全文获取类型
收费全文 | 2904篇 |
免费 | 27篇 |
国内免费 | 3篇 |
专业分类
电工技术 | 12篇 |
综合类 | 1篇 |
化学工业 | 76篇 |
金属工艺 | 6篇 |
机械仪表 | 20篇 |
建筑科学 | 21篇 |
矿业工程 | 6篇 |
能源动力 | 7篇 |
轻工业 | 46篇 |
水利工程 | 2篇 |
石油天然气 | 1篇 |
无线电 | 102篇 |
一般工业技术 | 86篇 |
冶金工业 | 2479篇 |
自动化技术 | 69篇 |
出版年
2021年 | 4篇 |
2020年 | 10篇 |
2019年 | 3篇 |
2018年 | 11篇 |
2017年 | 9篇 |
2016年 | 14篇 |
2015年 | 10篇 |
2014年 | 17篇 |
2013年 | 21篇 |
2012年 | 14篇 |
2011年 | 26篇 |
2010年 | 15篇 |
2009年 | 12篇 |
2008年 | 15篇 |
2007年 | 15篇 |
2006年 | 14篇 |
2005年 | 10篇 |
2004年 | 16篇 |
2003年 | 9篇 |
2002年 | 8篇 |
2001年 | 15篇 |
2000年 | 13篇 |
1999年 | 100篇 |
1998年 | 779篇 |
1997年 | 490篇 |
1996年 | 297篇 |
1995年 | 172篇 |
1994年 | 126篇 |
1993年 | 174篇 |
1992年 | 24篇 |
1991年 | 23篇 |
1990年 | 34篇 |
1989年 | 24篇 |
1988年 | 21篇 |
1987年 | 23篇 |
1986年 | 25篇 |
1985年 | 27篇 |
1984年 | 3篇 |
1983年 | 8篇 |
1982年 | 20篇 |
1981年 | 18篇 |
1980年 | 24篇 |
1979年 | 11篇 |
1978年 | 9篇 |
1977年 | 67篇 |
1976年 | 124篇 |
1975年 | 4篇 |
1968年 | 3篇 |
1966年 | 3篇 |
1955年 | 4篇 |
排序方式: 共有2934条查询结果,搜索用时 15 毫秒
51.
AV Susekov MG Tvorogova GG Arabidze VV Kukharchuk 《Canadian Metallurgical Quarterly》1998,70(9):57-61
AIM: The study of the hypolipidemic efficiency, safety and tolerance of ciprofibrate (lipanor) in therapy of atherogenic hyperlipoproteinemia. MATERIALS AND METHODS: The trial included 14 hypertensive postmenopausal females, 14 patients with diabetes mellitus type II, 14 males with coronary heart disease and primary hyperlipoproteinemia (total cholesterol > 6.5 mmol/l, triglycerides < 4.5 mmol/l under low-cholesterol diet). Lipanor was given for 12 weeks in a daily single dose 100 mg in the morning. Lipids and other biochemical indices were measured in a fasting state after 1 and 3 months of lipanor treatment. RESULTS: After 1 month of lipanor treatment there was a 22-30%, 24-49% decrease in the level of low-density lipoprotein cholesterol, triglycerides, respectively. High-density lipoprotein cholesterol increased by 16%. The hypolipidemic effect of lipanor persisted for 3 months during which triglycerides continued to fall (up to 38.5%). Lipanor was well tolerated, only one patient with diabetes mellitus had hyperactivity of creatine phosphokinase manifesting with clinical symptoms (the drug was discontinued). 3 patients developed mild side effects. Alkaline phosphatase activity inhibited in all the groups by 25-41%. CONCLUSION: Lipanor is a highly effective, safe hypolipidemic drug with good tolerance. It can be recommended for correction of atherogenic hyperlipoproteinemia in patients at high risk of atherosclerosis progression. 相似文献
52.
A 74-year-old patient sought treatment for visual obscuration and clinically had signs of Graves orbitopathy. Past medical history was unremarkable except for the use of antihypertensive medication. During the hospital admission, a fluorescent treponemal antibody absorption test was reactive, indicating infection with syphilis at some time in the past. Visual deterioration despite oral corticosteroid therapy prompted orbital decompression. At the time of surgery, she sustained a globe rupture. Presumably, syphilitic scleritis was responsible, in part, for scleral thinning and weakening, predisposing her to this complication. To the authors' knowledge, globe rupture has not been previously reported during orbital decompression. 相似文献
53.
54.
J Sayos C Wu M Morra N Wang X Zhang D Allen S van Schaik L Notarangelo R Geha MG Roncarolo H Oettgen JE De Vries G Aversa C Terhorst 《Canadian Metallurgical Quarterly》1998,395(6701):462-469
In addition to triggering the activation of B- or T-cell antigen receptors, the binding of a ligand to its receptor at the cell surface can sometimes determine the physiological outcome of interactions between antigen-presenting cells, T and B lymphocytes. The protein SLAM (also known as CDw150), which is present on the surface of B and T cells, forms such a receptor-ligand pair as it is a self-ligand. We now show that a T-cell-specific, SLAM-associated protein (SAP), which contains an SH2 domain and a short tall, acts as an inhibitor by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region. The gene encoding SAP maps to the same area of the X chromosome as the locus for X-linked lymphoproliferative disease (XLP) and we found mutations in the SAP gene in three XLP patients. Absence of the inhibitor SAP in XLP patients affects T/B-cell interactions induced by SLAM, leading to an inability to control B-cell proliferation caused by Epstein-Barr virus infections. 相似文献
55.
KK Khurana MG Kivelson DJ Stevenson G Schubert CT Russell RJ Walker C Polanskey 《Canadian Metallurgical Quarterly》1998,395(6704):777-780
The Galileo spacecraft has been orbiting Jupiter since 7 December 1995, and encounters one of the four galilean satellites-Io, Europa, Ganymede and Callisto-on each orbit. Initial results from the spacecraft's magnetometer have indicated that neither Europa nor Callisto have an appreciable internal magnetic field, in contrast to Ganymede and possibly Io. Here we report perturbations of the external magnetic fields (associated with Jupiter's inner magnetosphere) in the vicinity of both Europa and Callisto. We interpret these perturbations as arising from induced magnetic fields, generated by the moons in response to the periodically varying plasma environment. Electromagnetic induction requires eddy currents to flow within the moons, and our calculations show that the most probable explanation is that there are layers of significant electrical conductivity just beneath the surfaces of both moons. We argue that these conducting layers may best be explained by the presence of salty liquid-water oceans, for which there is already indirect geological evidence in the case of Europa. 相似文献
56.
Hemispheric contributions to the integration of visual and auditory information in speech perception
Differential hemispheric contributions to the perceptual phenomenon known as the McGurk effect were examined in normal subjects, 1 callosotomy patient, and 4 patients with intractable epilepsy. Twenty-five right-handed subjects were more likely to demonstrate an influence of a mouthed word on identification of a dubbed acoustic word when the speaker's face was lateralized to the LVF as compared with the RVF. In contrast, display of printed response alternatives in the RVF elicited a greater percentage of McGurk responses than display in the LVF. Visual field differences were absent in a group of 15 left-handed subjects. These results suggest that in right-handers, the two hemispheres may make distinct contributions to the McGurk effect. The callosotomy patient demonstrated reliable McGurk effects, but at a lower rate than the normal subjects and the epileptic control subjects. These data support the view that both the right and left hemisphere can make significant contributions to the McGurk effect. 相似文献
57.
Henry J. Pownall Joel D. Morrisett James T. Sparrow Louis C. Smith James Shepherd Richard L. Jackson Antonio M. Gotto Jr. 《Lipids》1979,14(4):428-434
The human plasma high density lipoproteins (HDL) are a heterogeneous ensemble of five proteins associated with both neutral
and polar lipids. The sequences of all five proteins are known. ApoA-I and apoA-II are the major protein components; apoC-I,
apoC-II and apoC-III are the minor protein components. All these apoproteins spontaneously recombine with phospholipids to
give stable lipid-protein complexes and freely exchange between the two major HDL subclasses, HDL2 and HDL3. In addition, ApoC-I, apoC-II, and apoC-III exchange between HDL and very low density lipoproteins. Furthermore, certain
HDL apoproteins are activators for plasma enzymes that are important in lipid metabolism. ApoA-I and apoC-I activate lecithin/cholesterol
acyltransferase; apoC-II is an activator of lipoprotein lipase. The regions of apoC-I and apoC-II that are involved in the
activation of these enzymes have been localized with synthetic peptides. Studies of synthetic and native fragments of apoA-II,
apoC-I, apoC-II, and apoC-III as well as model lipid-binding peptides have identified specific regions with structural features
common to lipid-binding proteins. These special properties, which include helical potential, sequences with a critical amphipathic
length, and high hydrophobicity of the nonpolar side of the amphipathic helix, are the determinants of HDL structure and metabolism. 相似文献
58.
RD Jones AR Visram JP Kornberg MG Irwin WM Gunawardene 《Canadian Metallurgical Quarterly》1994,22(5):539-544
We studied 30 children, aged 4 to 12 years, undergoing elective circumcision, premedicated with midazolam 0.5 mg.kg-1 and atropine 0.02 mg.kg-1 by mouth. A modified postbox test and the coding component of the Wechsler intelligence scale (WISC-R) was used to assess the preoperative effect of premedication on psychomotor function. Mood and sedation were also scored and related to serum midazolam concentrations. The children showed a significant decline in psychomotor performance 30 and 60 minutes after premedication when compared with their best unmedicated performance recorded the previous evening. This decline in psychomotor performance was only weakly associated with serum midazolam concentrations (r = 0.1). The postbox toy ratio is a suitable measurement of psychomotor performance in children because of its simplicity and ease of use in the clinical environment, although it may suffer the "test-retest" limitations of similar types of assessment. The sedative and anxiolytic effects of midazolam provide a quiet environment for a smooth induction of anaesthesia. 相似文献
59.
60.
R Coppo MG Porcellini R Bonaudo L Peruzzi A Amore G Conti 《Canadian Metallurgical Quarterly》1998,11(4):171-176
The progressive loss of renal function in children with chronic renal failure (CRF) has a negative influence on their nutritional status and statural growth. Supportive therapies with 1-25 dihydroxy-vitamin D3, recombinant erythropoietin and growth hormone have significantly improved the biochemical and clinical features but the success of these therapies is largely related to an appropriate diet, with adequate protein/caloric intakes. Children more than adults have minimal protein requirements to avoid malnutrition and growth impairment FAO/WHO and RDA recommendations save as guidelines for a correct diet in children with CRF. Following these allowances leads to a "normoproteic" diet, with a protein intake which is often half the unrestricted one in Western European countries, but which is still likely to be not enough to protect against renal deterioration. Indeed the European Study Group for Nutritional Treatment of CRF in children failed to show a significant effect of diet on the mean decline of glomerular filtration rate over two years. 相似文献