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71.
Repositories remain an innovative but marginalised technology largely because there is no consensus about an agreed set of Performance Indicators (PIs) that demonstrate their overall impact on the research enterprise of our universities. A successful institutional repository (IR) should be evaluated in terms of the extent to which the open access repository builds a critical mass of scholarly content which is sustained and available through active university community engagement and ongoing scholarly contributions (faculty, researchers and students) that, when managed efficiently and effectively, ultimately strengthen, promote and give visibility to the research enterprise of the institution, and bring benefit to broader society. However, librarians are grappling with what and how best to demonstrate ‘institutional good’ but without clear evidence, assessment is fed by perception based on limited information which leads to diminished impact and value of the facility, a tyranny described as being caught between a rock and a hard place. Using Illuminative Evaluation to design a series of quantitative and qualitative metrics, it is proposed that a distinction be made between significant and secondary PIs where the former gather evidence to demonstrate the overall effect or impact of the IR on the individual and collective research community.  相似文献   
72.
OBJECTIVE: To investigate the relationship among friction, applied torque, and axial push force on cylindrical handles. BACKGROUND: We have earlier demonstrated that participants can exert greater contact force and torque in an "inward" movement of the hand about the long axis of a gripped cylinder (wrist flexion/forearm supination) than they can in an "outward" hand movement. METHOD: Twelve healthy participants exerted anteriorly directed maximum push forces along the long axis of aluminum and rubber handles while applying deliberate inward or outward torques, no torque (straight), and an unspecified (preferred) torque. RESULTS: Axial push force was 12% greater for the rubber handle than for the aluminum handle. Participants exerted mean torques of 1.1, 0.3, 2.5, and -2.0 Nm and axial push forces of 94, 85, 75, and 65 N for the preferred, straight, inward, and outward trials, respectively. Left to decide for themselves, participants tended to apply inward torques, which were associated with increased axial push forces. CONCLUSION: Axial push force was limited by hand-handle coupling--not the whole body's push strength. Participants appeared to intuitively know that the application of an inward torque would improve their maximum axial push force. Axial push forces were least when a deliberate torque was requested, probably because high levels of torque exertions interfered with the push. APPLICATION: A low-friction handle decreases maximum axial push force. It should be anticipated that people will apply inward torque during maximum axial push.  相似文献   
73.
The Companion cognitive architecture supports experiments in achieving human-level intelligence. This article describes seven key design goals of Companions, relating them to properties of human reasoning and learning, and to engineering concerns raised by attempting to build large-scale cognitive systems. We summarize our experiences with Companions in two domains: test taking and game playing.  相似文献   
74.
75.
The ageing response of 2124 Al-SiC particulate metal-matrix composite (MMC) and unreinforced alloy has been examined using hardness measurements and Arrhenius analysis. The formation of phases during precipitation has been studied using differential scanning calorimetry (DSC). The MMC exhibits accelerated ageing compared to unreinforced alloy, due to enhanced S formation. The activation energy for diffusion is lower in the MMC than in the unreinforced alloy. DSC scans show Guinier-Preston B (GPB) zone nucleation to occur at a lower temperature in the MMC, whilst the total volume of GPB zones formed is smaller than in the unreinforced alloy. A model has been proposed to explain the GPB zone formation behaviour, in which ease of GPB zone nucleation varies within the MMC, as a function of ageing time and of position within the matrix. S formation is enhanced in the MMC because of improved diffusion and a large increase in density of heterogeneous nucleation sites compared to the unreinforced alloy.  相似文献   
76.
Adsorption isotherms for sodium and trivalent chromium uptake from aqueous solutions onto Amberlite resin were prepared at 18°C. Adsorption of each cation followed the Langmuir model. The rate of uptake of each cation was found to be film diffusion controlled with sodium showing the most rapid uptake. In aqueous solutions containing both chromium and sodium as the only cationic species, it was found that with increasing initial concentration of sodium, the trivalent chromium uptake on the resin decreased substantially. To overcome this difficulty a four step redox–adsorption system has been developed for the removal of Cr3+ from tannery effluents. The first step comprises the oxidation of trivalent chromium to the hexavalent form using selected common oxidising agents. The liquid effluent is then passed through an Amberlite cation-exchange resin in step 2 where the sodium in the waste stream is completely removed. The anionic hexavalent form of chromium (Cr2O) passes unaltered through the resin along with the waste stream. In the third stage the dichromate is reduced back to the trivalent cationic form which is subsequently removed from the waste stream by a second Amberlite ion-exchange bed in stage 4. Each step in this process is assessed in batch and flow mode using simulated and real tannery effluents.  相似文献   
77.
Bacon AM  Zhao HZ  Wang LJ  Thomas JE 《Applied optics》1995,34(24):5326-5330
We report a simple scheme for sensitive measurements of optical-noise spectra. Optical noise is separated from electronic noise when the output of an analog spectrum analyzer is real-time squared and then lock-in detected. This method directly yields the desired mean-square noise voltage, i.e., the power spectrum of the optical noise on a linear scale. To demonstrate this technique, the mean-square shot noise of a laser beam is measured and found to vary linearly with the laser power from several milliwatts down to one microwatt, in excellent quantitative agreement with predictions.  相似文献   
78.
Trisomy 21 develops as a result of nondisjunction of two homologous chromosomes during either the first or second meiotic division. One of the more important consequences of these genetic alterations is the predictable, although variable disturbance in the architecture of the craniofacial region [1]. Postnatal craniofacial morphology has been extensively studied in Down's syndrome (DS). However, little information is available on human prenatal development of the head and face in such patients. The time at which changes in craniofacial phenotype first emerge in Down's syndrome fetuses and at which physical growth begins to diverge from normal is unknown. To explore these questions, we compared prenatal craniofacial growth in 50 Down's syndrome fetuses with that of 555 fetuses judged to be "typical for body weight and age" using the method of log-linear allometry [2].  相似文献   
79.
Nanostructured diamond have potential applications in many biomedical related fields and demonstrated extraordinary capacity to influence cellular responses. Studying the surface property of nanodiamond and its influence to protein adsorption and subsequent cellular responses along with the mechanism behind such capacity becomes more important. Here the role of surface energy associated with nanostructured diamond in modulating fibronectin and osteoblast(OB, bone forming cells) responses was investigated. Nanocrystalline diamond(NCD) and submicron crystalline diamond(SMCD) films with controllable surface energy were prepared by microwave-enhanced plasma chemical vapor deposition(MPCVD) techniques. Fibronectin adsorption on the diamond films with varied surface energy values was measured via the enzyme-linked immunosorbent assay(ELISA) and the relationship between the surface energy and fibronectin adsorption was studied. The result indicated that fibronectin adsorption on nanostructured surfaces was closely related to both surface energy and material microstructures. The spreading and migration of OB aggregates(each containing 30–50 cells) on the NCD with varied surface energy values were also studied. The result indicates a correlation between the cell spreading and migration on nanodiamond and the surface energy of nanostructured surface.  相似文献   
80.
Choriocarcinoma arising in the placenta, or intraplacental choriocarcinoma, has seldom been reported, particularly in the absence of maternal metastases. Reluctance to diagnose choriocarcinoma in the presence of chorionic villi can delay diagnosis; however, timely diagnosis of choriocarcinoma is prognostically important, both for the mother and infant. We report the clinicopathologic findings in five mothers and infants in whom choriocarcinoma was identified in the placenta. None of the mothers had a history of gestational trophoblastic disease in previous pregnancies. Three placentas were similar with a single small lesion grossly suggesting a small infarct; microscopically these consisted of infarcted areas surrounded by choriocarcinoma. These three mothers were unusual in that none had metastatic choriocarcinoma; two were treated with chemotherapy and remained disease-free; the third was lost to follow-up shortly following delivery. The remaining two mothers had known pulmonary metastases at time of delivery. One of these latter two placentas contained a large marginal lesion microscopically identified as choriocarcinoma. The fifth placenta had rare microscopic foci of choriocarcinoma, and sheets of necrotic choriocarcinoma were identified in "blood clot" submitted with the placenta. In four of the five cases the choriocarcinoma appeared to be arising from otherwise normal chorionic villi, and in no case was there invasion of the villous stroma. All of the infants survived, and none had evidence of choriocarcinoma. These cases support the concept that choriocarcinoma associated with otherwise normal pregnancy arises in the placenta and may be more common than reported.  相似文献   
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