The relationship of the restriction fragment length polymorphism of the apo-B gene to the blood lipid spectrum in patients with ischemic heart disease

Restriction fragment length polymorphism of the apo-B gene at the Xbal restriction site was detected. The association between RFLP of the apo-B gene and the level of lipid metabolism indices was revealed. The levels of total cholesterol LDLP CH and atherogenicity coefficient were significantly higher in homozygotes with this restriction site (X2X2) than in homozygotes X1X1 and heterozygotes.     

A clinico-laboratory validation of the combined therapy of lichen ruber planus of the oral mucosa

Fifty-two patients with lichen planus were examined over the course of disease using clinical, microbiological, and histological methods. Treatment protocols aimed at normalization of microbiocenosis have been developed, based on the detected microbiological and histological changes.     

猴头菌子实体与液态发酵菌丝体活性成分差异及其在改善胃部疾病中的应用进展

猴头菌是传统的食药两用菌,具有猴头菌多糖、猴头菌素、猴头菌酮、麦角甾醇等多种活性成分,对胃炎、胃溃疡、胃癌等胃部疾病具有有益调节作用。猴头菌有子实体和菌丝体两种形态,菌丝体又分为固态发酵菌丝体与液态发酵菌丝体。本文主要对比阐述了猴头菌子实体与液态发酵菌丝体活性成分差异以及它们在改善胃部疾病中相关研究成果,以期为猴头菌液态发酵菌丝体规模化、工业化、自动化生产,以及功能食品和食用菌基天然药物的开发提供依据和参考。     

并行密文倒排索引研究

加密数据是保护用户隐私的一个方法,特别在开放系统中的数据处理需求更为迫切,但要解决如何在密文上进行检索的问题。针对SSE-1密文检索方案的一些性能缺陷,采用不同的加密策略,在lucene倒排索引的基础上,设计了密文倒排索引Crypt-Lucene,同时结合云计算特点,设计了并行构建Crypt-Lucene方案,理论分析了方案的性能,并通过实验证明了方法的有效性。实验结果表明,Crypt-Lucene与SSE-1相比,索引构建时间减少了约为60%,同时具有较好的空间性能,对于大文档集合,利用MapReduce在4结点构成的Hadoop集群上并行构建8个Crypt-Lucene索引能减少83.4%的时间。     

基于层次化可塑性回声状态网络的混沌时间序列预测

为了提高回声状态网络对于混沌时间序列特征提取与预测的能力,提出一种层次化可塑性回声状态网络模型.该模型将多个储备池顺序连接,通过逐层特征变换的方式增强对非线性多尺度动态特征的提取能力.同时,引入神经科学中的内在可塑性机制模拟真实生物神经元的放电率分布,以最大化神经元的信息传递为目标对储备池进行预训练.层次化可塑性回声状态网络不仅能够增加模型的容量,降低随机投影所带来的不稳定性,而且也为理解储备池的表示、处理、记忆及储存操作提供一种新的思路.仿真实验结果表明,相比于其他7种改进的回声状态网络模型,所提出的模型在人造数据和真实数据所构成的混沌时间序列预测任务中均能取得最优的预测精度.     

Chromosomal aberrations, sister-chromatid exchanges, cells with high frequency of SCE, micronuclei and comet assay parameters in 1, 3-butadiene-exposed workers

The association of occupational exposure to 1,3-butadiene (BD) and induction of cytogenetic damage in peripheral lymphocytes was studied in 19 male workers from a monomer production unit and 19 control subjects from a heat production unit. The exposure to BD was measured by passive personal monitors. The following biomarkers were used: chromosomal aberrations (CA), sister chromatid exchanges (SCE), cells with a high frequency of SCE (HFC), micronuclei, comet assay parameters like tail length (TL) and percentage of DNA in tail [T (%)] and polymorphisms of GSTM1 and GSTT1 genotypes. BD exposure with a median value of 0.53 mg/m3 (range: 0.024-23.0) significantly increased (a) the percentage of cells with chromosomal aberrations in exposed vs. control groups (3.11% vs. 2.03%, P<0.01), (b) the frequency of SCE per cell (6.96 vs. 4.87, P<0.001), and (c) the percentage of HFC (19.9% vs. 4.1%, P<0.001). BD exposure had no significant effects on formation of micronuclei and on comet assay parameters. Effect of smoking was observed only for HFC in BD-exposed group. GSTM1 genotype affected chromosomal aberrations in exposed group, while GSTT1 genotype affected chromosomal aberrations in controls. No effect of GSTM1 or GSTT1 genotypes was observed on any other biomarkers used.     

浅谈太阳能光伏建筑一体化

论述了太阳能光伏建筑一体化的定义、原理、类型、方式、特点和要求;光伏建筑一体化太阳能将成为功效最佳、价格最低廉的替代新能源。太阳能光伏建筑一体化发展任重道远。     

基于FET结构的Pt-LaF_3混合膜溶解氧传感器

研制了一种基于 FET结构的 Pt- L a F3混合膜全固态溶解氧传感器 .对 Pt- L a F3敏感膜的敏感机制以及传感器的器件结构和响应特性进行了分析 ,并实际测试了器件特性 ,给出了在不同工作点和不同温度条件下器件的输出电压对溶解氧浓度变化的响应曲线     

The effect of post-injury spinal position on canal occlusion in a cervical spine burst fracture model

STUDY DESIGN: The canal space of burst-fractured, human cervical spine specimens was monitored to determine the extent to which spinal position affected post-injury occlusion. OBJECTIVE: To test the null hypothesis that there is no difference in spinal canal occlusion as a function of spinal positioning for a burst-fractured cervical spine model. SUMMARY OF BACKGROUND DATA: Although previous studies have documented the effect of spinal positioning on canal geometry in intact cadaver spines, to the authors' knowledge, none has examined this relationship specifically in a burst fracture model. METHODS: Eight human cervical spine specimens (levels C1 to T3) were fractured by axial impact, and the resulting burst injuries were documented using post-injury radiographs and computed tomography scans. Canal occlusion was measured using a custom transducer in which water was circulated through a section of flexible tygon tubing that was passed through the spinal canal. Any impingement on the tubing produced a rise in fluid pressure that was monitored with a pressure transducer. Each spine was positioned in flexion, extension, lateral (and off-axis) bending, axial rotation, traction, and compression, while canal occlusion and angular position were monitored. Occlusion values for each position were compared with measurements taken with the spine in neutral position. RESULTS: Compared with neutral position, compression, extension, and extension combined with lateral bending significantly increased canal occlusion, whereas flexion decreased the extent of occlusion. In extension, the observed mechanism of occlusion was ligamentum flavum bulge caused by ligament laxity resulting from reduced vertebral body height. CONCLUSIONS: Increased compression of the spinal cord after injury may lead to more extensive neurologic loss. This study demonstrated that placing a burst-fractured cervical spine into either extension or compression significantly increased canal occlusion as compared with occlusion in a neutral position.