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51.
This paper provides a thorough review of the current state-of-the-art within airline disruption management of resources, including aircraft, crew, passenger and integrated recovery. An overview of model formulations of the aircraft and crew scheduling problems is presented in order to emphasize similarities between solution approaches applied to the planning and recovery problems. A brief overview of research within schedule robustness in airline scheduling is included in the review, since this proactive measure is a natural complement to disruption management.  相似文献   
52.
The need to recover a train driver schedule occurs during major disruptions in the daily railway operations. Based on data from the Danish passenger railway operator DSB S-tog A/S, a solution method to the train driver recovery problem (TDRP) is developed. The TDRP is formulated as a set partitioning problem. We define a disruption neighbourhood by identifying a small set of drivers and train tasks directly affected by the disruption. Based on the disruption neighbourhood, the TDRP model is formed and solved. If the TDRP solution provides a feasible recovery for the drivers within the disruption neighbourhood, we consider that the problem is solved. However, if a feasible solution is not found, the disruption neighbourhood is expanded by adding further drivers or increasing the recovery time period. Fractional solutions to the LP relaxation of the TDRP are resolved with a constraint branching strategy using the depth-first search of the Branch & Bound tree. The LP relaxation of the TDRP possesses strong integer properties. We present test scenarios generated from the historical real-life operations data of DSB S-tog A/S. The numerical results show that all but one tested instances produce integer solutions to the LP relaxation of the TDRP and solutions are found within a few seconds.  相似文献   
53.
In this paper we study parallel batch scheduling problems with bounded batch capacity and equal-length jobs in a single and parallel machine environment. It is shown that the feasibility problem 1|p-batch,b<n,r j ,p j =p,C j d j |− can be solved in O(n 2) time and that the problem of minimizing the maximum lateness can be solved in O(n 2log n) time. For the parallel machine problem P|p-batch,b<n,r j ,p j =p,C j d j |− an O(n 3log n)-time algorithm is provided, which can also be used to solve the problem of minimizing the maximum lateness in O(n 3log 2 n) time.  相似文献   
54.
Existing empirical studies on test-driven development (TDD) report different conclusions about its effects on quality and productivity. Very few of those studies are experiments conducted with software professionals in industry. We aim to analyse the effects of TDD on the external quality of the work done and the productivity of developers in an industrial setting. We conducted an experiment with 24 professionals from three different sites of a software organization. We chose a repeated-measures design, and asked subjects to implement TDD and incremental test last development (ITLD) in two simple tasks and a realistic application close to real-life complexity. To analyse our findings, we applied a repeated-measures general linear model procedure and a linear mixed effects procedure. We did not observe a statistical difference between the quality of the work done by subjects in both treatments. We observed that the subjects are more productive when they implement TDD on a simple task compared to ITLD, but the productivity drops significantly when applying TDD to a complex brownfield task. So, the task complexity significantly obscured the effect of TDD. Further evidence is necessary to conclude whether TDD is better or worse than ITLD in terms of external quality and productivity in an industrial setting. We found that experimental factors such as selection of tasks could dominate the findings in TDD studies.  相似文献   
55.
The pathogenesis of progressive renal allograft injury, which is termed chronic allograft nephropathy (CAN), remains obscure and is currently defined by histology. Prospective protocol-biopsy trials have demonstrated that clinical and standard laboratory tests are insufficiently sensitive indicators of the development and progression of CAN. The study aim was to determine if CAN could be characterized by urinary proteomic data and identify the proteins associated with disease. The urinary proteome of 75 renal transplant recipients and 20 healthy volunteers was analyzed using surface enhanced laser desorption and ionization MS. Patients could be classified into subgroups with normal histology and Banff CAN grades 2-3 with a sensitivity of 86% and a specificity of 92% by applying the classification algorithm Adaboost to urinary proteomic data. Several urinary proteins associated with advanced CAN were identified including α1-microglobulin, β2-microglobulin, prealbumin, and endorepellin, the antiangiogenic C-terminal fragment of perlecan. Increased urinary endorepellin was confirmed by ELISA and increased tissue expression of the endorepellin/perlecan ratio by immunofluoresence analysis of renal biopsies. In conclusion, analysis of urinary proteomic data has further characterized the more severe CAN grades and identified urinary endorepellin, as a potential biomarker of advanced CAN.  相似文献   
56.
The popularity of the iris biometric has grown considerably over the past two to three years. Most research has been focused on the development of new iris processing and recognition algorithms for frontal view iris images. However, a few challenging directions in iris research have been identified, including processing of a nonideal iris and iris at a distance. In this paper, we describe two nonideal iris recognition systems and analyze their performance. The word "nonideal" is used in the sense of compensating for off-angle occluded iris images. The system is designed to process nonideal iris images in two steps: 1) compensation for off-angle gaze direction and 2) processing and encoding of the rotated iris image. Two approaches are presented to account for angular variations in the iris images. In the first approach, we use Daugman's integrodifferential operator as an objective function to estimate the gaze direction. After the angle is estimated, the off-angle iris image undergoes geometric transformations involving the estimated angle and is further processed as if it were a frontal view image. The encoding technique developed for a frontal image is based on the application of the global independent component analysis. The second approach uses an angular deformation calibration model. The angular deformations are modeled, and calibration parameters are calculated. The proposed method consists of a closed-form solution, followed by an iterative optimization procedure. The images are projected on the plane closest to the base calibrated plane. Biorthogonal wavelets are used for encoding to perform iris recognition. We use a special dataset of the off-angle iris images to quantify the performance of the designed systems. A series of receiver operating characteristics demonstrate various effects on the performance of the nonideal-iris-based recognition system.  相似文献   
57.
A new diagnostic method to determine fibrinogen and fibrin splitting products is based on the fact that high-molecular fragments acting as specific inhibitors of fibrin self-assembly compose these products. Fibrinogen and fibrin splitting products are detected and determined quantitatively by prolongation of coagulation time in the test with the standard monomeric fibrin. The number of units of anticoagulating activity in the studied urine are the results of the determinations. Sensitivity of the method if necessary may be increased by adding of a certain amount of the fibrinogen and fibrin splitting products to the test that makes a favourable background for the action of the products. The method is rather sensitive, reliable and simple. It may be used in ordinary clinical laboratories. The method proved to be quite satisfactory when testing renal diseases at the clinic. It is of great significance for early detection of the transplanted kidney rejection. The new method is compared with the known immunological method which consist in determination of the inhibitory effect of the fibrinogen and fibrin splitting products on agglutination of erythrocytes of specific antibodies; the erythrocytes being subjected to "tanning" and "loading" with fibrinogen. A satisfactory correlation is found between the results of two methods.  相似文献   
58.
A new method for measuring the flux density and fluence of fast neutrons in a RBMK core, using a threshold ionization fission chamber with a 238U radiator, and a computational-experimental method based on threshold chambers for fissioning of 238U with enrichment at least 99.999% are proposed. A method is proposed for taking account of the correction factors for the change in sensitivity of threshold fission chambers with and without screens on the basis of RBMK-1000 fast-neutron spectra determined experimentally by the activation method.__________Translated from Atomnaya Energiya, Vol. 98, No. 4, pp. 260–267, April, 2005.  相似文献   
59.
We consider the multiple-depot multiple-vehicle-type scheduling problem (MDVSP) which arises in public transport bus companies and aims to assign buses to cover a given set of timetabled trips with consideration of practical requirements, such as multiple depots and vehicle types as well as depot capacities. An optimal schedule is characterized by minimal fleet size and minimal operational costs including costs for empty movements and waiting time. It is well-known that the MDVSP is NP-hard.Although progress has recently been made in solving large practical MDVSP to optimality with time-space network models, current optimization technology sets limits to the model size that can be solved. In order to approach very large practical instances we propose a two-phase method which produces close to optimal solutions. This modeling approach enables us to solve real-world problem instances with thousands of scheduled trips by direct application of standard optimization software. Furthermore, we introduce the concept of depot groups for the case that a bus may return in the evening into another depot than where it started in the morning.  相似文献   
60.
Exploratory spatio-temporal visualization: an analytical review   总被引:2,自引:0,他引:2  
Current software tools for visualization of spatio-temporal data, on the one hand, utilize the opportunities provided by modern computer technologies, on the other hand, incorporate the legacy from the conventional cartography. We have considered existing visualization-based techniques for exploratory analysis of spatio-temporal data from two perspectives: (1) what types of spatio-temporal data they are applicable to; (2) what exploratory tasks they can potentially support.The technique investigation has been based on an operational typology of spatio-temporal data and analytical tasks we specially devised for this purpose. The result of the study is a structured inventory of existing exploratory techniques related to the types of data and tasks they are appropriate for. This result is potentially helpful for data analysts—users of geovisualization tools: it provides guidelines for selection of proper exploratory techniques depending on the characteristics of data to analyze and the goals of analysis. At the same time the inventory as well as the suggested typology of tasks could be useful for tool designers and developers of various domain-specific geovisualization applications. The designers can, on the one hand, see what task types are insufficiently supported by the existing tools and direct their creative activities towards filling the gaps, on the other hand, use the techniques described as basic elements for building new, more sophisticated ones. The application developers can, on the one hand, use the task and data typology in the analysis of potential user needs, on the other hand, appropriately select and combine existing tools in order to satisfy these needs.  相似文献   
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