Probability of malignant degeneration of ovarian tumors. Clinical study on the probability of malignant degeneration

More than 600 cases of ovarian tumors were analyzed for histological type, age of patient, bilateral occurrence, mobility and malignant degeneration in restant ovaries. Tumors of germinal epithelial origin show the highest incidence (24%) of malignant degeneration, tumors of germ cells the lowest (3,5%). Incidence of malignant degeneration increases in relation to the age of the patient from 2% (and under 30 years) to 36,5% (60-70 years). Each form of tumor has its typical age peak, which is about 20 years higher for carcinomas than for their benign counterpart. Bilateral ovarian tumors are malignant in 29%, one-sided only in 13%. Among freely movable ovarian tumors, only 6% enclose a malignant tumor, among adhaerent ones 34%. The examination of the prognosis of granulosacell-tumors, dysgerminomas and teratoblastomas is based on a larger material.     

Transient and Energy Transfer Studies of Bianthrone and Related Compounds in Fluid and Rigid Media

The photochromic modification of bianthrone can be produced through a triplet excited state at room temperature in fluid media, as shown by biacetyl photosensitization and phosphorescence quenching. A triplet state of these compounds is observed at 77 K in a methanol ethanol glass, but it is not established if this is the photochromic precursor.     

Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases

A combined cholestatic-hepatocellular injury and noncaseating granulomas occurred in two patients 1 and 4 weeks after phenylbutazone therapy. Both patients were jaundiced, one had a macular rash, and both had peripheral blood eosinophilia. Symptoms and signs subsided, and abnormal findings from tests of hepatic function rapidly returned to normal following withdrawal of the drug. Sections of liver biopsy specimens 6 months later showed no granulomas or other pathologic changes. Previously reported cases are reviewed.     

Constant-Current Wafer-Level Electromigration Test: Normalization of Data for Production Monitoring

Reliability monitoring is an important part of process control in high-volume production. For metallization, a wafer-level electromigration (WL-EM) test is usually the method of choice to get a good indication of process variation. Different WL-EM methods have been reported, including a constant current method, the SWEAT test, the isothermal test, and the breakdown energy of metal test. The method used in this paper uses the ramping procedure for the isothermal test to achieve the target temperature, but then hold the current constant without feedback correction once the target temperature has been achieved. We present practical normalization procedures to ensure an appropriate wafer-to-wafer comparison that is independent of variation in cross-sectional area as well as of the initial resistance spread. The measurements were performed on a commercially available 200-mm multiside probe station using custom software to implement the current ramp and resistance measurement. Test conditions were achieved through Joule heating; the test structures used were 800-mum-long single lines (no vias) in metal 1 to metal 3, varying in width from 0.14 to 10 mum. Due to variations in the hardware and in the temperature coefficient of resistance (TCR), several normalization steps (described below) were necessary in demonstrating reasonable and expected trends in the data. Results of the analysis suggest that the appropriate value for the current density exponent for this test methodology is two, and they also verify that the TCR varies with linewidth, decreasing as linewidth decreases.     

基于热负荷变化的后混合饮料机温度控制参数优化整定

介绍后混合饮料机的工作原理,分析CCDX型后混合饮料机温控参数设置的固有缺陷,通过改变糖浆的冷却方式,并利用NTC测得的温度和时间的比值(即升/降温速度)来反映热负荷的变化,从而设定不同的压缩机开/关机温度值.测试结果表明,本文所提的温度参数优化整定方法能有效地解决不能同时满足为了得到合格的饮料所需要的狭窄的温控范围和...     

Is leptin sensitivity the link between smoking cessation and weight gain?

We performed a case-control study to investigate the association of the poor metaboliser genotype of the cytochrome P450 2D6 gene with Parkinson's disease (PD). Genotyping was determined by the polymerase chain reaction followed by digestion with restriction enzymes. The poor metaboliser genotype was more frequent in 112 patients with PD than in 206 matched controls (odds ratio 1.7, 95% CI: 0.94-2.45). A meta-analysis of these results together with ten other published studies gave a pooled odds ratio for the poor metaboliser genotype of 1.47 (95% CI: 1.18-1.96, P=0.01). Thus, the poor metaboliser genotype has a small but highly significant association with PD which would be easily missed in small studies. Research now should focus on the mechanism of this association.