Comparison of measured value and calculated value of multiplestability in forced-flow cooled superconductors

The multiple stability observed exclusively in forced-flow cooled superconductors is numerically calculated, and the result is quantitatively compared with the value measured by J.W. Lue et al. (1980). The calculated and measured values agreed well in certain cases, and did not in others. Based on this comparison, the effects of the transient heat transfer coefficient and ohmic heat generation on the quantitative prediction of stability are discussed. From this comparison, it is learned that a precise understanding of the transient heat transfer coefficient is essential for reliable predictions, and also that the ordinary evaluation method of ohmic heat generation, which considers the flux-flow resistance, tends to overevaluate the situation     

"Pored-domes" of the fenestrated endotheliocyte of the glomerular and peritubular capillaries in the rodent kidney.

The fenestrated endotheliocyte of peritubular and glomerular capillaries in rat and mouse kidneys were observed with SEM and TEM. In the glomerular capillary, so-called "pored-domes" were found not only at the fenestrated areolae but also at the nuclear region of the endotheliocyte. At the region between filtration surface and nuclear region, they accumulated to construct a sponge-like structure. The endotheliocyte of peritubular capillary also showed small "pored-domes". The size and morphology of the pores in the "pored-domes" of glomerular and peritubular capillaries were similar to those of areolae fenestratae of the respective capillary. Based on the findings, we assumed that pored-domes and the sponge-like structure are the reservoir for the fenestrated area of the endotheliocyte to accommodate the rapid expansion of capillary lumen.     

Highly efficient configuration of a Pr3+-doped fluoridefiber amplifier module with an optical circulator

A highly efficient Pr³⁺-doped fluoride fiber amplifier configuration with an optical circulator, in which the input signal light is amplified both forward and backward through a Pr³⁺-doped fluoride fiber, is investigated with a view to decreasing the drive current and improving the reliability of pump laser diodes (LD's). With this double-path configuration, a 25-dB signal gain is achieved at an LD drive current of 110 mA. This LD drive current is about half that needed for a conventional single-path configuration. It is also found that this double-path configuration provides a double-gain coefficient, a slightly low saturation power, and a slightly narrow spectral gain width     

Experimental demonstration of soliton data transmission over unlimited distances with soliton control in time and frequency domains

A 2/sup 9/-1 pseudorandom-binary-sequence soliton signal has been transmitted experimentally over one million km for the first time with no degradation in the bit error rates. The synchronous modulator was driven by a timing clock signal extracted from the transmitting data signal. These results mean that it is possible to send soliton data signals over unlimited distances through the use of soliton control in the time and frequency domains.<>     

Characteristics of Gbit/s optical receiver sensitivity and long-span single-mode fiber transmission at 1.3 µm

Sensitivity of a 1.3 μm Ge APD receiver was measured at data rates ranging from 100 Mbits/s to 2 Gbits/s, using a high-speed GaAs FET RZ driver, low-noise Si bipolar transistor (BIT) receiver amplifier, and a highly sensitive TD comparator. The required received optical level at a 10^-9error rate was -31.9 dBm for 2 Gbits/s with a Ge APD/Si BIT front end having a 50 Ω input impedance. A Ge APD/ GaAs FET front end, with a 500 Ω input impedance, brought about 2 dB improvement at 100 Mbits/s, as compared with a Ge APD/Si BIT (50 Ω) front end. A coupling loss of 4 dB, achieved by a hemispherical microlens tipped on a single-mode fiber, and a low fiber loss of 0.57 dB/km, including splice loss, enabled 44.3 km single-mode fiber transmission at 2 Gbits/s. The 1.3 μm transmission system has a data rate repeater-spacing product of 88.6 (Gbit/s)km. Prospects of Gbit/s receiver sensitivity and the 2 Gbit/s transmission system, with more than 50 km repeater spacing, are also discussed.     

Mutational analysis of structure--activity relationships in human tumor necrosis factor-alpha

To determine the region of human tumor necrosis factor-alpha(TNF-), essential for cytotoxic activity against mouse L-M cells,single amino-acid-substituted TNF- mutant proteins (muteins)were produced in Escherichia coli by protein engineering techniques.An expression plasmid for TNF- was mutagenized by passage throughan E.coli mutD5 mutator strain and by oligonucleotide-directedmutagenesis. Approximately 100 single amino-acid-substitutedTNF- muteins were produced and assayed for cytotoxic activity.The cytotoxic activities of purified TNF- muteins, e.g. TNF-31T,-32Y, -82D, -85H, -115L, -141Y, -144K and -146E, were < 1%of that of parent TNF-. These results indicate that the integrityof at least four distinct regions of the TNF- molecule is requiredfor full biological activity. These regions are designated asfollows: region I, from position 30 to 32; region II, from position82 to 89; region III, from position 115 to 117; region FV, fromposition 141 to 146. In addition, TNF-141Y could not completelycompete with parent TNF- for binding to the receptor. This demonstratesthat region IV, and at least aspartk acid at position 141, mustbe involved in the TNF receptor binding site.     

Shallow donor impurities in InP bulk crystals grown by the synthesis, solute-diffusion technique

Far-infra-red photoconductivity measurements are used to study residual shallow donor species in InP bulk crystals grown by the synthesis, solute-diffusion technique. The observation of 1s-2p, m =+ 1 Zeeman transitions between the shallow donor-impurity states reveals that two dominant residual donors are included in the InP bulk crystals having carrier concentrations of less than 1 × 1015 cm?3 The donors are tentatively identified as Si and S.     

s-Shaped Software Reliability Growth Models and Their Applications

The s-shaped growth curves of detected software errors can be observed in software testing. The delayed s-shaped and inflection s-shaped software reliability growth models based on a nonhomogeneous Poisson process are discussed. The software reliability growth types of the models are investigated in terms of the error detection rate per error. In addition, a viable method for the software quality assessment, which integrates the capture-recapture method and the models above, is discussed, and its application to actual test data is illustrated.     

Abrupt changes in cross polarizations observed during thunder

Abrupt changes in the cross-polarization discrimination (XPD) and cross-polar phase were observed in cross-polarization measurements at 4, 6, and 11 GHz on propagation paths with low elevation angles. These abrupt changes were always observed during thunder, though exact time-to-time correspondence with lightning strokes was not clear in the measurement. In most cases, these sudden changes occurred in the direction in which the distortion of polarization ellipse increases, and the rate of change in XPD was much faster than rain-induced depolarizations by an order of magnitude. Based on the simultaneous measurement of circular and linear polarizations at 11 GHz, it was also found that the differential phase shift component suddenly increased to as large as20degto40degupon occurrence of these XPD changes, which confirms that this phenomenon is attributed to the effect of ice particles.