Exploration on efficient similar sentences extraction

Measuring the semantic similarity between sentences is an essential issue for many applications, such as text summarization, Web page retrieval, question-answer model, image extraction, and so forth. A few studies have explored on this issue by several techniques, e.g., knowledge-based strategies, corpus-based strategies, hybrid strategies, etc. Most of these studies focus on how to improve the effectiveness of the problem. In this paper, we address the efficiency issue, i.e., for a given sentence collection, how to efficiently discover the top-k semantic similar sentences to a query. The previous methods cannot handle the big data efficiently, i.e., applying such strategies directly is time consuming because every candidate sentence needs to be tested. In this paper, we propose efficient strategies to tackle such problem based on a general framework. The basic idea is that for each similarity, we build a corresponding index in the preprocessing. Traversing these indices in the querying process can avoid to test many candidates, so as to improve the efficiency. Moreover, an optimal aggregation algorithm is introduced to assemble these similarities. Our framework is general enough that many similarity metrics can be incorporated, as will be discussed in the paper. We conduct extensive experimental evaluation on three real datasets to evaluate the efficiency of our proposal. In addition, we illustrate the trade-off between the effectiveness and efficiency. The experimental results demonstrate that the performance of our proposal outperforms the state-of-the-art techniques on efficiency while keeping the same high precision as them.     

Experimental investigation of structure vulnerabilities to firebrand showers

Attempting to experimentally quantify the vulnerabilities of structures to ignition from firebrand showers has remained elusive. The coupling of two facilities has begun to unravel this difficult problem. The NIST Firebrand Generator (NIST Dragon) is an experimental device that can generate a firebrand shower in a safe and repeatable fashion. Since wind plays a critical role in the spread of WUI fires in the USA and urban fires in Japan, NIST has established collaboration with the Building Research Institute (BRI) in Japan. BRI maintains one of the only full scale wind tunnel facilities in the world designed specifically for fire experimentation; the Fire Research Wind Tunnel Facility (FRWTF). The present investigation is aimed at extensively quantifying firebrand penetration through building vents using full scale tests. A structure was placed inside the FRWTF and firebrand showers were directed at the structure using the NIST Dragon. The structure was fitted with a generic building vent, consisting of only a frame fitted with a metal mesh. Six different mesh sizes openings were used for testing. Behind the mesh, four different materials were placed to ascertain whether the firebrands that were able to penetrate the building mesh assembly could ignite these materials. Reduced scale test methods afford the capability to test new vent technologies and may serve as the basis for new standard testing methodologies. As a result, a new experimental facility developed at NIST is presented and is known as the NIST Dragon's LAIR (Lofting and Ignition Research). The NIST Dragon's LAIR has been developed to simulate a wind driven firebrand attack at reduced scale. The facility consists of a reduced scale Firebrand Generator (Baby Dragon) coupled to a bench scale wind tunnel. Finally, a series of full scale experiments were conducted to visualize the flow of firebrands around obstacles placed downstream of the NIST Dragon. Firebrands were observed to accumulate in front of these obstacles at a stagnation plane, as was observed when the structure was used for firebrand penetration through building vent experiments, due to flow recirculation. The accumulation of firebrands at a stagnation plane presents a severe threat to ignitable materials placed near structures.     

Production of Gentiobiose from Hydrothermally Treated Aureobasidium pullulans β-1,3-1,6-Glucan

We report production of the functional disaccharide gentiobiose β-D-Glcp-(1→6)-D-Glc by a hydrolysis reaction of hydrothermally treated Aureobasidium pullulans β-1,3-1,6-glucan as the substrate and Kitalase as the enzyme. Gentiobiose was produced over the pH range 4−6 and the concentration of gentiobiose produced decreased above pH 7. The maximum value of gentiobiose production was unaffected by the enzyme concentration. The maximum concentration of gentiobiose produced was dependent on the substrate concentration whereas the maximum ratio of gentiobiose to glucose was not. The production of gentiobiose from yeast β-1,3-1,6-glucan was lower than that from A. pullulans β-1,3-1,6-glucan.     

Mechanism of Magnetite Seam Formation and its Role for FeO Scale Transformation

The phase transformation behavior of a thermally grown oxide scale of FeO on pure-Fe and an Fe–2wt%Au alloy was investigated. Particular attention was paid to formation of a magnetite seam, which is the Fe₃O₄ layer formed at the FeO/alloy interface at an initial stage of the phase transformation, since it has important effects on the overall phase transformation of FeO scale. A thin Au(Fe) layer was found to develop on the Fe–Au alloy at the FeO/alloy interface after 32 min of oxidation at 750 °C in air. This Au(Fe) layer prevented formation of a magnetite seam and accelerated the FeO eutectoid reaction. The Au(Fe) layer acted as a “chemical diffusion barrier” for inward diffusion of Fe from the FeO to the alloy substrate across the FeO/alloy interface and prevented magnetite seam formation.     

Molecular Depolymerization of Moist Sweet Potato Starch Melt by Shearing Force under an Elevated Temperature

Sweet potato starch (SPS) with 20 or 25% moisture was heated and then fused at 150°C for 15 min under pressurization at 30–500 Kg/cm². At the same time, the heated SPS melt was extruded through a capillary tube under specified pressure in order to give shearing force. Thus, intact SPS, heated SPS and heated sheared SPS specimen were prepared and examined. The heated and heated sheared SPS did not contain any pyrolysis products because their spectrum profiles were the same as that of intact SPS. By heating and shearing, the intact SPS molecule was depolymerized into small molecules including a few amount of glucose. This finding was revealed by means of molecular weight estimation by viscometry and by gel filtration. The shearing toward SPS melt markedly stimulated the depolymerization while the effect of only heating on depolymerization of SPS was modulate in comparison with heated shearing. Water solubilities of intact SPS, heated SPS and heated sheared SPS with 20% moisture were 0.07, 3.5 and 51.5% respectively, and also the degrees of gelatinization of 1.8% for intact starch increased markedly to 29% for heated SPS and 80–95% (depending on the pressure at extrusion) for heated sheared SPS.     

Therapeutic Targets and Emerging Treatments in Advanced Chondrosarcoma

Simple SummaryChondrosarcomas develop chemoresistance to standard anticancer drugs, making it difficult to control unresectable or metastatic chondrosarcomas. To improve the clinical outcomes of chondrosarcoma, new treatment approaches, such as molecule-targeting agents and immunotherapy, are needed. Recent research has revealed promising biomarkers and therapeutic targets for chondrosarcoma. In addition, several molecule-targeting agents have shown favorable antitumor activities in several clinical studies in patients with advanced sarcomas, including chondrosarcoma. This review summarizes recent basic studies on biomarkers and therapeutic targets and recent clinical studies on treating chondrosarcomas.AbstractDue to resistance to standard anticancer agents, it is difficult to control the disease progression in patients with metastatic or unresectable chondrosarcoma. Novel therapeutic approaches, such as molecule-targeting drugs and immunotherapy, are required to improve clinical outcomes in patients with advanced chondrosarcoma. Recent studies have suggested several promising biomarkers and therapeutic targets for chondrosarcoma, including IDH1/2 and COL2A1. Several molecule-targeting agents and immunotherapies have shown favorable antitumor activity in clinical studies in patients with advanced chondrosarcomas. This review summarizes recent basic studies on biomarkers and molecular targets and recent clinical studies on the treatment of chondrosarcomas.     

Liquid‐phase sintering of highly Na+ ion conducting Na3Zr2Si2PO12 ceramics using Na3BO3 additive

Na₃Zr₂Si₂PO₁₂ (NASICON) is a promising material as a solid electrolyte for all‐solid‐state sodium batteries. Nevertheless, one challenge for the application of NASICON in batteries is their high sintering temperature above 1200°C, which can lead to volatilization of light elements and undesirable side reactions with electrode materials at such high temperatures. In this study, liquid‐phase sintering of NASICON with a Na₃BO₃ (NBO) additive was performed for the first time to lower the NASICON sintering temperature. A dense NASICON‐based ceramic was successfully obtained by sintering at 900°C with 4.8 wt% NBO. This liquid‐phase sintered NASICON ceramic exhibited high total conductivity of ~1 × 10^?3 S cm^?1 at room temperature and low conduction activation energy of 28 kJ mol^?1. Since the room‐temperature conductivity is identical to that of conventional high‐temperature‐sintered NASICON, NBO was demonstrated as a good liquid‐phase sintering additive for NASICON solid electrolyte. In the NASICON with 4.8 wt% NBO ceramic, most of the NASICON grains directly bonded with each other and some submicron sodium borates segregated in particulate form without full penetration to NASICON grain boundaries. This characteristic composite microstructure contributed to the high conductivity of the liquid‐phase sintered NASICON.     

Chemical‐Free Approach for Z‐Isomerization of Lycopene in Tomato Powder: Hot Air and Superheated Steam Heating above the Melting Point of Lycopene

Z‐isomers of lycopene exhibit higher bioavailability and antioxidant capacity than those of the all‐E‐isomer. Therefore, it is important to develop an efficient and environmentally friendly procedure for Z‐isomerization. The current methods for Z‐isomerization of (all‐E)‐lycopene use toxic chemicals such as organic solvents and catalysts. This study is aimed to develop a chemical‐free method for Z‐isomerization of (all‐E)‐lycopene in tomato powder by hot air and superheated steam heating. The Z‐isomerization reaction is promoted by heating above the melting point of lycopene. When heated with superheated steam, the thermal decomposition of lycopene is suppressed compared to that when heated with hot air. When tomato powder is heated at 240 °C for 5 min by superheated steam, the total Z‐isomer content and remaining lycopene are 69.0% and 90.7%, respectively, while with hot air heating, the total Z‐isomer content and remaining lycopene are 69.9% and 68.0%, respectively. These results indicate that the thermal Z‐isomerization of lycopene occurs in the molten state and heating in a low oxygen atmosphere suppresses the thermal decomposition of lycopene. Practical Applications: Tomato powder rich in lycopene Z‐isomers is an important ingredient for the food and animal feed industries. Since Z‐isomers of lycopene are more soluble in solvents including ethanol which is a low‐toxicity and environmentally friendly solvent, the efficiency of lycopene extraction with ethanol can be improved by using the Z‐isomer‐rich tomato powder as a raw material. The obtained Z‐isomer‐rich extract has a high added value because the Z‐isomers have higher bioavailability and antioxidant capacity than those of the all‐E‐isomer. In addition, since lycopene Z‐isomers exhibit higher accumulation efficiency and better color improvement in hen egg yolks than those of the all‐E‐isomer, Z‐isomer‐rich tomato powder is an effective animal feed.     

Effects of calcining conditions of kaolinite on pore structures of mesoporous materials prepared by the selective leaching of calcined kaolinite

This paper describes the effects of calcining conditions of kaolinite on pore structures of the porous materials obtained from the selective leaching of calcined kaolinite using KOH solution. Mesoporous -Al₂O₃ was the predominant crystalline phase in the samples calcined in the temperature range between 950°C and 1050°C for 24 h. The mean specific surface area of these samples was approximately 250 m² · g^–1 and the mean total pore volume was approximately 0.8 ml · g^–1. The pore size distribution curves of these samples showed a sharp peak at around 2–3 nm pore radius. This peak was sharper for the sample calcined at 1000°C for 24 h. On the other hand, the pore sizes of the sample calcined at 1100°C for 24 h increased abruptly to 10–20 nm and this change corresponded to the formation of mullite in the sample. The pore sizes of the samples calcined at 1100°C varied with calcining time. The specific surface area and total pore volume decreased, the longer the calcining time of the samples, and this was correlated with an increase in the amount of mullite in the samples.     

Hydrogen concentration on mirror surfaces of neutron bottles

Concentrations and depth distributions of the surface hydrogen and the surface deuterium in vacuum evaporated nickel layers and beryllium plates have been investigated by the ERDA method. It is shown that if the evaporation vacuum pressure is kept better than 10⁻⁶ Torr, the hydrogen adsorption from the residual gas during the evaporation is negligible and the hydrogen from residual or atmospheric gases after the evaporation is the main source of the surface hydrogen. Commercial beryllium plates are found to have surface hydrogen of about 10¹⁶ atoms cm². Deuterium treated samples, either in D₂ gas or heavy water, do not show more than possibly a partial replacement of hydrogen. The influence of substrates is small if the thickness of the evaporated nickel layer is more than 2000 Å. The measurements are in good agreement with previously published results.