Helicobacter pylori does not migrate from the antrum to the corpus in response to omeprazole

BACKGROUND: Omeprazole is known to have an effect on Helicobacter pylori in vivo. One opinion is that H. pylori "migrates" from the antrum to the corpus in response to omeprazole therapy. METHODS: To determine whether H. pylori migrates in response to omeprazole, we assessed the presence of H. pylori in the antrum and corpus in duodenal ulcer patients receiving omeprazole for 4 wk. Culture and histological examination of antral biopsies (Genta stain) were performed before patients received omeprazole, at the end of therapy, and 4-6 wk later. The end points were presence or absence of H. pylori and the number of H. pylori colonies per biopsy. RESULTS: Seventy-two patients had H. pylori in both the antrum and corpus at entry and 4-6 wk after ending therapy. Three general patterns were prevalent at the end of omeprazole therapy: antrum- and corpus-positive (54%), antrum-negative and corpus-positive (24%), both antrum- and corpus-negative (21%), and one patient had antrum-positive with corpus-negative (1%). Evaluation of the number of colonies per biopsy in those who remained H. pylori-positive in both the antrum and corpus throughout showed that the number of H. pylori decreased in both the antrum and corpus during therapy (507 +/- 60 vs. 225 +/- 51, p < 0.01 and 415 +/- 58 vs. 290 +/- 46 0.1) for antrum and corpus, respectively, and tended to return to pre-therapy levels 4-6 wk later. The number of H. pylori in the corpus also decreased in the antrum-negative and corpus-positive group during therapy with omeprazole (433 +/- 87 vs. 185 +/- 61, p < 0.05). In most of the patients studied, the number of H. pylori in the corpus was less posttreatment than it was pretreatment. The decrease in H. pylori load was also reflected in the development of false-negative urea breath tests. CONCLUSIONS: Omeprazole is detrimental to H. pylori in both the antrum and the corpus; migration from the antrum to the corpus in response to omeprazole is a myth.     

Some sexological characteristics of stress incontinent women

The goal of stress incontinence surgery is to prevent opening of the urethra during increases in intra-abdominal pressure. Greater refinements in the understanding of the pathophysiology of incontinence and experience with newer treatments have extended surgical thinking beyond the familiar paradigm "to place the urethra in a high retropubic position." When incontinence is associated with vaginal hypermobility, vaginal support may be sufficient to restore continence if the suburethral vaginal wall is sufficiently strong, an evaluation which must often be made by physical examination alone. However, when the vaginal wall is weak, the urethra will require an alternative form of support, usually a sling. If the urethra is intrinsically deficient, vaginal support may not be sufficient to prevent opening during increased intra-abdominal pressure, and coaptation by sling obstruction or periurethral bulking injection may be required. Most laparoscopic approaches to stress incontinence use Burch's method, which offers excellent urethral stability provided the suburethral vaginal wall is strong. Newer insights into the relation between vaginal mobility and urethral closure are discussed, as well as anatomic aspects of the Burch suspension relevant to laparoscopic repair.     

Concept-based evidential reasoning for multimodal fusion in human–computer interaction

Considerable research has been done on using information from multiple modalities, like hands, facial gestures or speech, for better interaction between humans and computers, and many promising human–computer interfaces (HCI) have been developed in recent years. However, most of the current HCI systems have a few drawbacks: firstly, they are highly dependent on the performance of individual sensors. S econdly, the information fusion process from these sensors tends to ignore the semantic nature of the modalities, which may reinforce or clarify each other over time. Finally, they are not robust enough at representing the imprecise nature of human gestures, since individual gestures are highly ambiguous in themselves. In this paper, we propose an approach for the semantic fusion of different input modalities, based on transferable belief models. We show that this approach allows for a better representation of the ambiguity involved in recognizing gestures. Ambiguity is resolved by combining the beliefs of the individual sensors on the input information, to form new extended concepts, based on a pre-defined domain specific knowledge base, represented by conceptual graphs. We apply this technique to a multimodal system consisting of a hand gesture recognition sensor and a brain computing interface. It is shown that the technique can successfully combine individual gestures obtained from the two sensors, to form meaningful concepts and resolve ambiguity. The advantage of this approach is that it is robust even if one of the sensors is inefficient or has no input. Another important feature is its scalability, wherein more input modalities, like speech or facial gestures, can be easily integrated into the system at minimal cost, to form a comprehensive HCI interface.     

Hybrid signal processing and machine intelligence techniques for detection,quantification and classification of power quality disturbances

This paper presents an advanced signal processing technique known as S-transform (ST) to detect and quantify various power quality (PQ) disturbances. ST is also utilized to extract some useful features of the disturbance signal. The excellent time–frequency resolution characteristic of the ST makes it an attractive candidate for analysis of power system disturbance signals. The number of features required in the proposed approach is less than that of the wavelet transform (WT) for identification of PQ disturbances. The features extracted by using ST are used to train a support vector machine (SVM) classifier for automatic classification of the PQ disturbances. Since the proposed methodology can reduce the features of disturbance signal to a great extent without losing its original property, it efficiently utilizes the memory space and computation time of the processor. Eleven types of PQ disturbances are considered for the classification purpose. The simulation results show that the combination of ST and SVM can effectively detect and classify different PQ disturbances.     

Transient temperature responses of hydronic radiant floor heating system by different pipe embedding depth and water supply condition

"Ondol" is a Korean unique heating system. It is a specific radiant floor heating system using combustion heat of briquette or timber in Korea. Such traditional "Ondol" is changed to radiant heating system with pipe-coil embedded in the floor or slab. This study has contributed to the understandings of the transient behaviours of Ondol-heated floor panels and enclosure exposed to this type of heating system. The result is that the water supply temperature had a large effect on the rate of increase in floor surface and room air temperature. But, in spite of a higher water supply temperature, the heat flow rate was not increased considerably. The shallow pipe embedding depths, of course, result in a low heat flow rate.     

MHD combined free and forced convection flow through two parallel porous walls

Summary The flow of a viscous conducting fluid between two parallel plates of infinite length (one of which is at rest and the other moving parallel to itself with a linear axial temperature variation) under the influence of a uniform transverse magnetic field is considered. It is assumed that the fluid is injected into the channel through the lower wall and sucked from the channel through the upper wall with the same velocityv ₀. The velocity and temperature distributions, the coefficient of skin friction and the rate of heat transfer coefficient are evaluated. The effects of magnetic parameterM, the suction Reynolds numberR, the Grashoff numberG and Binkmann numberB on the above mentioned physical quantities are investigated.With 21 Figures     

Characterization of CuAlO2 films prepared by dc reactive magnetron sputtering

Thin films of copper aluminum oxide (CuAlO₂) were prepared on glass substrates by dc magnetron sputtering at a substrate temperature of 523 K under various oxygen partial pressures in the range 1 × 10⁻⁴–3 × 10⁻³ mbar. The dependence of cathode potential on the oxygen partial pressure was explained in terms of oxidation of the sputtering target. The influence of oxygen partial pressure on the structural, electrical and optical properties was systematically studied. p-Type CuAlO₂ films with polycrystalline nature, electrical resistivity of 3.1 Ω cm, Hall mobility of 13.1 cm² V⁻¹ s⁻¹ and optical band gap of 3.54 eV were obtained at an oxygen partial pressure of 6 × 10⁻⁴ mbar.     

PEO／V2O5纳米复合薄膜的变色特性研究

为改善V2O5薄膜的电致变色性能，采用溶胶-凝胶法将具有高离子电导率并具有水溶性的聚环氧乙烷（PEO）直接嵌入V2O5层间，制备了PEO／V2O5纳米复合薄膜。采用标准三电极法从0．5mol／L LiClO4的PC电解质溶液向PEO／V2O5纳米复合薄膜注入锂离子，测量了纳米复合薄膜在注入不同数量锂离子时的可见光透射光谱以及对应的颜色变化，并运用循环伏安法测试其电化学性能。实验结果表明，PEO／V2O5纳米复合薄膜的循环伏安图出现了2对氧化还原峰，并且具有稳定的循环可逆性。随着应用电压的不同，薄膜呈现黄色、绿色和蓝色的多色可逆变化。PEO／V2O5纳米复合薄膜的电化学稳定性和机械性能都优于V2O5干凝胶薄膜，可以作为电致变色材料得到应用。X射线光电子能谱（XPS）成分分析表明PEO／V2O5纳米复合薄膜的电致变色效应与V、O的化合价和化学环境密切相关。