A study on the interaction between ibuprofen and bilayer lipid membrane

Ibuprofen is a well-known nonsteroidal anti-inflammatory drug, which can interact with lipid membranes. In this paper, the interaction of ibuprofen with bilayer lipid membrane was studied by UV-vis spectroscopy, cyclic voltammetry and AC impedance spectroscopy. UV-vis spectroscopy data indicated directly that ibuprofen could interact with lipid vesicles. In electrochemical experiments, ibuprofen displayed a biphasic behavior on bilayer lipid membrane supported on a glassy carbon electrode. It could stabilize the lipid membrane in low concentration, while it induced defects formation, even removed off bilayer lipid membrane from the surface of the electrode with increasing concentration. The mechanism about the interaction between ibuprofen and supported bilayer lipid membrane was discussed.     

远洋山水居住区(西区)"九年一贯制"学校

远洋山水居住区（西区）的教育优势突出，在居住区的西南角规划设计了一所36班的“九年一贯制”示范学校。其中，小学部24班，初中部12班。该学校隶属于石景山教委，主要招生服务对象为远洋山水居住区（西区）和周边社区的居民。学校占地3.6ha，总建筑面积约23800m^2。     

天康面粉公司制粉车间局部技改介绍

山东巨野国家粮食储备库天康面粉公司制粉车间始建于2000年,设计能力为处理小麦100t/d.主要设备有FMFQ10×2/6×2磨粉机8台,FS-FG6×24C高方筛3台,FQFD50×2×3清粉机2台,磨辊总接触长度12000 mm,平筛总筛理面积138.8 m2,单位磨辊接触长度12 mm/(100kg·d),单位平筛筛理面积0.14 m2/(100kg·d).麦间清理工艺(包括初清)为4筛2打2去石3磁选2着水,粉间工艺为488M1S2T4P3Br.     

Transformations in machining. Part 1. enhancement of wavelet transformation neural network (WT-NN) combination with a preprocessor

Properly selected transformation methods obtain the most significant characteristics of metal cutting data efficiently and simplify the classification. Wavelet Transformation (WT) and Neural Networks (NN) combination was used to classify the experimental cutting force data of milling operations previously. Preprocessing (PreP) of the approximation coefficients of the WT is proposed just before the classification by using the Adaptive Resonance Theory (ART2) type NNs. Genetic Algorithm (GA) was used to estimate the weights of each coefficient of the PreP. The WT-PreP-NN (ART2) combination worked at lower vigilances by creating only a few meaningful categories without any errors. The WT-NN (ART2) combination could obtain the same error rate only if very high vigilances are used and many categories are allowed.     

Ten-user truly asynchronous gigabit OCDMA transmission experiment with a 511-chip SSFBG en/decoder

A ten-user truly asynchronous gigabit coherent-optical-code-division-multiple-access (OCDMA) transmission was experimentally demonstrated without using any timing coordination. The enabling technologies are a record-length 511-chip superstructured-fiber-Bragg-grating (SSFBG) en/decoder and a supercontinuum (SC)-based optical-thresholding technique to significantly suppress the signal interference beat noise as well as the multiple-access-interference (MAI) noise.     

基于DTC的井下架线式电机车变频调速装置设计与应用

分析了井下架线式电机车运行现状及存在的维护量大、维护成本高、故障率高等问题.设计了一种基于DTC的电机车电机变频调速装置,现场应用情况表明其具有起动力矩大、维护量小、故障率低、节约成本的优点.指出了应用DTC变频调速技术改造传统的矿用架线式电机车直流传动系统的必要性及应用前景.     

A physically based approach to granular media mechanics: grain-scale experiments,initial results and implications to numerical modeling

It is generally appreciated that the mechanical behavior of granular media depends fundamentally on the interaction of the constituent particles, and that the validity of numerical models of granular media would be greatly improved with knowledge of the grain-scale mechanics. However, most supporting experimental work has been conducted on highly idealized materials, and a limited amount of information exists on grain-scale force–displacement relationships for naturally occurring materials. To address this shortcoming, we are conducting a program that integrates laboratory experiments on grains of naturally occurring aggregate with the discrete element modeling method, with the goal of relating the grain-scale physical and mechanical properties of granular media to bulk behavior. The paper describes the equipment and methods that have been developed to conduct close-loop controlled, grain-scale experiments under monotonic and cyclic loading conditions, and presents results from an initial set of experiments on unbonded grains. The implications of the grain-scale results to the discrete element model are discussed. Discussions center on the applicability of a physically based approach to the mechanics of granular media in general. In light of future exploration missions and the resulting need to predict the mechanical properties of lunar and planetary regoliths, the paper examines the potential usefulness of our physically based approach to the problem of predicting the behavior of the types of materials found in those environments.     

辐射敏感综合症--AT病研究进展

共济失调性毛细血管扩张综合症(AT)是一种单基因突变引起的遗传性疾病，表现为高辐射敏感性、进行性神经退变、免疫缺陷、早衰及易患癌症等。本文综述了AT病的研究概况，包括AT临床症状、AT基因的定位、结构与功能、辐射对AT细胞信号传导的影响、AT基因组不稳定性及基因治疗。