The talking cure: About language.

This article reviews the panel held at the 20th Annual Spring Meeting, Division of Psychoanalysis (39), American Psychological Association, April 6, 2000, San Francisco. The panelists were Judith Butler and Adrienne Harris, and the moderator was Jeanne Wolf Bernstein. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Suppression of tumorigenicity of rat liver epithelial tumor cell lines by a putative human 11p11.2-p12 liver tumor suppressor locus

We have previously identified and mapped a locus within human chromosome 11p11.2-p12 that suppresses the tumorigenic potential of a rat liver tumor cell line (termed GN6TF) which contains well defined chromosomal aberrations involving rat chromosomes 1, 4, 7, and 10. In the present study, we investigated the potential of this human 11p11.2-p12 liver tumor suppressor locus to suppress the tumorigenic potential of two other rat liver tumor cell lines (GN3TG and GP10TA) following microcell-mediated introduction of human chromosome 11. These tumor cell lines are aneuploid and contain chromosomal abnormalities that are similar to the GN6TF tumor line. The tumorigenic potential and other phenotypic characteristics of GN3TG-11neo and GP10TA-11neo microcell hybrid (MCH) cell lines were variable, and dependent upon the status of the introduced human chromosome 11. MCH cell lines that retained the region of 11p11. 2-p12 delineated by microsatellite markers D11S1385 and D11S903 exhibited suppression of tumorigenicity in vivo (decrease in tumorigenicity and/or elongation of latency), whereas, the tumorigenic potential of one MCH line that lacked markers in this region of human 11p11.2-p12, but retained flanking markers, was not changed from that of the parental tumor cell line. The chromosomal interval between microsatellite markers D11S1385 and D11S903 encompasses the previously localized minimal liver tumor suppressor region, suggesting that a common locus is responsible for tumor suppression among the rat liver tumor cell lines examined. The results of the present study have verified the presence of a liver tumor suppressor locus within human 11p11.2-p12, and have identified a substantial number of microsatellite markers that are closely linked to this tumor suppressor region. These chromosomal markers will facilitate positional cloning of candidate genes from this region, and may prove useful for determining the involvement of this locus in the pathogenesis of human liver cancer.     

Pole/zero cancellations in the general ∞ problem with reference to a two block design

Necessary and sufficient conditions are given for pole/zero cancellations in the close--loop transfer function from input disturbances to error signals in the general _∞ problem. These pole/zero cancellations can place restrictions on the suitability of particular _∞ design procedures. This will be shown by reference to a typical two-block design procedure.     

COMPOSITIONAL OPTIMIZATION FOR A SUPERIOR ASPHALT BINDER

The aging characteristics of naphthene aromatic (NA) and polar aromatic (PA)fractions of an aromatics material were investigated by studying the viscosity and other related properties of aged NA, PA and combined NA and PA fractions of five SHRP core asphalts (AAA-1, AAD-1, AAF-1     

Rational approximation of a class of infinite-dimensional systems I: Singular values of hankel operators

In order to establish the optimal rates of convergence for the infinity-norm rational approximation problem, upper and lower bounds on the singular values of a class of Hankel operators are established. These asymptotically accurate estimates are derived from results on the singular values of Hankel operators with symbol equal to the product of a rational function and an exponential function, combined with results on Hankel integral operators (in continuous time) whose kernels have certain smoothness properties.