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Es werden die experimentellen und numerischen Ergebnisse dargelegt, um die gesamte Spannungs-Dehnungs-Kurve des Zugversuches mit sechs Kennwerten zu beschreiben. Dies sind: Elastizitätsmodul, Streckgrenze, Fließdehnung, Zugfestigkeit, Gleichmaßdehnung und Verfestigungsmodul. Dadurch werden auch im überelastischen Bereich numerische Beziehungen möglich zwischen: Verformungen und Spannungen, Dehngrenzen, Tangenten-Modulen und Arbeitsvermögen. Die Beziehungen erweitern die Ermittlung von Last- und Eigenspannungen, und die Berechnungen beim plastischen Umformen, beim Traglastverfahren und beim Messen von Kerbspannungen. 相似文献
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Watson M.E. Chilla J.L.A. Rocca J.J. Kim J.-W. Lile D.L. Vogt T.J. Robinson G.Y. 《Quantum Electronics, IEEE Journal of》1995,31(2):254-260
We report modulation saturation and time response measurements on InGaAs-InGaP MQW modulators. The measurements yield a saturation intensity of (3.7±0.1) kW/cm2 for a 0-10 V swing and switching times between 10 and 90 ns, depending on the bias voltage and incident light intensity. The observed dependence indicates that field screening due to carrier build-up is the dominant physical mechanism determining both the speed and the saturation intensity. This conclusion is supported by results of theoretical calculations 相似文献
45.
Klaus D. Mielenz Jack J. Hsia 《Journal of research of the National Institute of Standards and Technology》1990,95(5):545-548
The differences between ITS-90 and IPTS-68 above 1235 K are described. It is shown that none of the following CIE definitions or recommendations require revision because of the introduction of the ITS-90: International Lighting Vocabulary definitions; CIE Standard Illuminants A, D65, other illuminants; and sources for realizing CIE Illuminants. The effect of the ITS-90 on previously calibrated sources for realizing CIE illuminants is negligibly small.2 相似文献
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Zaffar Mubariz Garg Sourav Milford Michael Kooij Julian Flynn David McDonald-Maier Klaus Ehsan Shoaib 《International Journal of Computer Vision》2021,129(7):2136-2174
International Journal of Computer Vision - Visual place recognition (VPR) is the process of recognising a previously visited place using visual information, often under varying appearance... 相似文献
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Alexandre N. Tuch Eva E. Presslaber Markus Stöcklin Klaus Opwis Javier A. Bargas-Avila 《International journal of human-computer studies》2012,70(11):794-811
This paper experimentally investigates the role of visual complexity (VC) and prototypicality (PT) as design factors of websites, shaping users' first impressions by means of two studies. In the first study, 119 screenshots of real websites varying in VC (low vs. medium vs. high) and PT (low vs. high) were rated on perceived aesthetics. Screenshot presentation time was varied as a between-subject factor (50 ms vs. 500 ms vs. 1000 ms). Results reveal that VC and PT affect participants' aesthetics ratings within the first 50 ms of exposure. In the second study presentation times were shortened to 17, 33 and 50 ms. Results suggest that VC and PT affect aesthetic perception even within 17 ms, though the effect of PT is less pronounced than the one of VC. With increasing presentation time the effect of PT becomes as influential as the VC effect. This supports the reasoning of the information-processing stage model of aesthetic processing (Leder et al., 2004), where VC is processed at an earlier stage than PT. Overall, websites with low VC and high PT were perceived as highly appealing. 相似文献
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Thomas M. Ackermann Dr. Lars Allmendinger Dr. Georg Höfner Prof. Dr. Klaus T. Wanner 《ChemMedChem》2021,16(1):199-215
This study describes the first binding assay for glycine transporter 2 (GlyT2) following the concept of MS Binding Assays. The selective GlyT2 inhibitor Org25543 was employed as a reporter ligand and it was quantified with a highly sensitive and rapid LC-ESI-MS/MS method. Binding of Org25543 at GlyT2 was characterized in kinetic and saturation experiments with an off-rate of 7.07×10−3 s−1, an on-rate of 1.01×106 M−1 s−1, and an equilibrium dissociation constant of 7.45 nM. Furthermore, the inhibitory constants of 19 GlyT ligands were determined in competition experiments. The validity of the GlyT2 affinities determined with the binding assay was examined by a comparison with published inhibitory potencies from various functional assays. With the capability for affinity determination towards GlyT2 the developed MS Binding Assays provide the first tool for affinity profiling of potential ligands and it represents a valuable new alternative to functional assays addressing GlyT2. 相似文献
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Anne-Cathrine S. Vogt Tasneem Arsiwala Mona Mohsen Monique Vogel Vania Manolova Martin F. Bachmann 《International journal of molecular sciences》2021,22(9)
Iron is a critical metal for several vital biological processes. Most of the body’s iron is bound to hemoglobin in erythrocytes. Iron from senescent red blood cells is recycled by macrophages in the spleen, liver and bone marrow. Dietary iron is taken up by the divalent metal transporter 1 (DMT1) in enterocytes and transported to portal blood via ferroportin (FPN), where it is bound to transferrin and taken up by hepatocytes, macrophages and bone marrow cells via transferrin receptor 1 (TfR1). While most of the physiologically active iron is bound hemoglobin, the major storage of most iron occurs in the liver in a ferritin-bound fashion. In response to an increased iron load, hepatocytes secrete the peptide hormone hepcidin, which binds to and induces internalization and degradation of the iron transporter FPN, thus controlling the amount of iron released from the cells into the blood. This review summarizes the key mechanisms and players involved in cellular and systemic iron regulation. 相似文献
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