THE QUEST FOR WORLD CLASS IT CAPABILITY IT Is Key to Achieving Quality Goals

Abstract

In today's competitive world, many organizations are pursuing total quality improvement programs, and as a result of these initiatives, are seeking to define world class capabilities. The organizations with these aspirations are trying to improve product and service quality, business process quality, or delivered quality, and are becoming aware that information technology is playing a more substantial role in realizing these quality goals.     

Involving the user Through Library 2.0

Libraries, as we know them today, can be defined by the term Library 1.0. This defines the way resources are kept on shelves or at a computer behind a login. These resources can be taken from a shelf, checked out by the library staff, taken home for a certain length of time and absorbed, and then returned to the library for someone else to avail of. Library 1.0 is a one-directional service that takes people to the information they require. Library 2.0 – or L2 as it is now more commonly addressed as – aims to take the information to the people by bringing the library service to the Internet and getting the users more involved by encouraging feedback participation. This paper presents an overview of Library 2.0 and introduces web 2.0 concepts.     

Development and Deployment of an Intelligent Kite Aerial Photography Platform (iKAPP) for Site Surveying and Image Acquisition

Aerial photographs and images are used by a variety of industries, including farming, landscaping, surveying, and agriculture, as well as academic researchers including archaeologists and geologists. Aerial imagery can provide a valuable resource for analyzing sites of interest and gaining information about the structure, layout, and composition of large areas of land that would be unavailable otherwise. Current methods of acquiring aerial images rely on techniques such as satellite imagery, manned aircraft, or more recently unmanned aerial vehicles (UAVs) and micro‐UAV technologies. These solutions, while accurate and reliable, have several drawbacks. Using satellite imagery or UAVs can prove to be very expensive, costing tens of thousands for images. They can also prove to be time‐consuming and in some cases have constraints on use, such as no‐fly zones. In this paper, we present an alternative low‐cost, versatile solution to these methods, an intelligent kite aerial photography platform (iKAPP), for the purpose of acquiring aerial images and monitoring sites of interest. We show how this system provides flexibility in application, and we detail the system's design, mechanical operation, and initial flight experiments for a low‐cost, lightweight, intelligent platform capable of acquiring high‐resolution images. Finally, we demonstrate the system by acquiring images of a local site, showing how the system functions and the quality of images it can capture. The application of the system and its capabilities in terms of capture rates, image quality, and limitations are also presented. The system offers several improvements over traditional KAP systems, including onboard “intelligent” processing and communications. The intelligent aspect of this system stems from the use of self‐image stabilization of the camera, the advantage being that one is able to configure the system to capture large areas of a site automatically, and one can see the site acquisition in real time, all of which are not possible with previous methods of AP. © 2013 Wiley Periodicals, Inc.     

Siting park-and-ride facilities using a multi-objective spatial optimization model

Park-and-ride services are an important component of many public transportation systems in the United States. Locating park-and-ride facilities is an essential step when planning for these services. In this research we focus on three major siting/modeling concerns that need to be addressed when siting park-and-ride facilities: covering as much potential demand as possible, locating park-and-ride facilities as close as possible to major roadways, and siting such facilities in the context of an existing system. Unfortunately, existing models do not enable each of these concerns to be simultaneously addressed. This paper presents a multi-objective spatial optimization model for integrating these considerations. This model is applied for siting park-and-ride facilities in Columbus, Ohio. Application results show the usefulness of the developed model in supporting transit planning in an urban region.     

A cost-effective lexical acquisition process for large-scale thesaurus translation

Thesauri and controlled vocabularies facilitate access to digital collections by explicitly representing the underlying principles of organization. Translation of such resources into multiple languages is an important component for providing multilingual access. However, the specificity of vocabulary terms in most thesauri precludes fully-automatic translation using general-domain lexical resources. In this paper, we present an efficient process for leveraging human translations to construct domain-specific lexical resources. This process is illustrated on a thesaurus of 56,000 concepts used to catalog a large archive of oral histories. We elicited human translations on a small subset of concepts, induced a probabilistic phrase dictionary from these translations, and used the resulting resource to automatically translate the rest of the thesaurus. Two separate evaluations demonstrate the acceptability of the automatic translations and the cost-effectiveness of our approach.

Mammary gland expression of transgenes and the potential for altering the properties of milk

Transgenic animals are a useful in vivo experimental model for assessing the ability and impact of foreign gene expression in a biological system. Transgenic mice are most commonly used, while transgenic sheep, goats, pigs and cows have also been developed for specific, "applied" purposes. Most of the work directed at targeting expression of transgenes to the mammary gland of an animal, by using a milk gene promoter, has been with the intent of either studying promoter function or recovering the desired protein from the milk. Transgenic technology can also be used to alter the functional and physical properties of milk resulting in novel manufacturing properties. The properties of milk have been altered by adding a new protein with the aim of improving the milk, not of recovering the protein for other uses.     

Negative regulation by interleukin-3 (IL-3) of mouse early B-cell progenitors and stem cells in culture: transduction of the negative signals by betac and betaIL-3 proteins of IL-3 receptor and absence of negative regulation by granulocyte-macrophage colony-stimulating factor

The receptors for interleukin-3 (IL-3), granulocyte-macrophage colony-stimulating factor (GM-CSF), and IL-5 share a common signaling subunit betac. However, in the mouse, there is an additional IL-3 signaling protein, betaIL-3, which is specific for IL-3. We have previously reported that IL-3 abrogates the lymphoid potentials of murine lymphohematopoietic progenitors and the reconstituting ability of hematopoietic stem cells. We used bone marrow cells from betac- and betaIL-3-knock-out mice to examine the relative contributions of the receptor proteins to the negative regulation by IL-3. First, we tested the effects of IL-3 on lymphohematopoietic progenitors by using lineage-negative (Lin-) marrow cells of 5-fluorouracil (5-FU)-treated mice in the two-step methylcellulose culture we reported previously. Addition of IL-3 to the combination of steel factor (SF, c-kit ligand) and IL-11 abrogated the B-lymphoid potential of the marrow cells of both types of knock-out mice as well as wild-type mice. Next, we investigated the effects of IL-3 on in vitro expansion of the hematopoietic stem cells. We cultured Lin-Sca-1-positive, c-kit-positive marrow cells from 5-FU-treated mice in suspension in the presence of SF and IL-11 with or without IL-3 for 7 days and tested the reconstituting ability of the cultured cells by transplanting the cells into lethally irradiated Ly-5 congenic mice together with "compromised" marrow cells. Presence of IL-3 in culture abrogated the reconstituting ability of the cells from both types of knock-out mice and the wild-type mice. In contrast, addition of GM-CSF to the suspension culture abrogated neither B-cell potential nor reconstituting abilities of the cultured cells of wild-type mice. These observations may have implications in the choice of cytokines for use in in vitro expansion of human hematopoietic stem cells and progenitors.     

Engineering analysis of biological variables: an example of blood pressure over 1 day

Almost all variables in biology are nonstationarily stochastic. For these variables, the conventional tools leave us a feeling that some valuable information is thrown away and that a complex phenomenon is presented imprecisely. Here, we apply recent advances initially made in the study of ocean waves to study the blood pressure waves in the lung. We note first that, in a long wave train, the handling of the local mean is of predominant importance. It is shown that a signal can be described by a sum of a series of intrinsic mode functions, each of which has zero local mean at all times. The process of deriving this series is called the "empirical mode decomposition method." Conventionally, Fourier analysis represents the data by sine and cosine functions, but no instantaneous frequency can be defined. In the new way, the data are represented by intrinsic mode functions, to which Hilbert transform can be used. Titchmarsh [Titchmarsh, E. C. (1948) Introduction to the Theory of Fourier Integrals (Oxford Univ. Press, Oxford)] has shown that a signal and i times its Hilbert transform together define a complex variable. From that complex variable, the instantaneous frequency, instantaneous amplitude, Hilbert spectrum, and marginal Hilbert spectrum have been defined. In addition, the Gumbel extreme-value statistics are applied. We present all of these features of the blood pressure records here for the reader to see how they look. In the future, we have to learn how these features change with disease or interventions.