An overview of FDA medical device regulation as it relates to deep brain stimulation devices.

The United States Food and Drug Administration (FDA) is charged with assuring the safety and effectiveness of a variety of medical products and the FDA's Center for Devices and Radiological Health is responsible for premarket and postmarket regulation of medical devices. In this paper, we review--from device classification and clinical studies to the final marketing application--FDA's premarket requirements and postmarket requirements as they relate to deep brain stimulation devices.     

Phase transmittance RBF neural networks

Presented is a new complex valued radial basis function (RBF) neural network with phase transmittance between the input nodes and output, which makes it suitable for channel equalisation on quadrature digital modulation systems.     

Cyclic variations in the permeability of the cell wall of Saccharomyces cerevisiae.

To study cell-cycle-related variations in wall permeability of Saccharomyces cerevisiae, two approaches were used. First, an asynchronous culture was fractionated by centrifugal elutriation into subpopulations containing cells of increasing size. The subpopulations represented different stages of the cell cycle as judged by light microscopy. Cell wall porosity increased when these subpopulations became enriched with budded cells. Secondly, synchronous cultures were obtained by releasing MATa cells from alpha-factor induced G1-arrest. These cultures grew synchronously for at least two generations. The cell wall porosity increased sharply in these cultures, shortly before buds became visible and was maximal during the initial stages of bud growth. It decreased in cells which had completed nuclear migration and before abscission of the bud had occurred. The porosity reached its lowest value during abscission and in unbudded cells. We examined the incorporation of mannoproteins into the wall during the cell cycle. SDS-extractable mannoproteins were incorporated continuously. However, the incorporation of glucanase-extractable mannoproteins, which are known to affect cell wall porosity, showed cyclic oscillations and reached its maximum after nuclear migration. This coincided with a rapid decrease in cell wall porosity, indicating that glucanase-extractable mannoproteins might contribute to this decrease.     

明渠湍流床面附近跃移层面颗粒浓度垂线分布

本文以动理学理论的Boltzmann方程为基础，考虑明渠湍流床面附近猝发喷射和清扫运动对跃移层内运动颗粒的不同作用，分析了明渠中泥沙颗粒浓度垂线分布问题，得到了适用于包括跃移层、悬移层在内的统一浓度垂线分布公式。文中着重研究了跃移层内运动颗粒的浓度垂线分布，并将本文结果与实测跃移层内浓度垂线分布及实测跃移层顶部浓度进行了对比，结果表明理论与实验两者符合较好。     

彩色等离子体显示器的新进展

扼要地介绍了近年来世界上各大公司对彩色PDP的结构和驱动方法的改进 ,将现今彩色PDP的亮度、对比度和色纯度等主要性能与过去相比 ,得到明显的改善 ,达到了与高清晰度CRT相当的性能。     

锅炉炉膛红外成像温度实时检测系统研究

说明电厂锅炉炉膛温度及结焦直接影响锅炉正常运行及安全；给出了基于多探测器的锅炉反应温度红外成像实时测温系统的系统结构、系统原理、系统标定和温度测定方法。     

手套箱气氛中氚化水处理的工艺研究

分子筛吸附柱和热金属镁床是手套箱气氛中氚化水 (HTO)搜集和分解处理的一种有效手段。测试了分子筛柱对气氛中水的吸附性能和热金属镁床对HTO的分解性能。结果表明 :分子筛柱对气氛中水的吸附效率 >99 99% ,在空气中水含量为 3 4× 1 0 - 3～ 4 2× 1 0 - 3条件下 ,未发现吸附柱水的贯穿现象 ;热金属镁床对HTO的分解率 >99 9% ,当金属镁的消耗量大于 80 %时 ,未见分解率明显降低。     

A variational approach to magnetoelastic buckling problems for systems of superconducting tori

A variational principle for the magnetoelastic stability problem of superconductors is constructed. Independently, a pair of integral equations is derived, from which the initial and the perturbed field can be computed. The integral equations are solved for in-plane buckling of a slender pair of concentric tori, and out-of-plane buckling of a slender pair of equal coaxial tori. By using the variational principle, it is shown that both cases can become unstable when the currents on the two tori are equally directed, and the pertinent buckling values are calculated. The thus obtained buckling values are compared with the results of an alternative, mathematically less rigorous, method. A good correspondence between the two methods is found (at least as long as the two tori are not too near).     

DNA/lipid complex organogel with shape‐memory behavior

DNA and amphiphilic N,N,N‐trimethyl‐N‐hexadecylammonium bromide (THAB) were stoichiometrically mixed together to produce a DNA–lipid complex, which was dissolved in dimethyl sulfoxide (DMSO) at 65°C and then crosslinked with isophorone diisocyanate (IPDI). The obtained organogel swelled reversibly in DMSO, responding to the variation of temperature. Interestingly, we observed that the gel exhibited a temperature‐dependent shape‐memory behavior. Above 65°C, whatever the shape the gel was deformed to, it could retain the new shape as the temperature was decreased to room temperature, while, when the gel was heated to 65°C again, it could recover its initial shape. The shape‐memory characteristic is supposedly originated from the transition between the close‐packed and the destroyed DNA/lipid conformation. The elastic urethane crosslinking bonds between base‐pair sites act as a fixing phase. The gel holds promise in its application as a gentle actuator. © 2002 Wiley Periodicals, Inc. J Appl Polym Sci 86: 259–263, 2002