Biochemical,functional, and histochemical effects of essential fatty acid deficiency in rat kidney

The present study was designed to examine the effects of EFA deficiency (EFAD) on biochemical, functional, and structural aspects of the kidney in growing and adult rats fed a normal or EFAD diet for 9 wk after weaning. Food and fluid intake (FI), urine volume, and Na⁺ and K⁺ excretions were measured weekly from weeks 4 to 8 by placing the rats in individual metabolic cages for 24 h. At week 9, Li⁺ and a 5% water load, respectively, were administered at 14 and 1.5 h prior to glomerular and proximal tubular function studies, as assessed by 3-h creatinine (C_Cr) and Li⁺ (C_Li+) clearances. Hematocrit and urine volume; serum and urine [Cr], [Li⁺], [Na⁺], and [K⁺]; and renal FA distribution were also measured. Data [corrected to 100 g/body weight (bw) and presented as means ±SEM] were significant, at P<-0.05. Despite a similar ingestion of solids from weeks 4 to 7 (weeks 7 to 10 of life), the rats on the EFAD diet showed a decreased body weight from week 5. From weeks 4 to 8, Fl and urine volume were similar for both groups, but the Fl increased at week 6 in the EFAD group; 24-h Na⁺ and K⁺ excretions were similar at all weeks, except for an increase in the EFAD group for both ions at week 7. In the EFAD group, C_Cr and C_Li+ decreased by 27 and 56.3%, respectively (385.7±33.4 vs. 280±21.1, and 21.0±2.1 vs. 9.2±1.1 μL/min/100 g; n=9 vs. 10), the latter result suggesting increased proximal reabsorption. The 3-h Na⁺ and K⁺ excretions were similar, but the Li⁺ decreased (0.78±0.06×10⁻² vs. 0.32±0.03×10⁻² μeq/min/100 g) in the EFAD group, giving additional support to the suggestion. Renal structure was normal and similar for both groups, but the EFAD group showed a more prominent proximal tubule brush border, together with heavier periodic acid-Schiff staining in all specimens from weeks 5 to 9. In the EFAD group, FA of the n−9 and n−7 series were higher, but most of the n−6 series were lower as a percentage of total lipids in the medulla and cortex. Medullary levels of 20∶4n−6 were maintained, 22∶4n−6 declined twice, arachidonic acid was maintained, and 20∶5n−3 was lower. The EFAD diet affected glomerular function, proximal tubular structure and function, and FA distribution in the rat kidney.     

<Emphasis Type="Italic">In situ</Emphasis> monitoring of solid fat content by means of pulsed nuclear magnetic resonance spectrometry and ultrasonics

An ultrasonic technique was developed to study the crystallization process of edible fats on-line. A chirp wave was used instead of the conventional pulser signal, thus achieving a higher signal-to-noise ratio. This enabled measurements to be made in concentrated systems [≈20% solid fat content (SFC)] through a 8.11-cm thick sample without significant signal loss. Fat samples were crystallized at 20, 25, and 30°C at a constant agitation rate of 400 rpm for 90 min. The crystallization process was followed by ultrasonic spectroscopy and a low-resolution pulsed nuclear magnetic resonance spectrometer. Specific relationships were found between ultrasonic parameters [integrated response, time of flight (TF), and full width half maximum] and SFC. TF, which is an indirect measurement of the ultrasonic velocity (v), was highly correlated to SFC (r ²>0.9) in a linear fashion (v=2.601 SFC+1433.0).     

Bi_4Ge_3O_(12):TR(TR=Pr,Eu,Ce)晶体的吸收和发光光谱

测量了Bi_4Ge_3O_(12)(BGO):Pr、Eu和Ce的吸收、激发和发光光谱。掺杂BGO吸收和激发带相应于pr~(3+)、Eu~(3+)和Ce~(3+)离子特征跃迁。Xe灯中不同波长激发所得到掺杂BGO的发光光谱可通过Bi~(3+)心和掺杂材料之间能量传输过程加以解释。Bi~(3+)心400—600mm发射强度因受到Ce杂质影响变弱,这现象在高Ce浓度晶体里更为显著。     

Effect of retempering with superplasticizer admixtures on slump loss and compressive strength of concrete subjected to prolonged mixing

To have concrete possesses the specified engineering properties, its slump loss has to be compensated somehow at construction site so that concrete could be placed and compacted properly. Several attempts have been tried so far to render concrete workable at construction site including starting with a high initial slump at the stationary plant, or retempering with water and/or with chemical admixtures at construction site. In this investigation, ASTM C 494 Type F superplasticizer was used for retempering concrete to restore its initial slump. Concrete mixes having an initial slump of about 19 cm were prepared and subjected to prolonged mixing with different mixing duration such as 30, 60, 90, 120, and 150 min following an initial mixing of 5 min to ensure homogeneity. At the end of each mixing period, cube specimens of 15 cm were cast from concrete retempered to its initial slump level and tested at the age of 28 days for compressive strength. Results revealed that compared to the concrete retempered with water, those retempered with a superplasticizer admixture have yielded significantly higher strength regardless of the mixing duration.     

Computational fluid dynamics (CFD) analysis and experimental study for toxic hazardous waste destruction in the cavity incinerator

We undertook numerical and experimental studies to develop a better incineration method for the destruction of CC1₄. A phenomenological model for the turbulent reaction of CC1₄, including a flame inhibition feature, has been successfully incorporated into a commercial code, simulating the incineration processes of this compound. The gaseous flow solution was obtained using SIMPLEST, a derivative of Patankar’s SIMPLE algorithm, with a k-ε turbulence model. A modified fast chemistry turbulent reaction model was developed to describe the flame inhibition due to the presence of CC1₄, considering the corresponding burning velocity data of these mixtures. An experiment was carried out on a 5.2 kW laboratory scale, transportable, cavity-type incinerator, which warrants a sufficient residence time and effective turbulent mixing by the formation of a strong recirculation region in a combustor. To this end, the specific configuration of the incinerator was manufactured to consist of two opposing jets and a rearward facing step. The calculated data were in close agreement with the experimental data for the concentrations of major species, such as CCI₄ and HCl, together with the temperature profiles. The experimental test gave the desired DRE of above 99.99%.     

制造泡沫玻璃的方法与模具

将泡沫玻璃配合料制备成块状物,将配合料块按规定间隙在模具中平铺码放并烧成,使配合料块熔为一体,形成较小变形的平板状泡沫玻璃.其制造模具是由底板、上盖及L型围板构成的箱型结构,模具各部位通过V字沟相互联结,保证各部位能自由地附着和脱离.模具多层码放烧制,模具间必须设置间隙.在模具上设置通孔可以有效地抑制膨胀过量问题.     

Decrease in serum levels of retinol and its binding protein (RBP) in infection

The main purpose of the present study was to determine the qualitative and quantiative effect of various infectious epsiodes on the blood serum levels of retinol and retinol-binding protein (RBP). Twenty-four children and 30 adult subjects were studied. The infections studied included chickenpox (n = 7); bronchitis (n = 9) upper respiratory infection (n = 30); tonsillitis (n = 2); diarrhea (n = 2) and one case each of: febrile stomatitis, nonspecific gastrointestinal alteration, urinary infection and shigellosis. In addition to retinol and RBP, the study determined changes in serum carotene, proteins, albumin and globulins. The results clearly demonstrate the marked depressing effect of infections on serum retinol, with a magnitude which in many cases reached more than 20 micrograms/dl, and in others more than 30 micrograms/dl. The RBP levels were significantly correlated with retinol, decreasing proportionally with infection. Serum albumin also decreased in most instances; and the globulin levels of the children, but not of the adults, were significantly higher during the infections. Carotene did not show important variations. The effects were more intense when fever accompanied the infectious episodes. These results are considered of great public health significance, in view of the large majorities, mainly children, who ordinarily subsist with very low serum retinol levels in the underdeveloped regions of the world. As infections attack these underpriviledged children, their serum retinol and RBP levels will likely drop a magnitude similar to that observed in the subjects of this study. They may then reach even more critically deficient retinol levels and be in serious danger of developing a severe acute state of clinical vitamin A deficiency.     

Obesity: Prevalence,Theories, Medical Consequences,Management, and Research Directions

Obesity and its associated disorders are a growing epidemic across the world. Many genetic, physiological, and behavioral factors play a role in the etiology of obesity. Diet and exercise are known to play a valuable role in the treatment and prevention of obesity and associated disorders such as hypertension, heart disease, and diabetes. Therefore, the purpose of this review is to examine the prevalence, etiology, consequences, and treatment of obesity.     

The onset of Taylor-Görtler vortices in impulsively decelerating swirl flow

The onset of hydrodynamical instability induced by impulsive spin-down to rest in a cylinder containing a Newtonian fluid is analyzed by using propagation theory. It is well-known that the primary transient swirl flow is laminar, but with initial high velocities secondary motion sets in at a certain time. The dimensionless critical time Τ_c to mark the onset of instability is presented here as a function of the Reynolds number Re. Available experimental data indicate that for large Re deviation of the velocity profiles from their momentum diffusion occurs starting from a certain time Τ≈4Τ_c. This means that secondary motion is detected at this characteristic time. It seems evident that during Τ_c⪯Τ⪯4Τ_c, secondary motion is relatively very weak and the primary diffusive momentum transfer is dominant.