A New Hand-Held Microsystem Architecture for Biological Analysis

This paper presents a hand-held microsystem based on new fully integrated magnetoresistive biochips for biomolecular recognition (DNA hybridization, antibody antigen interaction, etc.). Magnetoresistive chip surfaces are chemically treated, enabling the immobilization of probe biomolecules such as DNA or antibodies. Fluid handling is also integrated in the biochip. The proposed microsystem not only integrates the biochip, which is an array of 16times16 magnetoresistive sensors, but it also provides all the electronic circuitry for addressing and reading out each transducer. The proposed architecture and circuits were specifically designed for achieving a compact, programmable and portable microsystem. The microsystem also integrates a hand-held analyzer connected through a wireless channel. A prototype of the system was already developed and detection of magnetic nanoparticles was obtained. This indicates that the system may be used for magnetic label based bioassays     

CSTN-LCD用铬版清洗效果的改善

利用铬版清洗机对CSTN-LCD用铬版进行清洗处理,分析了清洗过程中出现的铬层脱落现象,铬层脱落与轴向喷射压力和水平切力密切相关,通过调整转速和喷射压力探索了安全使用条件:在转速不超过1000r/min,喷射压力低于0.5×105Pa的情况下使用铬版清洗机进行清洗是相对安全的。同时采用预清洗处理的方法满足清洁要求,使换线时间由平均3h缩短到平均1h以内,年产能提高270000片。     

L’optimisation des réseaux cellulaires assistée par ordinateur: le logiciel RNO (Radio Network Optimisation)

Quality of service has become today a major concern for operators of mobile communication networks. The massive development of networks and strong competition between operators has lead to the necessary and daily follow-up of network quality of service, a key factor for its subscriber’s fidelity. This article aims at presenting the optimization methodology and proposes its illustration with a case of RNO (Radio Network Optimisation) software usage, one of the Alcatel optimization toolchain component. After a short presentation of cellular network, the optimization basic principles are described. RNO software and its main functionnalities are then detailed before a last part dedicated to a real case of optimization done with RNO software.     

地杂波O．94μm激光后向反射率测试研究

通过对地杂波O．94μm激光后向反射率的测试，获取不同入射角的多背景后向反射率测试数据。通过对测试数据的分析处理提供特征信息，为激光探浏器设计提供依据。     

草酸钙在硫酸软骨素自组装膜上周期沉淀的研究

利用硫酸软骨素(chondroitin sulfate，CS)在云母基底上通过浇铸法制备的自组装膜为基底，诱导草酸钙在其上的凝集生长。发现当硫酸软骨素的浓度为1．Omg／ml时在该膜体系中可形成规整的周期性草酸钙环状沉淀。这种有序的环状结构可能是耗散结构的一种具体表现形式。利用原子力显微镜(atomic forcemicroscope，AFM)和傅立叶红外光谱仪对这种结构进行了表征，实验结果显示合适浓度下形成的CS膜在一定程度上可以抑制草酸钙的凝集结晶，表明高分子基质与无机离子间强烈的相互作用对无机盐的成核结晶有显著影响，为探讨结石的形成与抑制提供了一定的实验依据。     

双转向垂向控缝技术实验研究及现场应用

针对压裂过程中缝高较难控制的问题，研制开发出新型的油溶性垂向双转向剂，并开展了室内实验研究。首次验证了转向剂对裂缝延伸的控制机理，确定了转向剂的适用浓度及控缝能力。实验表明，转向剂可以增加隔层应力3～4MPa左右。在此基础上研究了控制裂缝高度施工方案的设计方法，并利用全三维软件结合垂向应力剖面对控缝技术进行了优化。现场推广应用30井次，取得了较好的控缝效果。     

美国固体照明技术进展概况

介绍了美国能源部于2002年开始实施的固体照明(SSL)技术的"下一代照明计划".同时对美国SSL技术的研发、生产和使用现状以及召开学术会议的情况做了叙述.     

Enhancing both network and user performance for networks supporting best effort traffic

With a view on improving user-perceived performance on networks supporting best effort flows, e.g., multimedia/data file transfers, we propose a family of bandwidth allocation criteria that depends on the residual work of on-going transfers. Analysis and simulations show that allocating bandwidth in this fashion can significantly improve the user-perceived delay, bit transmission delay, and throughput over traditional approaches, e.g., by 58% on an 80% loaded linear network. A simple implementation based on TCP Reno, exemplifies how one might approach practically realizing such gains. We discuss several other advantages of incorporating such differentiation at the transport level. In particular we make the case that favoring small transfers combined with user impatience or peak rate constraints, both of which are natural mechanisms for users to express the utility of completing transfers, offers a lightweight approach to achieving good overall network goodput and/or utility for best effort networks.     

用于高频谐振器的PbTiO_3基压电陶瓷

传统的PZT压电陶瓷的相对介电常数较大,一般为1 000以上,用于高频谐振器不易与线路匹配;而PbTiO3基压电陶瓷的相对介电常数较小,一般仅为200左右,对于10 MHz以上频率的谐振器,用PbTiO3基压电陶瓷作为压电振子是最佳的选择。本文主要研究用于高频谐振器的MnO2和Nd2O3改性PbTiO3基压电陶瓷的性质。PbTiO3基压电陶瓷的性质的改善是与此种陶瓷的制备工艺,显微结构和电导机制紧密相关的。     

Viral dynamics of primary viremia and antiretroviral therapy in simian immunodeficiency virus infection

Mathematical modeling of viral replication dynamics, based on sequential measurements of levels of virion-associated RNA in plasma during antiretroviral treatment, has led to fundamental new insights into human immunodeficiency virus type 1 pathogenesis. We took advantage of the simian immunodeficiency virus (SIV)-infected macaque model to perform detailed measurements and mathematical modeling during primary infection and during treatment of established infection with the antiretroviral drug (R)-9-(2-phosphonylmethoxypropyl)adenine (PMPA). The calculated clearance half-life for productively infected cells during resolution of the peak viremia of primary infection was on the order of 1 day, with slightly shorter clearance half-lives calculated during PMPA treatment. Viral reproduction rates upon discontinuation of PMPA treatment after 2 weeks were approximately twofold greater than those obtained just prior to initiation of treatment in the same animals, likely reflecting accumulation of susceptible target cells during treatment. The basic reproductive ratio (R0) for the spread of SIV infection in vivo, which represents the number of productively infected cells derived from each productively infected cell at the beginning of infection, was also estimated. This parameter quantifies the extent to which antiviral therapy or vaccination must limit the initial spread of virus to prevent establishment of chronic disseminated infection. The results thus provide an important guide for efforts to develop vaccines against SIV and, by extension, human immunodeficiency virus.