Permalloy-coated tungsten probe for magnetic manipulation of micro droplets

In this work, we present the magnetic manipulation of biocompatible droplets using a probe-based approach. First, we describe a simple method to develop magnetic probes that are capable of delivering localized magnetic fields, which is important for precise manipulation. The fabrication of magnetic probes involves controlled electroplating of permalloy (Ni₈₀Fe₂₀) on commercially available tungsten needles with tip radii as small as 0.5 μm. Experimental validation of probe functionality was achieved by characterizing the magnetic response of the probe with a highly sensitive scanning Hall probe system. The magnetic probe was then employed in manipulating biocompatible alginate micro droplets with encapsulated magnetic particles. The synthesis of the droplets was carried out in-house and droplets of different sizes and magnetic particle concentrations were obtained for use in manipulation experiments. Multiple experiments were done to demonstrate the efficacy of the developed probe in manipulating droplets, which is crucial for constructing droplet-based microfluidic systems.     

Use of nano-scale double-gate MOSFETs in low-power tunable current mode analog circuits

Use of independently-driven nano-scale double gate (DG) MOSFETs for low-power analog circuits is emphasized and illustrated. In independent drive configuration, the top gate response of DG-MOSFETs can be altered by application of a control voltage on the bottom gate. We show that this could be a powerful method to conveniently tune the response of conventional CMOS analog circuits especially for current-mode design. Several examples of such circuits, including current mirrors, a differential current amplifier and differential integrators are illustrated and their performance gauged using TCAD simulations. The topologies and biasing schemes explored here show how the nano-scale DG-MOSFETs may pave way for efficient, mismatch-tolerant and smaller circuits with tunable characteristics.     

The false positive effect of residue of sulphur sources on dithiocarbamate analysis based on CS2 measurement

Turkey plays an important role in the international trade of apricots as it has the largest production rate in the world. Since the sulphurisation process is allowed to be used for different products, the effect of residual sulphur and its compounds (which can be found in products as pesticide residues or additive residues) on the positive detection of carbon disulphide (CS₂) still creates a big challenge in international trade. Therefore, the main objective of the present study was to investigate the effects of residues of sulphur or sulphur compounds on dithiocarbamate analysis methods based on CS₂ measurement. In this study, apricots were chosen since they contain sulphur residues as a result of the sulphurisation process. Sulphur dioxide and dithiocarbamate analyses were conducted on dried apricots prepared with the sulphurisation process (SA) and without the sulphurisation process (NSA); analysis was by two different accredited laboratories. No of pesticide was applied to either SA or NSA samples. Although some of the NSA samples had <LOQ values, approximately 70 ± 32 mg/kg SO₂ and 0.061 ± 0.021 mg/kg dithiocarbamate were detected for NSA samples. On the other hand, for the SA sample group, 927–2915 mg/kg of SO₂ and 0.265–0.825 mg/kg of dithiocarbamate were detected. Furthermore, a strong correlation between residual sulphur and dithiocarbamate values was observed. This study showed that the analysis method based on CS₂ measurement may lead to false positive results for dithiocarbamates when residues of sulphur or sulphur compounds are found in products as pesticide or additive residues. Therefore, residual sulphur compounds as a result of the sulphurisation process (which is not considered during the evaluation of products) must be taken into account during the evaluation of products for dithiocarbamates.     

Progress in modification of sunflower oil to expand its industrial value

Increasing the sunflower seed oil content as well as improving its quality makes it compatible for industrial demands. This is an important breeding objective of sunflower which increases its market value and ensures high returns for the producers. The present review focuses on determining the progress of improving sunflower seed oil content and modifying its quality by empirical and advanced molecular breeding methods. It is known that the sunflower oil content and quality have been altered through empirical selection methods and mutation breeding programmes in various parts of the world. Further improvement in seed oil content and its components (such as phytosterols, tocopherols and modified fatty acid profile) has been slowed down due to low genetic variation in elite germplasm and complex of hereditary traits. Introgression from wild species can be carried out to modify the fatty acids profile and tocopherol contents with linkage drags. Different transgenes introduced through biotechnological methods may produce novel long‐chain fatty acids within sunflower oil. Bio‐engineering of sunflower oil could allow it to be used in diverse industrial products such as bio‐diesel or bio‐plastics. These results showed that past and current trends of modifying sunflower oil quality are essential for its further expansion as an oilseed crop. © 2017 Society of Chemical Industry     

Modelling 3D spatial enclosure of urban open spaces

Existing urban open space typologies within dense urban fabrics cannot meet society’s open space requirements in developing countries’ metropolitan cities, such as Istanbul. Because of high building densities, it is a challenging task to create new open spaces within urban cores. Developing new tools that work with the existing built environment is crucial to reveal ‘opportunity spaces’ that can act as breathing points within dense urban fabrics. In this research, a new model is developed to evaluate the 3D spatial enclosure of open spaces using basic geometrical properties and geographic information system (GIS) tools. As a case study, Istanbul’s changing spatial organization is analyzed using this model.     

Fracture analysis of anisotropic materials using enriched crack tip elements

Enriched finite element methodology, which employs special crack tip elements, is extended for cracks in anisotropic materials. Enrichment formulation is described briefly and three validation examples using single crystal, directionally solidified, and orthotropic material properties are presented to demonstrate the accuracy and effectiveness of the methodology. In addition to validation examples, the effect of material anisotropy on stress intensity factors is investigated using the common compact tension specimen and the results are compared to the ASTM solution for isotropic materials. It is shown that the effect of anisotropy on the computed stress intensity factors can be significant, depending on the degree of anisotropy, material orientation, and a/W ratio in the compact tension specimen geometry.     

Exploration of Na<Superscript>+</Superscript>,K<Superscript>+</Superscript>-ATPase ion permeation pathways <Emphasis Type="Italic">via</Emphasis> molecular dynamic simulation and electrostatic analysis

Biologically-inspired nanodevices can serve as “natural” alternatives to conventional semiconductor devices in many applications from information storage to mechanical rotors. In this work we consider an ATP-powered transmembrane protein, the Na⁺,K⁺-ATPase, which has appealing functionality but still lacks an “atomistic” picture capable of elucidating its operation. The vast collection of experimental literature on the Na⁺,K⁺-ATPase gives a unique advantage to this protein in developing and validating computational tools. We have performed extensive molecular dynamic simulations of the Na⁺,K⁺-ATPase in an accurate biological environment, followed by time-averaged electrostatic analysis, to investigate the ion-binding loci and access/egress pathways that cations may take through the protein as they are transported across the membrane.     

An elastic–plastic and residual stress analysis steel reinforced thermoplastic composite cantilever beam

In the present study an analytical elastic–plastic stress analysis is carried out for a low-density homogeneous polyethylene thermoplastic cantilever beam reinforced by steel fibers. The beam is loaded by a constant single force at its free end. The expansion of the region and the residual stress component of σ_x are determined for 0°, 15°, 30°, 45°, 60°, 75° and 90° orientation angles. Yielding begins for 0° and 90° orientation angles at the upper and lower surfaces of the beam at the same distances from the free end. Although it starts first at the upper surface for 15°, 30° and 45°, it starts first at the lower surface for 60° and 75° orientation angles. The elastic–plastic analysis is carried out for both the plastic region which spreads only at the upper surface and the plastic region which spreads at the upper and lower surfaces together. The residual stress components of σ_x and τ_xy are also determined. The intensity of the residual stress component is maximum at the upper and lower surfaces of the beam, but the residual stress component of τ_xy is maximum on or around the х-axis. The beam can be strengthened by using the residual stresses. The distance between the plastically collapsed point and the free end is calculated for the same load in the beam for 0°, 15°, 30°, 45°, 60°, 75° and 90° orientation angles.     

Discharge Capacity of Labyrinth Side Weir Located on a Straight Channel

Side weirs, also known as lateral weirs, are flow diversion devices widely used in irrigation as a head regulator of distributaries and escapes, land drainage, and urban sewage systems. The studies on the subject have been generally focused on rectangular and triangular side weirs located on a straight channel. However, the same is not true for labyrinth side weirs. The current studies deal with sediment transport and scour problems around side weirs and lateral structures. The investigation of the hydraulic effects of labyrinth side weirs to increase discharge capacity of them has been studied in this particular work. In the study, 2,830 laboratory tests were conducted for determining discharge coefficient of labyrinth side weirs, and results were analyzed to find the influence of the dimensionless weir length L/b, the dimensionless effective length L/?, the dimensionless weir height p/h1, triangular labyrinth side weir included angle θ, and upstream Froude number F1 on the discharge coefficient, water surface profile and velocities in the channel along the side weir. It has been found that discharge coefficient of labyrinth side weirs gives pretty higher coefficient value compare to that of classical side weirs and a reliable equation for discharge coefficient of labyrinth weirs is presented. Discharge coefficient of the labyrinth side weir is 1.5–4.5 times higher than rectangular side weir.