Grain Floatation During Equiaxed Solidification of an Al-Cu Alloy in a Side-Cooled Cavity: Part I—Experimental Studies

Experimental studies were performed to investigate the role and influence of grain movement on macrosegregation and microstructure evolution during equiaxed solidification. Casting experiments were performed with a grain-refined Al-Cu alloy in a rectangular sand mold. For the aluminum alloy studied, the equiaxed grains are lighter than the bulk melt and thus float up. Experiments were designed to investigate floatation phenomena of equiaxed grains in the presence of thermosolutal convection. Cooling curves were recorded at key locations in both the casting and the chill. Quantitative image analysis and spatial chemical analysis were performed on the solidified casting to observe the chemical and microstructural inhomogeneity created by the melt convection and solid floatation. Several notable features that can be attributed to grain movement were observed in temperature histories, macrosegregation patterns, and microstructures. In our experiments, the floatation of grains influences the thermal conditions and the overall flow direction in the casting cavity. In some cases, the induced flow resulting from the grain movement caused a flow reversal. This in turn influences the solidification direction, microstructure evolution, and the overall macrosegregation behavior.     

Emulsifier Effects on Pasting Properties of Wheat Flour Extrudates with/without Sucrose and Shortening

The objective of this study was to determine the effects of emulsifier types and concentrations, plus the addition of sucrose and shortening on wheat flour extrudates. Ground extrudate pasting properties were measured in the rapid viscoanalyser (RVA). Four pasting parameters were determined from the RVA curve: peak time (PT), peak viscosity (P), breakdown viscosity (H), and initial slope (IS). Emulsifier types and the addition of sucrose and shortening significantly affected PT, P, H, and IS. Emulsifier concentration significantly influenced PT and H. Emulsifiers significantly increased PT and H and decreased P and IS. Glyceryl monostearate had the greatest effects on these parameters. Sucrose and shortening generally enhanced the effects of emulsifiers on pasting properties.     

Pre-adolescent children exhibit lower aerosol particle volume emissions than adults for breathing,speaking, singing and shouting

Speaking and singing are activities linked to increased aerosol particle emissions from the respiratory system, dependent on the utilized vocal intensity. As a result, these activities have experienced considerable restrictions in enclosed spaces since the onset of the COVID-19 pandemic due to the risk of infection from the SARS-CoV-2 virus, transmitted by virus-carrying aerosols. These constraints have affected public education and extracurricular activities for children as well, from in-person music instruction to children’s choirs. However, existing risk assessments for children have been based on emission measurements of adults. To address this, we measured the particle emission rates of 15 pre-adolescent children, all eight to ten years old, with a laser particle counter for the test conditions: breathing at rest, speaking, singing and shouting. Compared with values taken from 15 adults, emission rates for breathing, speaking and singing were significantly lower for children. Particle emission rates were reduced by a factor of 4.3 across all conditions, whereas emitted particle volume rates were reduced by a factor of 4.8. These data can supplement SARS-CoV-2 risk management scenarios for various school and extracurricular settings.     

Benchmarking advanced architecture computers

Recently, a number of advanced architecture machines have become commercially available. These new machines promise better cost performance than traditional computers, and some of them have the potential of competing with current supercomputers, such as the CRAY X-MP, in terms of maximum performance. This paper describes the methodology and results of a pilot study of the performance of a broad range of advanced architecture computers using a number of complete scientific application programs. The computers evaluated include:

• 1 shared-memory bus architecture machines such as the Alliant FX/8, the Encore Multimax, and the Sequent Balance and Symmetry
• 2 shared-memory network-connected machines such as the Butterfly
• 3 distributed-memory machines such as the NCUBE, Intel and Jet Propulsion Laboratory (JPL)/Caltech hypercubes
• 4 very long instruction word machines such as the Cydrome Cydra-5
• 5 SIMD machines such as the Connection Machine
• 6 ‘traditional’ supercomputers such as the CRAY X-MP, CRAY-2 and SCS-40.

Seven application codes from a number of scientific disciplines have been used in the study, although not all the codes were run on every machine. The methodology and guidelines for establishing a standard set of benchmark programs for advanced architecture computers are discussed. The CRAYs offer the best performance on the benchmark suite; the shared memory multiprocessor machines generally permitted some parallelism, and when coupled with substantial floating point capabilities (as in the Alliant FX/8 and Sequent Symmetry), provided an order of magnitude less speed than the CRAYs. Likewise, the early generation hypercubes studied here generally ran slower than the CRAYs, but permitted substantial parallelism from each of the application codes.     

Quantum Mechanics and Molecular Dynamics Calculations provide new evidence for a free-radical shock initiation model

The contrast between a hydrodynamic model for shock initiation of explosives and a newer microscopic free-radical model is presented. The primary considerations of the free-radical model are that shock energy is very coherent and that it is strong enough to cause mechanical fracture of covalent bonds. The shock front on a microscopic scale is very narrow (∼5 Å to 15 Å) and thermal equilibrium does not exist in the front. The free atoms and radicals formed by the shear and acceleration forces in the shock front initiate the chemical reaction that leads to hot spots and the eventual decomposition of the explosive materials. Energy-release rates and vibrational velocities of the covalently bound atoms are factors in establishing detonation velocities. A number of explosives phenomena are discussed as the new model provides explanations for them. New information from molecular dynamics and quantum mechanical calculations on shock waves in condensed systems and recent experimental data are shown to support the free-radical model.     

Food allergy,a summary of eight cases in the UK criminal and civil courts: effective last resort for vulnerable consumers?

Food allergy has a forensic context. The authors describe eight cases in the UK courts involving fatalities, personal injury or criminal non‐compliance with food law from mainly ‘grey’ literature sources. The potentially severe consequences for people with food allergy of contraventions of labelling law have led to enforcement action up to criminal prosecution for what might otherwise be regarded as ‘trivial’ non‐compliance. The authors suggest there should be central collation of such cases. Non‐compliances should be followed up in a more rapid and robust manner. Evidence of fraud in the catering supply chain supports recent calls for zero tolerance of food fraud. Businesses must guard against gaps in allergen management, for which there are readily available sources of training and guidance, but also against fraudulent substitution in the supply chain, about which training and guidance should be developed. New allergen labelling legislation and case law appear to place responsibility on food businesses even for the forensically problematic area of allergen cross‐contamination. The courts can be an effective last resort for vulnerable consumers; however, there is evidence of knowledge and skill gaps in both the investigation and prosecution of potentially serious incidents of food allergen mismanagement and mislabelling. Thorough investigation of food allergy deaths is required with a tenacious and skilled approach, including early realisation that samples of the food and/or stomach contents from a post mortem examination should be retained and analysed. The supply chain must be rigorously examined to find out where adulteration or contamination with the fatal allergen occurred. © 2014 Society of Chemical Industry     

Far-off and close-up dry matter intake modulate indicators of immunometabolic adaptations to lactation in subcutaneous adipose tissue of pasture-based transition dairy cows

The common practice of increasing dietary energy density during the close-up dry period (last ～3 wk prepartum) has been recently associated with a higher incidence of metabolic disorders after calving. Despite these reports, over-feeding of metabolizable energy (ME) during the far-off, nonlactating period is a common management policy aimed at achieving optimum calving body condition score (BCS) in pasture-based systems, as cows are generally thinner than total mixed ration cows at the end of lactation. Our hypothesis was that both far-off and close-up overfeeding influence the peripartum adipose tissue changes associated with energy balance and inflammatory state. Sixty mid-lactation, grazing dairy cows of mixed age and breed were randomly allocated to 1 of 2 groups that were managed through late lactation to achieve a low and high BCS (approximately 4.25 and 5.0 on a 10-point scale) at dry-off. The low BCS cows were then overfed ME to ensure that they achieved the same BCS as the higher BCS group by calving. Within each rate of BCS gain treatment, cows were offered 65, 90, or 120% of their pre-calving ME requirements for 3 wk pre-calving in a 2 × 3 factorial arrangement of treatments (i.e., 10 cows/treatment). Subcutaneous adipose tissue was collected via biopsy at ?1, 1, and 4 wk relative to parturition. Quantitative PCR was used to measure mRNA and microRNA expression of targets related to adipogenesis and inflammation. Cows overfed in the far-off period had increased expression of miR-143 and miR-378 prepartum (?1 wk) indicating greater adipogenesis, consistent with their rapid gain in BCS following dry-off. Furthermore, the lower postpartum expression of IL6, TNF, TLR4, TLR9, and miR-145, and a higher abundance of miR-99a indicated lower body fat mobilization in early lactation in the same group. In the close-up period, feeding either 65 or 120% of ME requirements caused changes in FASN, IL1B, IL6R, TLR9, and the microRNA miR-143, miR-155, and miR-378. Their respective expression patterns indicate a tentative negative-feedback mechanism in metabolically compromised, feed-restricted cows, and a possible immune-related stimulation of lipolysis in apparently static adipocytes in overfed cows. Data from cows fed 90% of ME requirements indicate the existence of a balance between lipolytic (inflammatory-related) and anti-lipolytic signals, to prime the mobilization machinery in light of imminent lactation. Overall, results indicate that far-off dry cow nutrition influences peripartum adipose tissue metabolism, with neither strategy negatively affecting the physiological adaptation to lactation. Furthermore, to ensure a favorable transition, cows should be subjected to a small feed restriction in the close-up period, irrespective of far-off nutritional management.