全文获取类型
收费全文 | 1259篇 |
免费 | 0篇 |
专业分类
综合类 | 4篇 |
化学工业 | 5篇 |
金属工艺 | 1篇 |
机械仪表 | 7篇 |
建筑科学 | 2篇 |
能源动力 | 1篇 |
轻工业 | 6篇 |
水利工程 | 1篇 |
无线电 | 2篇 |
一般工业技术 | 3篇 |
冶金工业 | 1214篇 |
自动化技术 | 13篇 |
出版年
2015年 | 2篇 |
2014年 | 4篇 |
2013年 | 6篇 |
2011年 | 2篇 |
2010年 | 2篇 |
2008年 | 2篇 |
2007年 | 1篇 |
2006年 | 6篇 |
2005年 | 2篇 |
2004年 | 1篇 |
2003年 | 5篇 |
2002年 | 2篇 |
2000年 | 1篇 |
1999年 | 29篇 |
1998年 | 391篇 |
1997年 | 205篇 |
1996年 | 147篇 |
1995年 | 66篇 |
1994年 | 61篇 |
1993年 | 73篇 |
1992年 | 6篇 |
1991年 | 19篇 |
1990年 | 11篇 |
1989年 | 22篇 |
1988年 | 13篇 |
1987年 | 12篇 |
1986年 | 11篇 |
1985年 | 10篇 |
1984年 | 1篇 |
1983年 | 1篇 |
1982年 | 7篇 |
1981年 | 9篇 |
1980年 | 6篇 |
1978年 | 2篇 |
1977年 | 36篇 |
1976年 | 77篇 |
1975年 | 2篇 |
1928年 | 1篇 |
1909年 | 1篇 |
1885年 | 4篇 |
排序方式: 共有1259条查询结果,搜索用时 31 毫秒
81.
SETTING: The activity of KRM 1648 (KRM), a new benzoxazinorifamycin, and rifabutin (RBT), alone or in combination with clarithromycin (CLA), was evaluated against Mycobacterium avium complex (MAC) that multiplied in human alveolar macrophages (AM). DESIGN: AM were recovered by bronchoalveolar lavage, incubated in RPMI 1640 medium with 10% human AB serum, infected with four strains of MAC (of non-acquired immune deficiency syndrome [AIDS] origin), and then treated with each drug alone or in combination. After incubation for 7 days, colony forming units in each well were counted on 7H10 agar. RESULTS: Although concentrations between 0.2 microgram/ml and 20 micrograms/ml of both rifamycins showed clear dose-dependent activities against all MAC strains tested, only 20 micrograms/ml of each drug had modest bactericidal effect. In combination with 2.0 micrograms/ml of CLA, however, 0.2 microgram/ml of both drugs caused a bactericidal response against two of the four MAC strains examined. CONCLUSION: According to this human alveolar macrophage model of MAC infection, KRM and RBT in combination with CLA was found to be a promising candidate against human pulmonary MAC infection, and deserves clinical evaluation. 相似文献
82.
83.
Oral appliances for the treatment of obstructive sleep apnea (OSA) produce either mandibular or tongue protrusion, and are thought to enlarge the upper airway (UA). We used videoendoscopy to measure UA cross-sectional area (CSA) and shape in the hypopharynx, oropharynx, and velopharynx during various stages of active mandibular and tongue protrusion during wakefulness in 10 patients with OSA and nine control subjects. Measurements were made in the supine position at end-tidal expiration, and were normalized to the CSA in the normal bite position. Airway shape was expressed as the anteroposterior/lateral (AP/L) diameter ratio. There were no differences between OSA patients and controls in the effects of mandibular and tongue protrusion on UA caliber. Both mandibular and tongue protrusion increased CSA in the hypopharynx and oropharynx (p < 0.001), whereas only tongue protrusion increased CSA in the velopharynx (p < 0.001). Tongue protrusion caused a greater increase in oropharyngeal and velopharyngeal CSA than did mandibular protrusion (p < 0.05). Mandibular protrusion caused a greater increase in CSA in the hypopharynx than in the oropharynx or velopharynx (p < 0.05). Obese patients had a larger relative increase in oropharyngeal CSA with mandibular and tongue protrusion than did subjects of normal weight. Tongue protrusion increased the AP/L diameter ratio in the oropharynx and velopharynx (p < 0.001), and mandibular protrusion did so to a lesser extent in the oropharynx (p < 0.01), resulting in a more circular airway shape. We conclude that mandibular and tongue protrusion increase the CSA and alter the shape of the UA during wakefulness. 相似文献
84.
V O'Connor C Heuss WM De Bello T Dresbach MP Charlton JH Hunt LL Pellegrini A Hodel MM Burger H Betz GJ Augustine T Sch?fer 《Canadian Metallurgical Quarterly》1997,94(22):12186-12191
The membrane protein syntaxin participates in several protein-protein interactions that have been implicated in neurotransmitter release. To probe the physiological importance of these interactions, we microinjected into the squid giant presynaptic terminal botulinum toxin C1, which cleaves syntaxin, and the H3 domain of syntaxin, which mediates binding to other proteins. Both reagents inhibited synaptic transmission yet did not affect the number or distribution of synaptic vesicles at the presynaptic active zone. Recombinant H3 domain inhibited the interactions between syntaxin and SNAP-25 that underlie the formation of stable SNARE complexes in vitro. These data support the notion that syntaxin-mediated SNARE complexes are necessary for docked synaptic vesicles to fuse. 相似文献
85.
86.
87.
88.
89.
MG DeCastro GA Denys LL Fauerbach JK Ferranti K Hawkins LC Masters D Rimland RJ Sharbaugh J Zeller 《Canadian Metallurgical Quarterly》1999,27(1):54-55
The Association for Professionals in Infection Control and Epidemiology, Inc (APIC), is a multidisciplinary, voluntary, international organization of professionals who practice infection control and the application of epidemiology in all health settings. APIC is an international leader in prevention and control of infection transmission. 相似文献
90.