The interaction of atrial natriuretic peptide with other bioregulators of kidney function in chronic glomerulonephritis in children

A study was made of renin-angiotensin-aldosterone system activity and plasmic concentrations of atrial natriuretic peptide (NUP) as well as antidiuretic hormone in children with primary glomerulonephritis. A close relationship was established of these parameters in regulation of water-salt homeostasis. The above systems are involved in pathogenesis of childhood glomerulonephritis. This finding should be considered in development of pathogenetically validated therapy of glomerulonephritis, including introduction of synthetic NUP.     

The participation of the serotonin link in the neurochemical mechanism of transcranial electroanalgesia

Metergoline and 5, 7-dihydroxytryptamine were found to suppress and to prevent an electroanalgesic effect, resp. An increase in the serotonine contents in the CSF after electroanalgesia suggests an activation of the brain serotoninergic system. DL-5-hydroxytryptophan and allopurinol enhanced the electroanalgetic effect. The data obtained suggests an existence of a serotoninergic component of the transcranial electroanalgesia mechanism.     

The P-H-T effects on the electric resistance and magnetoresistance of La0.7Sr0.1Pb0.2MnO3 single crystal films

The effects of high hydrostatic pressures (P) and magnetic fields (H) in a broad temperature range (T=77–325 K) on the electric resistance (R) and magnetoresistance (ΔR/R ₀) was studied in laser-deposited La_0.7Sr_0.1Pb_0.2MnO₃ single crystal films on (100)-oriented SrTiO₃ substrates. A maximum response to the P and H variations was observed in the temperature interval of phase transitions (T=310–325 K). A growth in the pressure P leads to an increase in both R and ΔR/R ₀ values, while an increase in the magnetic field strength H is accompanied by an increase in ΔR/R ₀ and a drop in the electric resistance R of the single crystal films studied.     

Nonlinear parametric identification of stochastic discrete plants based on generalized probabilistic criteria

Studying alternative (with respect to conventional) methods of stochastic parameter identification of nonlinear discrete plants is shown to be of current interest. For the first time, generalized probabilistic criteria for discrete time are proposed to solve the problem of parametric identification of nonlinear stochastic plants. A parametric identification algorithm is proposed based on the criterion of the minimum probability of estimation error. A toy example is considered to illustrate the efficiency of the proposed approach.     

Effect of different modifications of BEA-zeolites on operational characteristics of conductometric biosensor

Effect of different modifications of zeolite Na⁺-BEA on working characteristics of urease-based conductometric biosensor was studied. As the biosensor sensitive elements were used bioselective membranes based on urease and various zeolites immobilised with bovine serum albumin on the surface of conductometric transducers. Influence of zeolites on sensitivity of urea biosensor was investigated as well as reproducibility of biosensor signal and reproducibility of activity of the bioselective element after different variants of urease immobilisation on the surface of conductometric transducer. The biosensors based on zeolites (NH₄⁺-BEA 30 and H⁺-BEA 30) were shown to be the most sensitive. Concentration of these zeolites in the bioselective membrane was optimized. Use of zeolites modified with methyl viologen and silver was ascertained to be of no prospect for urea conductometric biosensors. It was demonstrated that characteristics of urea biosensors can be regulated, varying zeolites modifications and their concentrations in bioselective membranes.     

Combined reprocessing of weapons plutonium into high-purity oxide fuel

The main results of a study of regimes for dissolution of plutonium oxide and mononitride powders, obtained by the pyrochemical method from weapons plutonium, in acids for subsequent extraction removal of gallium, americium, and ballast impurities and obtaining ceramic-type plutonium oxide powder suitable for fabricating mixing oxide fuel are presented. It is established experimentally that plutonium oxide and mononitride obtained by the pyrochemical method dissolve rapidly in the acid mixture HNO₃ 12 moles/liter and HF 0.1 moles/liter. Plutonium extraction into solution reaches >99%.