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71.
V. G. Volkov D. N. Dem’yanov 《Optoelectronics, Instrumentation and Data Processing》2016,52(4):334-340
It is shown that the problem of observer design for estimating a set of linear combinations of state variables of a plant can be formulated in terms of linear matrix inequalities. An algorithm for constructing functional observers is proposed based on a nonsingular transformation of a plant model in the state space by matrix canonization with subsequent solution of the system of linear matrix inequalities. 相似文献
72.
Ustinov V. S. Volkov A. N. Samoilov O. B. Morozov O. A. Polyanskikh S. A. Alekseev V. I. Galitskikh V. Yu. 《Atomic Energy》2021,130(2):69-75
Atomic Energy - The physical aspects and main results of reactor tests of a two-stage core consisting of fresh fuel assemblies and a significant number of fuel assemblies from the previous core,... 相似文献
73.
74.
V. G. Volkov A. G. Volkovich V. I. Pavlenko S. V. Smirnov A. V. Chesnokov A. E. Arustamov E. I. Veselov D. R. Vasendin 《Atomic Energy》2009,107(4):277-283
The results of an examination of objects and grounds of the Kirovo-Chepetsk Chemical Works are presented. The methods used
to perform a radiation survey are described briefly. The data obtained are used as a basis for a concept of rehabilitation
of radioactively contaminated objects and grounds of the works. The radwaste volumes are determined for each object and possible
ways to handle them are proposed. The technologies for handling radwastes are examined. The primary problems that must be
solved without delay are determined. 相似文献
75.
A. V. Shchagin V. I. Volkov V. S. Miroshnik A. S. Kubankin A. N. Oleinik 《Technical Physics Letters》2018,44(1):47-49
The properties of X-ray emission from a pyroelectric accelerator based on ferroelectric ceramics have been experimentally studied, including the maximum energy of X-ray photons and their maximum yield generated by accelerated electrons at various pressures of residual gas in the generator chamber. The maximum X-ray yield and maximum energy of X-ray photons and accelerated electrons have been observed at a residual-gas pressure of around several millitorr. 相似文献
76.
Semiconductors - In the paper the test data on new cycle-resistant thermoelectric modules are presented and discussed. These modules can be applied in medical equipment for polymerase chain... 相似文献
77.
M Mirshahi S Mirshahi N Golestaneh C Nicolas Z Mishal MK Agarwal 《Canadian Metallurgical Quarterly》1998,24(3-4):455-459
A Cell extract from the HEL (human erythroblastic leukemia) cell line was positive for both the epithelial sodium channel (ENaC) and the mineralocorticoid receptor (MCR) as glycosylated 82-84 kDa bands, and a single 102 kDa band, respectively, in Western blots using polyclonal antibodies raised against these proteins. The immunofluorescent labeling of the MCR in all cell lines showed a nucleocytoplasmic localization of the receptor whereas the ENaC was exclusively membrane-bound. These results were confirmed by confocal microscopy. The expression of the MCR in HEL cells was evident as a predicted band of 843 bp (234 amino acids) after total RNA from HEL cells had been reverse transcribed and then amplified by PCR; the ENaC was similarly evident as a predicted band of 520 bp. In both cases, near 100% identity was observed between the deduced amino acid sequences of the PCR products and those from known human sources. The multiplication of HEL cells was influenced by antagonists (RU 26752, ZK 91587) targeted for specificity to the MCR and this was reversed by the natural hormone aldosterone. These steroids also provoked chromatin condensation in the HEL population. 相似文献
78.
VN Bhattathiri L Bindu P Remani B Chandralekha CA Davis MK Nair 《Canadian Metallurgical Quarterly》1996,41(2):139-142
The role of the propeptide sequence and a disulfide bridge between sites 1 and 122 in chymotrypsin has been examined by comparing enzyme activities of wild-type and mutant enzymes. The kinetic constants of mutants devoid of the Cys1-Cys122 disulfide-linked propeptide show that this linkage is not important either for activity or substrate specificity. However this linkage appears to be the major factor in keeping the zymogen stable against non-specific activation. A comparison of zymogen stabilities showed that the trypsinogen propeptide is ten times more effective than the chymotrypsinogen propeptide in preventing non-specific zymogen activation during heterologous expression and secretion from yeast. This feature can also be transferred in trans to chymotrypsinogen; i.e. the chymotrypsin trypsin propeptide chimera forms a stable zymogen. 相似文献
79.
MK Bolla GJ Miller DM Yellon A Evans G Luc JP Cambou D Arveiler F Cambien DS Latchman SE Humphries IN Day 《Canadian Metallurgical Quarterly》1998,13(4):227-235
In 12 depressed inpatients referred for bilateral electroconvulsive therapy (ECT), each patient was titrated at the first treatment session by using an ascending method-of-limits procedure with a step-wise increase in pulse frequency (frequency titration) or train duration (duration titration). At the second treatment session, seizure threshold was redetermined by using the method (frequency or duration titration) not used at the first treatment. Frequency or duration was maintained at the lowest level when the other parameter was titrated. Seizure threshold was significantly lower with duration titration (mean, 90 mC; SD, 27.3) than frequency titration (mean, 114 mC; SD, 35.6; p = 0.03). On average, patients in the duration-titration group required 1.2 (SD, 0.6) subconvulsive stimulations before a seizure was elicited, and patients in the frequency-titration group required 1.7 (SD, 0.9) subconvulsive stimulations before a seizure was elicited, a nonsignificant difference. These findings suggest that to elicit a seizure during ECT, increasing train duration may be slightly more efficient than increasing frequency. Basic and other clinical research findings indicate that increasing pulse width may be an inefficient way to elicit a seizure. Therefore the following sequence in the determination of seizure threshold is worth considering when using dose-titration or related techniques: the train duration should be increased first before increasing pulse frequency, and the decision to increase pulse width should be reserved for patients who do not seize at the maximal duration and frequency settings. Further empiric research is needed to establish the utility of this approach. 相似文献
80.
Our previous studies in iron-loaded rat heart cells showed that in vitro iron loading results in peroxidative injury, manifested in a marked decrease in rate and amplitude of heart cell contractility and rhythmicity, which is correctable by treatment with deferoxamine (DF). In the present studies we explored the role of mitochondrial damage in myocardial iron toxicity. Iron loading by 24-hour incubation with 0.36 mmol/L ferric ammonium citrate resulted in a decrease in the activity of nicotinamide adenine dinucleotide (NADH)-cytochrome c oxidoreductase (complex I+III) to 35.3%+/-11.2% of the value in untreated controls; of succinate-cytochrome c oxidoreductase (complex II+III) to 57.4%+/-3.1%; and of succinate dehydrogenase to 63.5%+/-12.6% (p < 0.001 in all cases). The decrease in activity of other mitochondrial enzymes, including NADH-ferricyanide reductase, succinate ubiquinone oxidoreductase (complex II), cytochrome c oxidase (complex IV), and ubiquinol cytochrome c oxidoreductase (complex III), was less impressive and ranged from 71.5%+/-15.8% to 91.5%+/-14.6% of controls. That the observed loss of respiratory enzyme activity was a specific effect of iron toxicity was clearly demonstrated by the complete restoration of enzyme activities by in vitro iron chelation therapy. Sequential treatment with iron and doxorubicin caused a loss of complex I+III and complex II+III activity that was greater than that seen with either agent alone but was only partially correctable by DF treatment. Alterations in cellular adenosine triphosphate measurements paralleled very closely the changes observed in respiratory complex activity. These findings demonstrate for the first time the impairment of cardiac mitochondrial respiratory enzyme activity caused by iron loading at conditions formerly shown to produce severe abnormalities in contractility and rhythmicity. 相似文献