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101.
KP Dingemans MA van den Bergh Weerman RF Keep PK Das 《Canadian Metallurgical Quarterly》1994,57(3):433-439
We have previously reported that an invasive morphotype can be evoked in a rat colon carcinoma by transplanting it into pre-induced subcutaneous granulation tissue. We have now studied the interaction of the same tumor with liver tissue, which is extremely poor in connective tissue in comparison with the subcutaneous site. Tumor cells were injected into the portal system and the resulting experimental liver metastases were examined by electron microscopy and immunohistochemistry. Early metastases consisted of well-differentiated acini, fully surrounded by connective tissue that was derived from the periportal stroma. In a later stage, this connective tissue was overgrown by tumor cells and, almost immediately, acinar differentiation was lost. Most metastases eventually reached the liver capsule, which reacted by forming a layer of granulation tissue. Only in this layer, we observed invasion by thin tumor cell strands, which were often intimately associated with fibroblasts or with blood capillaries. The tumor cells remained smooth and rounded during this process. After fully penetrating the granulation tissue, the tumor cell strands reached the liver surface, where they formed poorly structured papillary masses that were nearly devoid of stroma. Our observations indicate that, even in a relatively homogeneous organ like the liver, the tumor-host interaction is highly complex and dynamic. They also confirm the notion that granulation tissue stimulates tumor invasiveness. Finally, they show that tumor cells can actively invade host tissues without exhibiting a "fibroblastic" morphology. 相似文献
102.
For studying flow problems involved with complex physics it is now common to use numerical field methods for solving Navier-Stokes or Euler equations. However, for a large class of fluid mechanics problems, which can be dealt with linearized potential equations, the boundary element method proves to be quite useful, especially for its easy application and relatively less computational effort compared to the field methods. The boundary element method has undergone some significant advancements in the last decade with respect to the study of steady and unsteady flow problems concerning wing aerodynamics in compressible medium, flow fields of propellers and rotors and acoustical disturbance propagation from moving bodies. In this paper a few recent contributions which evolved in the DLR as research projects and as doctoral and diploma thesis of the Technical University Braunschweig are concisely described.List of symbols
a
Sound velocity
-
b
Span of a wing
-
c
p
Coefficient of static pressure
-
c
dp
Coefficient of profile drag
-
c
1, c
d, cm
Coefficient of lift, drag and moment per unit span width
-
c
L, cD, cM
Total lift, drag and moment-coefficients
-
c
T, cP
Thrust and power-coefficient of a propeller
-
d
Distance
- D
Doublet strength
-
e
Specific heat energy
-
E
Total energy in a moving medium element
-
f
Frequency
-
F
Field point
-
g
Gravitational acceleration
-
h
Radial distance in cylinder coordinates
-
I
1, I
2
Inducing functions
-
i, j, k
Unit vectors in cartesian coordinates
-
k
Wave number [/a
]
-
l
Local wing-chord
-
l
0, l
v
Length of singularity element at t
oand t
v
-
m
Notation for Fourier-component
-
M, M
*
Mach number based on local and critical sound speed
-
n
Number of rotation per second
- n
Unit normal vector to a surface 相似文献
103.
We reviewed 410 cases, 365 males and 45 females, mean age 64 years, of inguinal and femoral hernia, from 1/1/1991 to 31/12/1994, repaired with Lichtenstein and Trabucco techniques. Recurrent hernias repaired were 36 (8,8%). Local anesthesia was used in 82% and follow-up has ranged from 6 months to 4 years. The meshes used are made with a single layer of polipropylene and the Trabucco plugs T1 were made by hand at the operating table. In our experience these two techniques are simple, but is very important, before application of the mesh, a correct dissection of inguinal region. We made a complete excision of cremasteric fibers preservig, if possible, the genital branch of the genitofemoral nerve. The transversalis fascia is introflected and sutured in direct hernia repair or when there are a loss of tissues. The preliminary results obtained with the "tension free" hernioplasty are satisfying. The most important complications were 9 hematomas and an important and persistent inguinal neuralgia in 1 case. There were no recurrences, but we must considered the short follow-up period. 相似文献
104.
Data-driven next-generation smart grid towards sustainable energy evolution: techniques and technology review 下载免费PDF全文
Faiaz Ahsan Nazia Hasan Dan Subrata K. Sarker Li Li S. M. Muyeen Md. Firoj Ali Zinat Tasneem Md. Mehedi Hasan Sarafat Hussain Abhi Md. Robiul Islam Md. Hafz Ahame Md. Manirul Islam Sajal K. Das Md. Faisal R. Badal Prangon Das 《电力系统保护与控制》2023,8(3):696-737
Meteorological changes urge engineering communities to look for sustainable and clean energy technologies to keep the environment safe by reducing CO2 emissions. The structure of these technologies relies on the deep integration of advanced data-driven techniques which can ensure efcient energy generation, transmission, and distribution. After conducting thorough research for more than a decade, the concept of the smart grid (SG) has emerged, and its practice around the world paves the ways for efcient use of reliable energy technology. However, many developing features evoke keen interest and their improvements can be regarded as the next-generation smart grid (NGSG). Also, to deal with the non-linearity and uncertainty, the emergence of data-driven NGSG technology can
become a great initiative to reduce the diverse impact of non-linearity. This paper exhibits the conceptual framework of NGSG by enabling some intelligent technical features to ensure its reliable operation, including intelligent control, agent-based energy conversion, edge computing for energy management, internet of things (IoT) enabled inverter, agent-oriented demand side management, etc. Also, a study on the development of data-driven NGSG is discussed to facilitate the use of emerging data-driven techniques (DDTs) for the sustainable operation of the SG. The prospects of DDTs in the NGSG and their adaptation challenges in real-time are also explored in this paper from various points of view including engineering, technology, et al. Finally, the trends of DDTs towards securing sustainable and clean energy evolution from the NGSG technology in order to keep the environment safe is also studied, while some major future issues are highlighted. This paper can ofer extended support for engineers and researchers in the context of data-driven technology and the SG. 相似文献
105.
Sliding mode controller design via delay-dependent H∞ stabilization criterion for load frequency regulation 下载免费PDF全文
This work presents a control approach based on sliding-mode-control (SMC) to design robust H∞ state feedback
controllers for load frequency regulation of delayed interconnected power system (IPS) with parametric uncertainties.
Considering both state feedback control strategy and delayed feedback control strategy, two SMC laws are proposed.
The proposed control laws are designed to improve the stability and disturbance rejection performance of delayed
IPS, while stabilization criteria in the form of linear matrix inequality are derived by choosing a Lyapunov–Krasovskii
functional. An artifcial time-delay is incorporated in the control law design of the delayed feedback control structure to enhance the controller performance. A numerical example is considered to study the control performance
of the proposed controllers and simulation results are provided to observe the dynamic response of the IPS. 相似文献
106.
The present work has been carried out to develop a performance evaluation framework of distribution network design in public health with specific reference to essential medicines based on six different types of public health distribution networks (PHDNs) prevalent across six Indian states. We evaluated the performance of PHDNs on the criteria of cost and service and also on the sub-criteria of cost and service by following the analytic hierarchy process. We utilized the pairwise comparison method in determining the relative importance of criteria and sub-criteria by seeking responses from several experts and subsequently evaluated the PHDNs on all sub-criteria in a 7-point Likert scale by seeking views from the same experts. Finally, we developed the “cost–service matrix,” in which cost and service have been depicted in the horizontal and vertical axes, respectively. We demonstrated the performance of six PHDNs in this matrix in terms of cost and service by plotting scores obtained by them on cost and service, respectively. The findings of the study provide rich insights to the policy planners of public health. 相似文献
107.
Deepa Das Rajendra Kumar Khadanga Deepak Kumar Rout 《International Journal of Communication Systems》2023,36(2):e5376
This paper investigates the resource allocation in a massively deployed user cognitive radio enabled non-orthogonal multiple access (CR-NOMA) network considering the downlink scenario. The system performance deteriorates with the number of users who are experiencing similar channel characteristics from the base station (BS) in NOMA. To address this challenge, we propose a framework for maximizing the system throughput that is based on one-to-one matching game theory integrated with the machine learning technique. The proposed approach is decomposed to solve users clustering and power allocation subproblems. The selection of optimal cluster heads (CHs) and their associated cluster members is based on Gale-Shapley matching game theoretical model with the application of Hungarian method. The CHs can harvest energy from the BS and transfer their surplus power to the primary user (PU) through wireless power transfer. In return, they are allowed to access the licensed band for secondary transmission. The power allocation to the users intended for power conservation at CHs is formulated as a probabilistic constraint, which is then solved by employing the support vector machine (SVM) algorithm. The simulation results demonstrate the efficacy of our proposed schemes that enable the CHs to transfer the residual power while ensuring maximum system throughput. The effects of different parameters on the performance are also studied. 相似文献
108.
Gopal Chandra Das Seemanti Saha Abhijit Bhowmick Santi P. Maity 《International Journal of Communication Systems》2023,36(5):e5431
An energy harvesting (EH) and cooperative cognitive radio (CR) network (CRN) is studied in this paper where CR users transmit data through a primary user (PU) channel if the channel remains idle, else an optimal number CRs helps in transmission of PU. To achieve the optimum number of CRs (ONCR) involved in cooperation, a novel scheme based on a combination of channel censoring and total error is proposed. The performance of the proposed scheme is investigated under RF harvesting scenario. The EH is dependent on sensing decision and a CR source harvests energy from PU's RF signal. The harvested energy (HE) is split into two parts: One part is used by the CR network (CRN) for its own transmission, and the other part is used for supporting PU. The effect of the energy allocation factor on total throughput is also investigated. New expressions for optimal number of CRs and throughput are developed. The effect of network parameters such as sensing time, censoring threshold, and energy allocation parameter (EAP) on throughput is investigated. Impact of distance between nodes is also studied. 相似文献
109.
Sunny Chilankamol Das Satyajit Martin Kevin J. M. Coussy Philippe 《Journal of Signal Processing Systems》2022,94(9):895-912
Journal of Signal Processing Systems - Research interest and industry investment in edge computing solutions have increased dramatically in recent years. Consequent quest for balanced performance,... 相似文献
110.
Medical practitioners are unduly stressed, leading to ill health, loss of work efficiency, sometimes affecting decision-making capability. The present study was conducted with the aim to quantify the psychosocial factors that affect the medical practitioners working in Indian hospitals. This study constructed and validated Re-Modified Work-Style Short Form Questionnaire, an eight-item instrument based on work style of 108 medical practitioners comprising Indian physicians and surgeons. The re-modified tool had acceptable validity and internal consistency, which the modified one did not. Explorative factor analysis identified and labelled three factors: ‘Working through pain’, ‘Deadlines/pressure’ and ‘Self-imposed workload’. The findings of the study reveal that the mean total work style score exceeded the standardised limits ≥16, which suggests that the work style of medical practitioners working in Indian hospitals are at risk which may precipitate psychosocial stress. Factor weights was derived through Analytic Hierarchy Process to prioritise the relative importance of three potential work-style factors. The study may help to increase the preventive strategies to proactively reduce the effect of risk factors for the precipitation of stress, successfully leading to its attenuation. 相似文献