A memetic algorithm for minimizing the total weighted completion time on a single machine under step-deterioration

In this paper, we consider minimizing total weighted completion time criteria on a single machine. Jobs processing times are step function of its starting time and all jobs have a common due date. First, we present some new lemmas and dominance properties for this NP-hard problem, and then a memetic algorithm using these properties is developed. We compare the solutions of the memetic algorithm with optimal solutions obtained from complete enumeration. The results show that the average percentage error of the proposed algorithm from optimal solutions is about 2% and as the variance of processing time increase, the percentage errors decrease.     

Building extraction from high-resolution satellite images in urban areas: recent methods and strategies against significant challenges

Building extraction from high-resolution satellite images (HRSI) in urban areas is an intricate problem. Recent studies proposed different methods during 2005–2015. However, in HRSI, they have not investigated the effects of challenges altogether. This paper studies the effects of non-building features which are the main drawbacks in building extraction. To overcome each challenge, it reviews recent strategies between 2005 and 2015. The pros and cons of each strategy are discussed, and proper strategies are combined to generate hybrid methods. Lower cost and fewer strategies are efficient attributes to recognize the best hybrid methods. Hybrid methods can be useful for different case studies in the future.     

Structural Properties of Networked Control Systems With Bandwidth Limitations and Delays

The structural properties of networked control systems with both bandwidth limitations and delays are investigated. Sufficient conditions are given for controllability (stabilizability) and reconstructibility (detectability). Our results enhance previous works by capturing bandwidth limitations and delays simultaneously. The adopted modeling framework could be readily used in control and estimation methods, including optimal and predictive schemes. It also facilitates the use of scheduling optimization algorithms in conjunction with the control scheme presented.     

A theory of mode of action of azolylalkylquinolines as DNA binding agents using automated flexible ligand docking

Azolylalkylquinolines (AAQs) are a family of quinolines with varying degrees of cytotoxic activity (comparable or moderately superior to adriamycin in some cases) developed in the past decade in our group where their exact mode of action is still unclear. In this study the most probable DNA binding mode of AAQs was investigated employing a novel flexible ligand docking approach by using AutoDock 3.0. Forty-nine AAQs with known experimental inhibitory activity were docked onto d(CGCAAATTTGCG)(2), d(CGATCG)(2) and d(CGCG)(2) oligonucleotides retrieved from the Protein Data Bank (PDB IDs: 102D, 1D12 and 1D32, respectively) as the representatives of the three plausible models of interactions between chemotherapeutic agents and DNA (groove binding, groove binding plus intercalation and bisintercalation, respectively). Good correlation (r(2)=0.64) between calculated binding energies and experimental inhibitory activities was obtained using groove binding plus intercalation model for phenyl-azolylalkylquinoline (PAAQ) series. Our findings show that the most probable mode of action of PAAQs as DNA binding agents is via intercalation of quinolinic moiety between CG base pairs with linker chain and azole moiety binding to the minor groove.     

An Immune-based Genetic Algorithm with Reduced Search Space Coding for Multiprocessor Task Scheduling Problem

Multiprocessor task scheduling is an important problem in parallel applications and distributed systems. In this way, solving the multiprocessor task scheduling problem (MTSP) by heuristic, meta-heuristic, and hybrid algorithms have been proposed in literature. Although the problem has been addressed by many researchers, challenges to improve the convergence speed and the reliability of methods for solving the problem are still continued especially in the case that the communication cost is added to the problem frame work. In this paper, an Immune-based Genetic algorithm (IGA), a meta-heuristic approach, with a new coding scheme is proposed to solve MTSP. It is shown that the proposed coding reduces the search space of MTSP in many practical problems, which effectively influences the convergence speed of the optimization process. In addition to the reduced search space offered by the proposed coding that eventuate in exploring better solutions at a shorter time frame, it guarantees the validity of solutions by using any crossover and mutation operators. Furthermore, to overcome the regeneration phenomena in the proposed GA (generating similar chromosomes) which leads to premature convergence, an affinity based approach inspired from Artificial Immune system is employed which results in better exploration in the searching process. Experimental results showed that the proposed IGA surpasses related works in terms of found makespan (20% improvement in average) while it needs less iterations to find the solutions (90% improvement in average) when it is applied to standard test benches.     

Reduction of Noise from Disc Brake Systems Using Composite Friction Materials Containing Thermoplastic Elastomers (TPEs)

Attempts have been made for the first time to prepare a friction material with the characteristic of thermal sensitive modulus, by the inclusion of thermoplastic elastomers (TPE) as viscoelastic polymeric materials into the formulation in order to the increase the damping behavior of the cured friction material. Styrene–butadiene–styrene (SBS), styrene–ethylene–butylene–styrene (SEBS) and nitrile rubber/polyvinyl chloride (NBR/PVC) blend system were used as TPE materials. In order to evaluate the viscoelastic parameters such as loss factor (tan δ) and storage modulus (E′) for the friction material, dynamic mechanical analyzer (DMA) were used. Natural frequencies and mode shapes of friction material and brake disc were determined by modal analysis. However, NBR/PVC and SEBS were found to be much more effective in damping behavior. The results from this comparative study suggest that the damping characteristics of commercial friction materials can be strongly affected by the TPE ingredients. This investigation also confirmed that the specimens with high TPE content had low noise propensity.     

Truck Loading and Fatigue Damage Analysis for Girder Bridges Based on Weigh-in-Motion Data

Based on data collected by weigh-in-motion (WIM) measurements, truck traffic is synthesized by type and loading condition. Three-dimensional nonlinear models for the trucks with significant counts are developed from the measured data. Six simply supported multigirder steel bridges with spans ranging from 10.67 m (35 ft) to 42.67 m (140 ft) are analyzed using the proposed method. Road surface roughness is generated as transversely correlated random processes using the autoregressive and moving average model. The dynamic impact factor is taken as the average of 20 simulations of good road roughness. Live-load spectra are obtained by combining static responses with the calculated impact factors. A case study of the normal traffic from a specific site on the interstate highway I-75 is illustrated. Static loading of the heaviest in each truck type is compared with that of the American Association of State Highway and Transportation Officials standard design truck HS20-44. Several important trucks causing fatigue damage are found.     

Association between antiinflammatory cytokine,IL‐10, and sleep quality in patients on maintenance hemodialysis

Elevated proinflammatory cytokines have been attributed to poor sleep quality in patients receiving hemodialysis. This is the first investigation about the relationship between sleep quality and circulating levels of antiinflammatory markers in these patients. A total of 72 patients who were receiving maintenance hemodialysis were enrolled in this cross‐sectional study. The Pittsburgh Sleep Quality Index (PSQI) was used to measure sleep quality. Patients were divided into two groups: good sleepers (PSQI score < 5) and poor sleepers (PSQI score ≥ 5). Assessments were made for serum biochemical parameters (albumin, parathyroid hormone), inflammatory (interleukin [IL]‐6, tumor necrosis factor‐alpha [TNF‐α], and high‐sensitivity c‐reactive protein [hs‐CRP] ) and antiinflammatory (IL‐10) markers. Fifty‐four patients (75%) were classified as poor sleepers. Poor sleepers showed significantly lower levels of serum IL‐10 and higher serum triglyceride and parathyroid hormone concentrations. These patients were more likely to have more comorbidities. The global PSQI score was significantly correlated with serum IL‐10 (p = 0.03) and triglyceride levels (p = 0.01). Multivariate logistic regression analysis showed a direct correlation between PSQI and having comorbidities (p = 0.011, odds ratio [OR] = 3.918; confidence interval 95% [CI] = 2.742–19.031), between PSQI and serum triglyceride (p = 0.027, OR = 1.027 [95% CI = 1.007–1.048] ), and an inverse correlation between PSQI and serum IL‐10 level (p = 0.021, OR = 0.424 [95% CI = 0.195–0.922]). Reduced circulating levels of the antiinflammatory cytokine IL‐10 were significantly associated with poor sleep quality in hemodialysis patients. Factors including serum IL‐10 and triglyceride concentrations and having comorbidities may predict patients prone to poor sleep quality.     

A planar micro-concentrator/injector for low power consumption microchromatographic analysis of benzene and 1,3 butadiene

In the present study, we present the first steps of the development of a low power consumption GC microsystem for the analysis of benzene in the presence of butadiene, involved in petrochemical industrial applications. This system is made by coupling a low power consumption planar microhotplate based on a preconcentrator with good preconcentration capability and a spiral microchromatographic column that presents a separation capability of both compounds at room temperature, when tested in front of a gas sensor. The first characterization results of the device showed a successful injection of benzene and butadiene when placed in front of the micro-separation module.     

通过双级固溶热处理制备新型高强Al−10.5Si−3.4Cu−0.2Mg合金

通过析出硬化提高Al?Si?Cu合金的力学性能.这些合金对时效硬化的反应非常缓慢.为了解决这一问题,在Al?10.5Si?3.4Cu合金中分别加入0.2％、0.4％和0.7％(质量分数)的镁.该新型合金在固溶处理阶段经过两种不同的析出硬化过程.结果表明,添加不同含量的镁可加速该合金对时效处理的响应,提高其硬度和强度.双...