012,130(3):493-500
The moderate consumption of red wine has been proposed to reduce the incidence of colorectal cancer. Its anti-cancer action my in part be mediated by the actions of polyphenols on colon cancer epithelial cells. We show that a red wine phenolic (50 μg/ml) extract devoid of anthocyanins (removed to reflect polyphenol bioavailability to the large intestine) and the major red wine flavonols quercetin, myricetin, laricitrin and syringetin (50 μM) are capable of inhibiting the proliferation of colorectal epithelial adenocarcinoma cells. This anti-proliferative activity was partly mediated by the direct cytotoxic actions of flavonols and also their ability to cause a significant cell cycle blockage in G2/M. The anti-proliferative effects induced by flavonols were preceded, in most cases, by a strong and significant reduction of cyclooxygenase-2 (COX-2) and cyclin D1 expression. These results indicate that the observed inverse correlation between colon cancer and a moderate red wine intake may be partly mediated by the actions of red wine flavonols on the growth of cancer cells. 相似文献
50.
Jeremy Agte Olivier de Weck Jaroslaw Sobieszczanski-Sobieski Paul Arendsen Alan Morris Martin Spieck 《Structural and Multidisciplinary Optimization》2010,40(1-6):17-33
This paper is a summary of topics presented and discussed at the 2006 European–U.S. Multidisciplinary Optimization (MDO) Colloquium in Goettingen, Germany, attended by nearly seventy professionals from academia, industry, and government. An attempt is made to accurately reflect the issues discussed by this diverse group, qualified by interest, experience, and accomplishment to present an opinion about the state-of-the-art, trends, and developments in Multidisciplinary Design Optimization. As such, its main purpose is to provide suggestions and stimulus for future research in the field. The predominant content of the colloquium was centered on aerospace, with a few contributions from the automotive industry, and this is reflected in the article. Due to the timeframe that has passed since the conclusion of the workshop, the authors have updated topics where appropriate to reflect observed developments over the past 3 years. Finally, rather than dwelling extensively on past accomplishments and current capabilities in MDO we focus on the needs and identified shortcomings from the colloquium which lead to potential future research directions. A brief MDO background is provided to set the discussion in its proper context. 相似文献