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排序方式: 共有1416条查询结果,搜索用时 15 毫秒
41.
LA Knapp E Lehmann L Hennes ME Eberle DI Watkins 《Canadian Metallurgical Quarterly》1997,50(2):170-177
Skeletal development of transgenic mice with a type II collagen mutation was analyzed and compared with wild-type littermates. The single base substitution in Col2a1 resulted in a glycine to serine mutation within the helical domain and corresponded to one previously identified in a patient with the lethal human chondrodysplasia, hypochondrogenesis (Horton et al. [1992] Proc. Natl. Acad. Sci. U.S.A. 89:4583-4587). Skeletal staining of embryos from 14.5 through 18.5 days of gestation demonstrated a dwarf phenotype in the transgenic embryos, most notably short limb bones and vertebral column that was first detected at 15.5 days post-coitus. In addition to the reduced length, the extent of ossification was less in the transgenic mice. The architecture of the long bone growth plate was abnormal in the transgenic tissue, in particular there was no discernible proliferative zone. There were few stacks of characteristically flattened cells and the overall length of the growth plate in the mutant embryos was reduced. At the ultrastructural level, there were fewer collagen fibrils present in the transgenic mouse cartilage compared to that of wild-type littermates. Ultrastructural localization of collagen types II, IX and XI revealed a similar pattern between the transgenic and wild-type pups, suggesting that the collagen fibrils present in the matrix of littermates with both phenotypes had a similar composition. Skeletal analysis and cartilage histochemistry indicated that effect of the type II collagen mutation was to reduce the density of the collagen fibrils within the cartilage matrix which was associated with delayed bone formation and resulted in a short-limbed phenotype. 相似文献
42.
The authors investigated the effects of gender role conflict (GRC) on 148 18–55-yr-old college men's scores of psychological well-being, substance usage, and attitudes toward psychological help-seeking. Each of the 4 GRC variables was significantly related to at least 1 variable of interest. The Success, Power, and Competition variable of GRC was significantly related to (a) a decrease in psychological well-being, including scores for Trait Anger, the Angry Reaction subtype of trait anger, and the Angry Temperament subtype of trait anger, and (b) an increased report of alcohol usage. The Restricted Emotionality variable of GRC was significantly related to (a) a decrease in psychological well-being, including scores for Trait Anger and Trait Anxiety; (b) negative attitudes toward help-seeking; and (c) an increased similarity in personality style to chemical abusers. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
43.
Magrans-Courtney T Wilborn C Rasmussen C Ferreira M Greenwood L Campbell B Kerksick CM Nassar E Li R Iosia M Cooke M Dugan K Willoughby D Soliah L Kreider RB 《Journal of the International Society of Sports Nutrition》2011,8(1):8-17
Background
The purpose of this study was to determine whether sedentary obese women with knee OA initiating an exercise and weight loss program may experience more beneficial changes in body composition, functional capacity, and/or markers of health following a higher protein diet compared to a higher carbohydrate diet with or without GCM supplementation.Methods
Thirty sedentary women (54 ± 9 yrs, 163 ± 6 cm, 88.6 ± 13 kg, 46.1 ± 3% fat, 33.3 ± 5 kg/m2) with clinically diagnosed knee OA participated in a 14-week exercise and weight loss program. Participants followed an isoenergenic low fat higher carbohydrate (HC) or higher protein (HP) diet while participating in a supervised 30-minute circuit resistance-training program three times per week for 14-weeks. In a randomized and double blind manner, participants ingested supplements containing 1,500 mg/d of glucosamine (as d-glucosamine HCL), 1,200 mg/d of chondroitin sulfate (from chondroitin sulfate sodium), and 900 mg/d of methylsulfonylmethane or a placebo. At 0, 10, and 14-weeks, participants completed a battery of assessments. Data were analyzed by MANOVA with repeated measures.Results
Participants in both groups experienced significant reductions in body mass (-2.4 ± 3%), fat mass (-6.0 ± 6%), and body fat (-3.5 ± 4%) with no significant changes in fat free mass or resting energy expenditure. Perception of knee pain (-49 ± 39%) and knee stiffness (-42 ± 37%) was decreased while maximal strength (12%), muscular endurance (20%), balance indices (7% to 20%), lipid levels (-8% to -12%), homeostasis model assessment for estimating insulin resistance (-17%), leptin (-30%), and measures of physical functioning (59%), vitality (120%), and social function (66%) were improved in both groups with no differences among groups. Functional aerobic capacity was increased to a greater degree for those in the HP and GCM groups while there were some trends suggesting that supplementation affected perceptions of knee pain (p < 0.08).Conclusions
Circuit style resistance-training and weight loss improved functional capacity in women with knee OA. The type of diet and dietary supplementation of GCM provided marginal additive benefits.Trial Registration
ClinicalTrials.gov: NCT01271218 相似文献44.
Catalytic steam gasification of Miscanthus X giganteus in fluidised bed reactor on olivine based catalysts 总被引:1,自引:0,他引:1
Rudy MichelSergio Rapagnà Manuela Di Marcello Philippe BurgMuriel Matt Claire CoursonRené Gruber 《Fuel Processing Technology》2011,92(6):1169-1177
The Miscanthus X giganteus (MXG) presents many advantages (high yield, perennial crop, easy harvesting…) so it can be considered as a good candidate in terms of renewable energy sources. Several works have been carried out and were devoted to the MXG, especially in the agricultural field, but this study is the first which deals with gasification in order to produce syngas. The catalytic steam gasification of MXG in a fluidised bed reactor into presence of olivine based catalysts was investigated. Three parameters were studied, the temperature (800 °C and 900 °C), the pellets size (6 mm and 8 mm) and the nature of catalyst (olivine and Ni/olivine). Noteworthy is the efficiency shown by the Ni/olivine at 800 °C, which leads to the production of 1.7 m3 kg− 1 daf of gas, containing 50% of H2. Ni/olivine catalyst was characterised by XRD, TPR and SEM-EDX in order to monitor its structural changes during the process. Moreover, a solvent system of tar recovery was tested, which allows to obtain a more representative set of the whole tars. Then, the tars composition was determined by GC/MS. The identification of different compounds shows the presence of different PAHs, in majority naphthalene. 相似文献
45.
Zhuo Li Wei Lin Kyoung-Sik Moon Stewart J. Wilkins Yagang Yao Ken Watkins Liliane Morato Chingping Wong 《Carbon》2011,49(13):4138-4148
An anomalous decrease in the thermal stability of silicone was observed when carbon nanotubes (CNTs) were added as fillers. The decreased thermal stability is found to result from the residues of cobalt nanoparticles in CNTs, whereas CNTs synthesized with other metal catalysts do not show such a phenomenon. The analysis of thermal degradation products indicates that CNT fillers do not change the mechanism of the thermal degradation of silicone but cobalt nanoparticles within CNTs may accelerate the degradation through free radical generation. Radical scavengers such as hindered amines and impurity-free CNTs, or removal of cobalt nanoparticles by acid treatment, can mitigate the accelerated thermal degradation. 相似文献
46.
M. R. Ganjali P. Norouzi F. Faridbod S. Riahi M. R. Yaftian A. Zamani D. Matt 《Journal of Applied Electrochemistry》2007,37(7):827-833
A Th4+ ion-selective membrane sensor was fabricated from poly (vinyl chloride) (PVC) matrix membrane containing 2-(diphenylphosphorothioyl)-N′,N′-diphenyl acetamide (DPTD) as a neutral carrier, potassium tetrakis (p-chlorophenyl) borate (KTpClPB) as anionic excluder and o-nitrophenyloctyl ether (NPOE) as a plasticizing solvent mediator. The effects of the membrane composition, pH and additive
anionic influence on the response properties were investigated. The sensor, comprising 30% PVC, 63% solvent mediator, 4% ionophore
and 3% anionic additive demonstrates the best potentiometric response characteristics. It displays Nernstian behavior (15.2 ± 0.5 mV
per decade) over the concentration range 1.0 × 10−2–1.0 × 10−6 M. The detection limit of the electrode is 6.3 × 10−7 M (∼140 ng/ml). The response time of the electrode is 30 s .The sensor can be used in the pH range 3.0–9.0 for about 6 weeks.
The membrane sensor was used as an indicator electrode in the potentiometric titration of Th4+ ions with EDTA. It was successfully applied to the determination of thorium ions in binary mixture. 相似文献
47.
Terrance D. Loecke Cynthia A. Cambardella Matt Liebman 《Nutrient Cycling in Agroecosystems》2012,93(1):65-74
Understanding how the quality of organic soil amendments affects the synchrony of nitrogen (N) mineralization and plant N uptake is critical for optimal agronomic N management and environmental protection. Composting solid livestock manures prior to soil application has been promoted to increase N synchrony; however, few field tests of this concept have been documented. Two years of replicated field trials were conducted near Boone, Iowa to determine the effect of composted versus fresh solid swine manure (a mixture of crop residue and swine urine and feces produced in hoop structures) on Zea mays (maize) N uptake, in situ soil net N mineralization, and soil inorganic N dynamics. Soil applications of composted manure increased maize N accumulation by 25?% in 2000 and 21?% in 2001 compared with fresh manure applications (application rate of 340?kg?N?ha?1). Despite significant differences in net N mineralization between years, within year seasonal total in situ net N mineralization was similar for composted and fresh manure applications. Partial N budgets indicated that changes in soil N pools (net N mineralization and soil inorganic N) in the surface 20?cm accounted for 67?% of the total plant N accumulation in 2000 but only 16?% in 2001. Inter-annual variation in maize N accumulation could not be attributed to soil N availability. Overall, our results suggest that composting manures prior to soil application has no clear benefit for N synchrony in maize crops. Further work is required to determine the biotic and abiotic factors underlying this result. 相似文献
48.
Matt Wallace Ryan McBride Siam Aumi Prashant Mhaskar John House Tim Salsbury 《Chemical engineering science》2012,69(1):45-58
Many systems used in buildings for heating, ventilating, and air-conditioning waste energy because of the way they are operated or controlled. This paper explores the application of model predictive control (MPC) to air-conditioning units and demonstrates that the closed-loop performance and energy efficiency can be improved over conventional approaches. This work focuses on the problem of controlling the vapor compression cycle (VCC) in an air-conditioning system, containing refrigerant which is used to provide cooling. The VCC considered in this work has two manipulated variables that affect operation: compressor speed and the position of an electronic expansion valve. The system is subject to constraints, such as the range of permissible superheat, and also needs to regulate temperature variables to set points. An MPC strategy is developed for this type of system based on linear models identified from data obtained from a first-principles model of the VCC. The MPC strategy incorporates economic measures in the objective function as well as control objectives. Tests are carried out on a simulated VCC system that is linked to a simulation of a realistic building that is developed in the U.S. Department of Energy Computer Simulation Program, EnergyPlus. The MPC demonstrated significantly better tracking control relative to conventional approaches (a reduction of 70% in terms of the integral of squared error for step changes in the temperature set-point), while reducing the VCC energy requirements by 16%. The paper describes the control approach in detail and presents results from the tests. 相似文献
49.
50.
Allen?J?TaylorEmail author Henry?Wong Karen?Wish Jon?Carrow Debulon?Bell Jody?Bindeman Tammy?Watkins Trudy?Lehmann Saroj?Bhattarai Patrick?G?O'Malley 《Nutrition journal》2003,2(1):4