BioFET sensor for detection of albumin in urine

Characterisation of a BioFET for detection of albumin in a mixture of human urine is presented. To avoid electrolyte effect of the urine, it was measured in PBS (phosphate buffer saline) at a fixed pH after albumin binding. The drain current was modulated by the albumin bound to the anti-albumin immobilised on the gate surface of the BioFET. The current variation ratio was likely to be proportional to the concentration of the albumin in the range 50-250 mg/1. The results show the feasibility of the BioFET as a urinary albumin sensor.     

Necessary optimality conditions in a nonsmooth control problem with variable structure

An optimal control problem with nonsmooth performance criterion described by a system of ordinary differential equations is considered. Necessary first-order optimality conditions are obtained.     

Electro-osmotic transport in charged cylindrical micro- and nano-channels

Present paper deals with the electro-osmotic flow in a infinitely extended cylindrical micro- and nano-channel. The channel height is considered to be much less than the channel length. We consider a mixture of water or another neutral solvent and a salt compound such as sodium chloride for which the ionic species are entirely dissociated. We have developed a two-dimensional numerical model to analyze the flow characteristics and concentration distributions of a electro-osmotic flow without using the Debye-Hückel approximation. The governing system of equations consist of the mole fractions of ions, the potential and the fluid flow equations. Results are produced for the case, where the channel height is much greater than the width of the electric double layer (EDL) (micro-channel) and for the case where the channel height is of the order of the width of the EDL (nano-channel). For various values of mole fraction, we studied the electro-osmotic flow profiles and the potential distribution along the channel at different channel heights. In this case of steady flow the velocity field and the potential are identical. The electro-osmotic flow produces a uniform ‘plug profile’ at channel heights greater than 20 nm, which results in reduced sample species dispersion as compared to the velocity gradients associated with the pressure driven flows. Asymptotic solutions are obtained when the flow in a micro-channel is considered.     

Biaxiale Ermüdung reibrührgeschweißter Strukturelemente

Biaxial fatigue of friction stir welded stiffened panels Within the framework of the European WelAir project, cruciform specimens made from stiffening FSW overlap joints were fatigued in the DLR biaxial test rig. To resemble the loading situation of pressurized fuselage structures, proportional loading without any phase shift, but with different load ratios λ between the loading components in both directions was applied.Natural crack initiation and subsequent crack growth were governed by the stiffness gradient caused by introducing the stringer. Cracks initiated and propagated at run‐in and run‐out locations in a direction perpendicular to the weld seam. The shortest fatigue life was observed for uniaxial loading in welding direction (λ = 0). An additional stress component perpendicular to the joint line (λ > 0) resulted in a higher number of cycles to failure. Similar to single stringer panels, increasing the load ratio also increased the number of cycles to failure for FSW clip‐stringer structural members, but additionally gives a different location of the fatal crack.     

Problem on estimation of the content of <Superscript>131</Superscript>I in milk in the “iodine” period of the Chernobyl accident

Measurements of the beta-activity of milk, serving as the main source of information on the radioactive contamination of the environment by the iodine isotope ¹³¹I, carried out on a DP-100 radiometer in the early post-Chernobyl period (1986) in Belarus, have been mathematically simulated. The results obtained allow the conclusion that the indicated measurements should be analyzed again with consideration for all of the nuclides present in milk. __________ Translated from Inzhenerno-Fizicheskii Zhurnal, Vol. 80, No. 6, pp. 102–108, November–December, 2007.     

Personality and the predisposition to engage in risky or problem behaviors during adolescence.

Longitudinal data from a representative sample of 1,978 Black and White adolescents were used to examine the role of personality in multiple risk or problem behaviors. Results indicate that covariation among diverse behaviors (educational underachievement, delinquent behavior, substance use, sexual behavior) can be adequately modeled by a single higher order factor, and that impulsivity and avoidance coping serve as generalized risk factors for involvement in these behaviors. Whereas none of the personality variables examined explained change in problem behaviors once established, avoidance coping prospectively predicted involvement among a subgroup of adolescents with little or no prior involvement. Results suggest that dysfunctional styles of regulating emotions and emotionally driven behaviors are core features of risky or problem behaviors during adolescence. (PsycINFO Database Record (c) 2010 APA, all rights reserved)