The use of transgenic animals in biotechnology

Conformational effects and affinities of VP-16 (etoposide) and its derivatives to DNA in the presence of Cu(II) ion were examined by circular dichroic (CD) spectra. The Cu(II)/Cu(I) redox kinetics and the hydroxyl radical (.OH) generation from the Cu(II)-complexes were estimated by the stopped-flow kinetics. Based on the results, DNA-cleaving activity of Cu(II)-complexes of VP-16 has been shown to be related with binding affinity of the complex to DNA, Cu(II)/Cu(I) redox and .OH generation, emphasising the mechanism of generated .OH attack to DNA.     

Prevalence of voice problems in teachers

Teachers are frequently cited as experiencing a high rate of vocal dysfunction (1-7). Despite considerable research in the area of voice problems in teachers, the prevalence of voice disorders in this group is unknown. This study investigated the prevalence of self-reported voice problems in teachers using a mail survey of a simple random sample of 1168 state school teachers (preschool-Grade 12) in South Australia. As part of the survey, teachers were asked to report voice problems for the day of the survey, during the current teaching year, and during their careers. The response rate was 75%, with 16% of teachers reporting voice problems on the day of the survey, 20% reporting problems during the current teaching year, and 19% reporting problems at some time during their career. Females were twice as likely as males to report voice problems. These findings clearly indicate a need for further investigation of the causes of vocal dysfunction in teachers and for the development of educational programs aimed at preventing voice problems in this group of professional voice users.     

Assessing obesity: classification and epidemiology

Obesity is generally defined as a body mass index (BMI) of 30 kg/m2 and higher. Overweight is defined as a BMI between 25 and 30 kg/m2. The prevalence varies considerably between countries, and between regions within countries. It is estimated that more than half of adults aged 35-65 living in Europe are either overweight or obese. Overweight is more common among men than among women but obesity is more common among women. The prevalence of obesity in Europe is probably in the order of 10-20% in men and 15-25% in adult women. In most European countries who have reliable data on time-trends the prevalence of obesity seems to be increasing. In most European countries, obesity is usually inversely associated with socio-economic status, particularly among women. New classifications of overweight may be based on cut-off points for simple anthropometric measures which reflects both total adiposity as well as abdominal fatness.     

火焰动画快速模拟的新方法

针对火焰动画难以快速建模和绘制的问题,提出了完全利用GPU过程化生成火焰动画的高效算法。先用建模工具在预处理阶段构建一个由平面正方形组成的三维模型,在绘制阶段通过GPU编程对这些方形进行Billboard方式的变换,并用一些简单公式对他们的运动方式、大小和颜色来用过程化方式进行控制,最后通过alpha混合得到最终结果。算法完全在GPU里实现,能满足实时的绘制要求。     

A deep multi-source adaptation transfer network for cross-subject electroencephalogram emotion recognition

Neural Computing and Applications - In real-world application of affective brain–computer interface (aBCI), individual differences across subjects and non-stationary characteristics of...     

基于参数空间法的飞行器再入控制研究

针对空天飞行器再入段环境变化剧烈、气动参数变化范围大的特点,采用参数空间方法来设计其控制系统;首先建立飞行器控制系统的数学模型,鉴于飞行器再入过程中对攻角有着严格的要求,设计了以攻角反馈为被控信号的三回路自动驾驶仪结构,然后根据参数空间方法求出对应的控制器参数,最后基于Matlab/Simulink的非线性仿真表明,所设计的控制系统在大气密度偏差±30%、气动力/力矩系数各偏差±20%的组合偏差情况下仍具有较好的鲁棒稳定性和跟踪性能。     

Delay‐dependent stability for Markovian genetic regulatory networks with time‐varying delays

This paper is concerned with the problem of stochastic stability analysis for a class of genetic regulatory networks with Markovian jump parameters and time‐varying delays. A delay‐dependent stability criterion is derived by using a novel mode‐dependent Lyapunov functional. The derived stability criterion is expressed in terms of linear matrix inequalities and is less conservative than the existing ones in the literature. A numerical example is provided to demonstrate the effectiveness of the proposed stability criterion. Copyright © 2011 John Wiley and Sons Asia Pte Ltd and Chinese Automatic Control Society     

Growth characteristics of β-SiC by chemical vapour deposition

A twin-plane re-entrant corner effect (TPRE) in growth of chemical vapour deposited (CVD) -SiC is described by the film and particles of gas-phase homogeneous nucleation. The structural morphology has been characterized by scanning electron microscopy and transmission electron microscopy. Morphological characteristics of the deposited crystals, such as triangularity, hexagons or facets have been explained in terms of the re-entrant corner effect at twin junctions, which were proposed as preferential growth sites for perfect crystals. For real deposits, screw dislocations and/or the re-entrant corner effect are not expected to be compatible. The majority of chemical vapour deposited SiC crystals have a high defect density comprised of {111} twins and dislocations associated with the process variables. Infrared transmission spectra and electron spectroscopy of chemical analysis indicated that the major chemical bonds of CVD -SiC were Si-C and C-H bonds. The positions of the 1s or 2p corelevel peaks for deposits are described.     

Piezoelectric and acoustic properties of potassium titanyl phosphate (KTP) and its isomorphs

The bulk elastic and piezoelectric properties of potassium titanyl phosphate (KTP) and some of its family members such as RbTiOPO(4 ) (RTP) and RbTiOAsO(4) (RTA) have been determined. The piezoelectric, elastic, and dielectric matrix (P-E-D) of KTP has been completely characterized. Values for the temperature dependence of the expansion coefficients and elastic constants have been obtained, and the effects of variations in dielectric constant on coupling coefficient determined. The major diagonal elements of the piezoelectric and elastic matrices of RTP and RTA were measured as were the thermal expansion coefficient of all the KTP isomorphs, KTP in the temperature range 25-80 degrees C, is shown to have a combination of large coupling coefficients (up to k(t)=38% for hydrothermally grown KTP) and medium temperature dependence coefficients of elastic constant (as low as 40 p.p.m./ degrees C for tau(c33) for hydrothermally grown KTP) that makes it attractive for many piezoelectric applications.