Lesions of the tracheobronchial tree after the aspiration of a tablet of ferrous sulfate

Foreign body aspiration requires emergency bronchoscopic examination when the product is chemically active. We describe the case of a female patient who aspirated a ferrous sulfate tablet that, in spite of being extracted immediately, caused lesions that persisted in the bronchial tree for 6 weeks. We then discuss the potential of ferrous sulfate substance to cause damage to the tracheobronchial tree.     

Observations on Federal energy research and development—December 1974

Much of our country's present stance in energy R&D is an embodiment of the recommendations presented in the Dixy Lee Ray report, “The Nation's Energy Future” (NEF).^Pa Since that report appeared just one year ago, the Energy Research and Development Administration (ERDA)^∥ has been established, and the Project Independence Blueprint (PIB)¹¹     

Flavor reversion in soybean oil

Summary A simulated soybean oil has been synthesized from purified fatty acids. The flavor characteristics of the oil after heat and light treatment are described and compared to those of soybean and cottonseed oils. The generous financial assistance of the National Association of Margarine Manufactures is gratefully acknowledged. Contribution No. 613 from the Department of Chemistry, University of Pittsburgh.     

Activation of cysteine proteases in cowpea plants during the hypersensitive response--a form of programmed cell death

The matrix metalloproteinases appear to play a key role in mammary tissue remodeling during involution. By immunoprecipitation and immunoblot using antibodies against 60K gelatinase which appears during involution a 90K polypeptide has been identified as its inactive proenzyme in the early involuting rat mammary gland. 90K polypeptide was isolated from the second day involuting rat mammary gland by immunoaffinity chromatography. On proteolytic digestion, the inactive 90K polypeptide was converted to active gelatinase. Primary cultures of mammary epithelial cells secreted the 90K polypeptide. These results indicated that the 60K inducible MMP involved in mammary gland involution and remodeling is produced as a 90K proenzyme which is activated by proteolysis in the extracellular sites.