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101.
102.
Khayati Yashar Kang Jee Eun Karwan Mark Murray Chase 《Networks and Spatial Economics》2021,21(3):609-637
Networks and Spatial Economics - The pace of changes in automating cars has sped up in the last few decades. Autonomous Vehicles (AVs) will dramatically change the future of transportation, and... 相似文献
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Pevindu Abeysinghe Natalie Turner Isabella Morean Garcia Eman Mosaad Hassendrini N. Peiris Murray D. Mitchell 《International journal of molecular sciences》2020,21(23)
Abnormal uterine function affects conception rate and embryo development, thereby leading to poor fertility and reproduction failure. Exosomes are a nanosized subclass of extracellular vesicles (EV) that have important functions as intercellular communicators. They contain and carry transferable bioactive substances including micro RNA (miRNA) for target cells. Elements of the cargo can provide epigenetic modifications of the recipient cells and may have crucial roles in mechanisms of reproduction. The dairy industry accounts for a substantial portion of the economy of many agricultural countries. Exosomes can enhance the expression of inflammatory mediators in the endometrium, which contribute to various inflammatory diseases in transition dairy cows. This results in reduced fertility which leads to reduced milk production and increased cow maintenance costs. Thus, gaining a clear knowledge of exosomal epigenetic modifiers is critical to improving the breeding success and profitability of dairy farms. This review provides a brief overview of how exosomal miRNA contributes to inflammatory diseases and hence to poor fertility, particularly in dairy cows. 相似文献
105.
The microstructure and elastic shear modulus of cold-set gels formed from high-sugar aqueous mixtures of gelatin (7 wt%) + oxidized starch (0-6 wt%) were investigated as a function of pH. Samples prepared at 90 °C, with citric acid added to adjust the pH, were rapidly quenched to ∼1 °C, subjected to a standard thermal treatment (40 °C for 10 min), and then investigated by confocal microscopy and small-deformation rheology at 24 °C. Under ‘natural’ conditions of pH ≈ 5.2 (no citric acid addition), the samples exhibited phase separation with a characteristic spinodal-type morphology. The spatial extent of the structural heterogeneity, expressed by a single length-scale parameter, was found to increase with starch concentration. Gradual acidification led to a reduction in this length-scale parameter, leading to complete inhibition of phase separation below a certain characteristic pH value in the range 4.5-4.9 (depending on starch content). Over the investigated pH range, the effect of starch addition was to reduce the storage modulus of the resulting gel. This reduction was more pronounced for the phase-separated samples. The pH of maximum rigidity was found to decrease from pHmax ≈ 4.6 for 0 wt% starch to pHmax ≈ 4.2 for 6 wt% starch. Taken all together, these observations can be understood in terms of the effects of pH on the cross-linking behaviour of the gelatin and the nature of the gelatin-starch electrostatic interactions. The microscopy results are consistent with a transition in behaviour from thermodynamic incompatibility (segregative interactions) at high pH to soluble complexation (associative interactions) at low pH. 相似文献
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During electrical discharge machining (EDM), ablated workpiece material is rapidly solidified upon ejection into the dielectric and thought not to become reattached to the electrode surfaces. This work furthers the understanding of the little understood discharge gap phenomena by investigating the attachment of machined material back onto the tool electrode surface and explains the mechanism of this attachment. After the machining of high-aspect ratio slots, SEM and EDS techniques along with single discharge and cross-sectional analysis were used to explain that debris reattachment onto the tool electrode does not occur randomly but is dependent on its remelting in the dielectric by the secondary discharge process. The subsequently bonded material is present mainly in the centre of the discharge crater, with no attachment occurring outside of discharge affected regions. The surfaces of electrodes subject to intense secondary sparking are therefore liable to transient surface properties dependent on the composition of the deposited material. It is also observed that the deposited material on the tool electrode can offer a protective effect against wear from further secondary discharges and so potentially enhancing tool life. 相似文献
109.
Twenty-three strains of lactic acid enterococci isolated from dromedary raw milks in Southern Algeria were investigated for their proteolytic activity and ability to produce biogenic amines by decarboxylating amino acids: histidine, tyrosine and ornithine. All strains tested displayed proteolytic activities, but none of them were able to produce detectable biogenic amines in the usual adequate laboratory media, namely, Joosten and Northolt medium and Leuschner medium. Polymerase chain reaction experiments indicate a positive correlation between the absence of the hdc and odc genes and the lack of histamine and putrescine production for all tested strains. By contrast, all strains appeared to possess tdc gene, but no correlation was found with a negative expression of tyrosine decarboxylase.
In foods, biogenic amines are mainly generated by decarboxylation of the corresponding amino acids through substrate-specific enzymes of the microorganisms present in this environment, particularly histidine, tyrosine, lysine, ornithine and arginine, and the capability of enterococci and some other lactic acid bacteria to produce biogenic amines has been described. For this purpose, several qualitative and quantitative methods to determine biogenic amines production by these microorganisms have been developed. There is great interest to identify and to characterize the bacteria strains intended for an industrial use and to verify if they are potentially able to produce biogenic amines in order to prevent it's synthesis and limit the poisoning risk. 相似文献
PRACTICAL APPLICATIONS
In foods, biogenic amines are mainly generated by decarboxylation of the corresponding amino acids through substrate-specific enzymes of the microorganisms present in this environment, particularly histidine, tyrosine, lysine, ornithine and arginine, and the capability of enterococci and some other lactic acid bacteria to produce biogenic amines has been described. For this purpose, several qualitative and quantitative methods to determine biogenic amines production by these microorganisms have been developed. There is great interest to identify and to characterize the bacteria strains intended for an industrial use and to verify if they are potentially able to produce biogenic amines in order to prevent it's synthesis and limit the poisoning risk. 相似文献
110.
Malcolm R. Davidson Murray Rudman 《Numerical Heat Transfer, Part B: Fundamentals》2013,63(3-4):291-308
A new volume-of-fluid (VOF)-based numerical method for calculating heat transfer or mass transfer of a species within and between fluids with deforming interfaces is described. The algorithm is tested first against an analytical solution for diffusion from a sphere, and good agreement between theory and calculation is shown. The method is then demonstrated by predicting (a) heat transfer from a rising bubble when the bubble forms a toroidal shape, and (b) mass transfer from a rising drop when the drop phase controls diffusion. The method is shown to be a viable approach for complex interfacial heat/mass transfer. 相似文献