Achieving Diagnosis by Consensus

This paper provides an analysis of the collaborative work conducted at a multidisciplinary medical team meeting, where a patient’s definitive diagnosis is agreed, by consensus. The features that distinguish this process of diagnostic work by consensus are examined in depth. The current use of technology to support this collaborative activity is described, and experienced deficiencies are identified. Emphasis is placed on the visual and perceptual difficulty for individual specialities in making interpretations, and on how, through collaboration in discussion, definitive diagnosis is actually achieved. The challenge for providing adequate support for the multidisciplinary team at their meeting is outlined, given the multifaceted nature of the setting, i.e. patient management, educational, organizational and social functions, that need to be satisfied.

One-sided multiple comparisons for treatment means with a control mean

We study comparisons of several treatments with a common control when it is believed a priori that the treatment means, μ_i, are at least as large as the control mean, μ₀. In this setting, which is called a tree ordering, we study multiple comparisons that determine whether μ_i>μ₀ or μ_i=μ₀ for each treatment. The classical procedure by Dunnett (1955) and the step-down and step-up techniques by [Dunnett and Tamhane, 1991] and [Dunnett and Tamhane, 1992] are well known. The results in Marcus and Talpaz (1992) provide multiple comparisons based on the maximum likelihood estimates restricted by the tree ordering. We also study two-stage procedures that consist of the likelihood ratio test of homogeneity with the alternative constrained by the tree ordering followed by two-sample t comparisons with possibly different critical values for the two-sample comparisons. Marcus et al. (1976) discuss the use of closed tests in such situations and propose using a closed version of the restricted likelihood ratio test. We describe step-down versions of the Marcus-Talpaz, the two-stage, and the likelihood ratio procedures, as well as a closed version of the Marcus-Talpaz multiple comparison procedure. Using Monte Carlo techniques, we study the familywise errors and powers of these procedures and make some recommendations concerning techniques that perform well for all tree ordered mean vectors.     

Working memory capacity and the top-down control of visual search: Exploring the boundaries of "executive attention".

The executive attention theory of working memory capacity (WMC) proposes that measures of WMC broadly predict higher order cognitive abilities because they tap important and general attention capabilities (R. W. Engle & M. J. Kane, 2004). Previous research demonstrated WMC-related differences in attention tasks that required restraint of habitual responses or constraint of conscious focus. To further specify the executive attention construct, the present experiments sought boundary conditions of the WMC-attention relation. Three experiments correlated individual differences in WMC, as measured by complex span tasks, and executive control of visual search. In feature-absence search, conjunction search, and spatial configuration search, WMC was unrelated to search slopes, although they were large and reliably measured. Even in a search task designed to require the volitional movement of attention (J. M. Wolfe, G. A. Alvarez, & T. S. Horowitz, 2000), WMC was irrelevant to performance. Thus, WMC is not associated with all demanding or controlled attention processes, which poses problems for some general theories of WMC. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

The influence of target stoichiometry on early cell adhesion of co-sputtered calcium–phosphate surfaces

The nature of the initial interaction between calcium phosphate (Ca–P) thin films and osteoblasts can be influenced by a number of different properties including the phase, crystallinity, stoichiometry and composition of the surface. There is still a strong interest in developing and studying Ca–P surfaces that have the ability to accurately control the osteoblast response. Radio frequency (RF) magnetron sputtering is a technique that allows for accurate control of the properties of deposited Ca–P coatings and has been studied extensively because of this fact. In this work, Ca–P coatings were co-deposited using RF magnetron sputtering in order to study the effect of changing the target stoichiometry on the initial in vitro behavior of MG63 osteoblast-like cells. The samples produced were analysed both as-deposited and after thermal annealing to 500 °C. After annealing XPS analyses of the samples co-deposited using tricalcium phosphate (TCP) materials gave a Ca/P ratio of 1.71 ± 0.01, as compared to those co-deposited from hydroxyapatite (HA) materials, with a Ca/P of 1.82 ± 0.06. In addition to this, the curve fitted XPS data indicated the presence of low levels of carbonate in the coatings. Despite this the XRD results for all of the annealed coatings were shown to be characteristic of pure HA with a preferred 002 orientation. The atomic force microscopy results also highlighted that both types of coatings had surface features of a similar size (200–220 nm). Both surfaces exhibited a degree of surface degradation, even after 1 h of cell culture. However, the TCP derived surfaces showed an enhanced osteoblastic cell response in terms of cell adhesion and cell proliferation in the earlier stages of cell culture than the surfaces deposited from HA. An improvement in the initial cell attachment and a potential for increased cell proliferation rates is viewed as a highly advantageous result in relation to controlling the osteoblast response on these surfaces.     

预计算辐射传递技术

预计算辐射传递技术（Precomputed Radiance Transfer）简称PRT。它是由Sloan、P．-P．、Kautz J．、Snyder J．在SIGGRAPH 2002上发表的Precomputed Radiance Transfer for Real-Time Rendering in Dynamic，Low-Frequency Lighting Envirenments（在动态低频光照环境中用于实时渲染的预计算辐射传递技术）一文中提出的。由于其模拟全局光照的效果和效率均令人满意．因此这一技术已被越来越广泛地应用在下一代的游戏引擎中。     

Full‐color AMOLED with RGBW pixel pattern

Abstract— A full‐color AMOLED display with an RGBW color filter pattern has been fabricated. Displays with this format require about one‐half the power of analogous RGB displays. RGBW and RGB 2.16‐in.‐diagonal displays with average power consumptions of 180 and 340 mW, respectively, were characterized for a set of standard digital still camera images at a luminance of 100 cd/m². In both cases, a white‐emitting AMOLED was used as the light source, and standard LCD filters were used to provide the R, G, and B emission. The color gamuts of these displays were identical and the higher overall efficiency of the RGBW format results from two factors. First, a large fraction of a typical image is near neutral in color and can be reproduced using the white sub‐pixel. Second, the white sub‐pixel in an RGBW AMOLED display is highly efficient because of the absence of any color filter. The efficiency of these displays can be further enhanced by choosing a white emitter optimized to the target display white point (in this case D65). A two‐emission layer configuration based upon separate yellow and blue‐emitting regions is shown to be well suited for both the RGBW and RGB formats.     

Analysis of grocery chain pharmacists' work-related behaviors

OBJECTIVE: To measure grocery chain pharmacists' work-related behaviors to assess the impact of a Pharmaceutical Care Certificate Program (PCCP) and other future interventions intended to alter pharmacists' practice behaviors. DESIGN: This study used multidimensional work sampling (MWS), a work measurement methodology that breaks "work" into three components: activity (what was done), contact (with whom the activity was performed), and function (the purpose or objective of the activity). Pharmacists were signaled at random intervals during the workday by a random signal generator. A selection was made from a list of items in each of the three dimensions of work to form an activity-contact-function combination code that described the work-related behavior at that point in time. SETTING AND PARTICIPANTS: Pharmacists in 15 grocery chain stores in the Indianapolis area; 20 pharmacists were enrolled in Purdue University's PCCP and 10 served as controls. Data were collected for a period of six weeks during April through June 1997 before the beginning of the PCCP program. MAIN OUTCOME MEASURES: Pharmacists' work-related behaviors. RESULTS: Writing/keyboarding was the most frequently recorded activity (22%), followed by one-to-one meetings (21.6%), and drug preparation (18%). Pharmacists spent most of their time working alone (62.9%), while a smaller but still substantial proportion of time was spent interacting with patients (17.9%). The most frequently recorded purpose (i.e., function) of pharmacists' activities was drug distribution (23.9%), followed by personal time (12.4%), receiving or transferring a medication order (10.2%), and patient counseling (6.6%). Out of a possible, 1,760 activity-contact-function combinations, 10 accounted for 46.3% of all reported observations, with "Prepare drug-Self-Drug distribution" representing the most frequently recorded activity-contact-function combination (15.7%). CONCLUSION: MWS is useful in helping grocery chain management better understand how pharmacy personnel are currently being utilized. This study provides a baseline for evaluating the impact of training programs or other alterations in the practice environment on pharmacists' work-related behaviors.