无荷载状况下泡沫混凝土裂缝控制的研究

研究了水胶比、粉煤灰、PP纤维和高性能膨胀剂对无荷载状况下泡沫混凝土力学性能、收缩性能的影响.结果表明,泡沫混凝土在水化中后期表现为收缩的特征;在水胶比为0.3～0.5时,水胶比越大,最终泡沫混凝土的收缩越小,当水胶比大于0.5或小于0.2时,28 d收缩量都减小.乱向分布的纤维可以略微减小泡沫混凝土的收缩;一定掺量的膨胀剂可以有效地补偿泡沫混凝土变形收缩,在水化早期实现泡沫混凝土无收缩.     

利用废弃混凝土制备半干压成型砖的研究

利用废弃混凝土制备了半干压成型砖,研究了养护制度和碱激活对半干压成型砖性能的影响.结果表明,随着养护温度的提高,半干压成型砖的强度逐渐增大;养护温度越高,半干压成型砖的最大强度也越高,达到最高强度所需的时间越短;当养护时间达到一临界值后,强度不再增长.碱激发可提高半干压成型砖的早期强度,但对半干压成型砖的后期强度没有影响.制备的半干压成型砖抗压强度和抗冻性等指标能够满足相关标准的要求,表明利用废弃混凝土制备半干压成型砖是可行的.     

安徽省城镇既有建筑外门外窗节能改造探讨

对安徽省城镇既有建筑外门外窗的节能现状进行了随机调查,分析了既有建筑外门外窗的热工环境及其对室内环境的影响.研究认为,外门外窗对建筑节能贡献最大,应是既有建筑节能改造、改善室内环境的重点;提出安徽省既有建筑外门外窗的节能改造须从外门外窗型的确定、框扇型材的选择、节能玻璃的选择、玻璃周边的密封及隔声等多方面入手,才能达到...     

实施民用建筑节能标准的经济和环境影响测算研究

建立了实施民用建筑节能标准的经济和环境影响测算模型.与以往的粗略估计不同,该模型将实施民用建筑节能标准与其引起的环境经济结构变化相联系,采用4个指标评价实施民用建筑节能标准的直接经济影响、5个指标评价直接环境影响、3个指标评价完全经济影响.在两种情境假定下,应用模型进行了测算.然后对模型中的主要参数和变量进行了敏感度分...     

A comparative study of the thermal stability of phenylalanyl tRNA synthetase from Escherichia coli MRE-600 and Thermus thermophilus HB 8

The thermal stability of phenylalanyl-tRNA-synthetase (PTS) from E. coli and T.thermophilus HB 8 was studied in solution at various conditions by scanning microcalorimetry. It has been shown that the value of heating rate, concentration of the enzyme and Mg2+ ions in the solution affects the parameters of thermal denaturation of both enzymes. The higher thermal stability of PTS from T. thermophilus was observed as well as the independence of its properties upon broad variations of experimental conditions. The role of thermostability of the enzymes are discussed with respect to the biological properties of E. coli and T.thermophilus.     

Comparison of metoprolol and sotalol in preventing ventricular tachyarrhythmias after the implantation of a cardioverter/defibrillator

The purpose of this prospective study was to evaluate, on an intention-to-treat basis, the efficacy of d,l-sotalol and metoprolol with regards to the recurrence of arrhythmic events after implantable cardioverter defibrillator (ICD) implantation. After ICD implantation, 70 patients were randomly assigned to treatment with either metoprolol (mean dosage 104+/-37 mg/day in 35 patients) or d,l-sotalol (mean dosage 242+/-109 mg/day in 35 patients). During follow up ventricular tachycardia (VT), fast VT, and ventricular fibrillation (VF) episodes were calculated. Metoprolol treatment led to a marked reduction in the recurrence of arrhythmic events. Actuarial rates for absence of VT recurrence at 1 and 2 years were significantly higher in the metoprolol group compared with the d,l-sotalol group (83% and 80% vs 57% and 51%, respectively, p=0.016). The actuarial rates for absence of fast VT or VF were 80% in the metoprolol group compared with 46% in the d,l-sotalol group (p=0.002). During a follow up of 26+/-16 months, there were 3 deaths in the metoprolol group compared with 6 deaths in the d,l-sotalol group. Actuarial rates of overall survival were not significantly different in the 2 groups (91% vs 83%, p=0.287). In this prospective, randomized, controlled study the recurrence rate of ventricular tachyarrhythmias in patients treated with metoprolol was lower than in patients treated by d,l-sotolol.     

A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes

The protein product of the c-Cbl proto-oncogene is prominently tyrosine phosphorylated in response to insulin in 3T3-L1 adipocytes and not in 3T3-L1 fibroblasts. After insulin-dependent tyrosine phosphorylation, c-Cbl specifically associates with endogenous c-Crk and Fyn. These results suggest a role for tyrosine-phosphorylated c-Cbl in 3T3-L1 adipocyte activation by insulin. A yeast two-hybrid cDNA library prepared from fully differentiated 3T3-L1 adipocytes was screened with full-length c-Cbl as the target protein in an attempt to identify adipose-specific signaling proteins that interact with c-Cbl and potentially are involved in its tyrosine phosphorylation in 3T3-L1 adipocytes. Here we describe the isolation and the characterization of a novel protein that we termed CAP for c-Cbl-associated protein. CAP contains a unique structure with three adjacent Src homology 3 (SH3) domains in the C terminus and a region showing significant sequence similarity with the peptide hormone sorbin. Both CAP mRNA and proteins are expressed predominately in 3T3-L1 adipocytes and not in 3T3-L1 fibroblasts. CAP associates with c-Cbl in 3T3-L1 adipocytes independently of insulin stimulation in vivo and in vitro in an SH3-domain-mediated manner. Furthermore, we detected the association of CAP with the insulin receptor. Insulin stimulation resulted in the dissociation of CAP from the insulin receptor. Taken together, these data suggest that CAP represents a novel c-Cbl binding protein in 3T3-L1 adipocytes likely to participate in insulin signaling.     

Community respiratory viral infection in adult lung transplant recipients

STUDY OBJECTIVE: To define the epidemiology, clinical manifestations, and long-term complications of respiratory viral infections in adult lung transplant recipients. DESIGN: Retrospective review of the records of 122 adult lung transplant recipients over a 5-year period at one institution. RESULTS: Ten episodes of infection with respiratory syncytial virus, parainfluenza, influenza, or adenovirus were identified. All patients presented with symptoms of respiratory tract infection. Two patients died acutely and four patients subsequently had development of obliterative bronchiolitis (OB). CONCLUSIONS: These data suggest community respiratory viral infections cause significant morbidity and mortality in lung transplant recipients. Further prospective studies are warranted to clarify the relationship between respiratory viral infection and OB and to define the optimal therapy for these viral infections.