Coronary artery dissection - a complication of cardiac catheterization without sequelae: case report and review of the literature

This report describes an acute right coronary artery dissection occurring during diagnostic cardiac catheterization. Following catheter manipulation in the vicinity of the aortic valve, the patient complained of mild chest discomfort and had transient electrocardiographic evidence of acute inferior wall myocardial infarction with runs of 2:1 atrioventricular block. Within 5 min, the EKG reverted to precatheterization appearance, and the patient was asymptomatic. Coronary angiography revealed a dissection of the proximal vessel without obstruction. The patient had no clinical sequelae while monitored in the intensive care unit. The patient underwent elective aortic and mitral valve replacement. The area of the dissection was directly visualized, and no abnormality was noted. We review the literature of spontaneous and iatrogenic coronary artery dissections with regard to pathology, diagnosis, and prognosis, and make recommendations for therapy.     

Bases of surgical treatment of bilateral suppurative processes in the lungs

In dogs subjected to gravitational overloadings (+Gx) according to a special training schedule the wall structure of the main arteries (carotid, humeral, femoral and aorta) was studied by histological methods. The amount of catecholamines (adrenaline and noradrenaline) in the venous blood plasma and in the adrenal tissue was the index of the sympathoadrenal system condition. It was demonstrated that in trained animals the tolerance threshold to continuously increasing overloadings (+Gx) rose. It was accompanied by an elevated amount of catecholamines in blood and the adrenals In the walls of the main arteries studied a moderate hyperelastosis and a slight collagenization of the adventitia was noted. All parts of the microcirculatory bed were moderately dilated, which favoured a better blood outflow. The data obtained demonstrate adaptational changes, which can be interpreted as indices of training and reliability of the organism.     

Responses of cells of posterior lateral line lobe to activation of electroreceptors in a mormyrid fish

Activity of neurons in the lateral line lobe was studied by intracellular recording of responses to stimulation of the lateral line nerves and of electroreceptors on the skin surface. Two modes of activation occur for cells responding to inputs from medium receptors. There is a direct monosynaptic input mediated by a single fiber. Short latency of response and antidromic spread from cell to afferent fiber indicate that the mediating synapse is electrotonic. The second input is from a number of additional fibers and is relayed, presumably by the granule cells. At shortest latency this input is disynaptic, probably involving at least one electrotonic synapse. A relay is indicated by heterosynaptic facilitation of the PSP and by pronounced depression with repetitive stimulation. The monosynaptic input may be on the axon. Disynaptic inputs are distributed over the dendrites, and impulses can arise in the dendrites. What appear to be spikes restricted to dendritic regions are often recorded as small brief potentials in the cell body. There is a somatotopic projection of the electroreceptors to the lateral line lobe. The monosynaptic input comes from a specific receptor in the periphery. Strong disynaptic inputs come from a group of receptors generally found anterior, but less commonly posterior or lateral, to the receptor giving rise to the monosynaptic input. Additional inputs that are inhibitory come from surrounding receptors. The inhibition only affects responses to the disynaptic input. The different inputs and multiple sites of impulse initiation must modify the cell's response as compared with the input-output relations that would be obtained with inputs acting on a single summation point. Cells responding to activation of large receptors are infrequent. They are characterized by low threshold, little latency change near threshold, and ability to follow high frequencies of stimulation.     

Reticular inhibition of evoked potentials of the ventro-basal thalamus and somatosensory cortex of the rat brain

In rats immobilized with d-tubocurarine conditioning electrical stimulation (100/s, 300 ms) of the central grey matter, reticular formation of the midbrain and medulla depressed focal potentials in thalamic ventro-basal complex and somatosensory cortex evoked by electrical stimulation of the forelimb or medial meniscus. The average threshold current for conditioning stimulation of these structures was 70, 100 and 120 muA. A comparison of intensity and duration of evoked potentials depression (for two-fold threshold stimulation of the brain stem) is failed to detect any difference between the stimulated structures: immediately after conditioning stimulation the amplitude of the cortical evoked potentials and post-synaptic components of the evoked potentials in the ventro-basal complex were 50-60% less than control amplitude (p less than 0.01) the depression persisting for 0.5-1 s. The presynaptic component of the thalamic evoked potentials was depressed only after three five-fold threshold conditioning stimulation. The brain stem stimulation did not cause any facilitatory effect on focal potentials evoked by maximal and submaximal stimulation of the forelimb or medial lemniscus.