The use of notch and short crack approaches to fretting fatigue threshold prediction: Theory and experimental validation

In this paper the similarities between fretted and notched components in terms of stress gradient and the consequent “size effect” are discussed. Critical distance and short crack arrest approaches for the prediction of fretting fatigue thresholds are then presented and the predictions are compared with experimental results. Two geometry and alloy combinations are considered in order to validate the prediction by the means of experimental results. In particular, both Hertzian fretting tests performed on Al4%Cu alloys and experiments carried out employing ‘flat and rounded’ contact pads, made of Ti6Al4V alloy, are used for the comparison. It is shown that both criteria provide good predictive capabilities. However, the short crack arrest method is less empirical and can be adapted to a wider range of applications (e.g. surface treated components).     

Performance of smart lightwave receivers with linear equalization

Signal processing techniques can be used to reduce linear and nonlinear distortion in high-speed lightwave systems caused by fiber dispersion and nonideal responses of optoelectronic and electronic components. The improvement in the performance of 2.5 and 10 Gb/s intensity modulation, direct detection systems is assessed for receivers which utilize an analog taped delay line equalizer to compensate for signal distortion. Synchronous and fractionally spaced equalizers are evaluated. Smart receivers that jointly optimize the decision time, decision threshold, and equalizer tap weights under a minimum bit error ration criterion are considered. This yields the optimum system performance and allows consideration of both reduced distortion and enhanced noise arising from the signal processing. The effectiveness of the equalization is determined as a function of several important system parameters. Three-tap and five-tap synchronous equalizers yield virtually the same improvement in receiver sensitivity. Depending on the system, a five-tap fractionally spaced equalizer with half-bit-period tap spacing may or may not be significantly more effective than a three-tap synchronous equalizer     

Dynamic analysis of radiation and side-mode suppression in asecond-order DFB laser using time-domain large-signal traveling wavemodel

In this paper, we have developed a relatively simple algorithm to calculate the large-signal dynamic response of DFB lasers by solving the time-dependent coupled wave equations directly in the time domain. The spontaneous emission noise, longitudinal variations of carrier (hole burning) and photon densities as well as that of the refractive index are taken into consideration. To demonstrate the power of this straightforward algorithm, the model shows how the side-mode suppression ratio in devices with high κL and a λ/4: phase shift is significantly affected by the radiation in the second-order DFB laser. The time-dependent radiation pattern in grating-coupled surface-emitting lasers is also calculated for the first time     

Theory of enhanced amplitude modulation bandwidth in push-pullmodulated DFB lasers

Push-pull modulation of a two contact, uniform DFB laser enables amplitude modulation bandwidths well beyond the conventional electron-photon resonance limit for single contact devices. A small signal analytic theory for this AM response is given     

Aberrant responses of human lymphocytic neoplasms to cytokine regulation

Studies in this laboratory have recently focused on two hemic neoplasms: B cell chronic lymphocytic leukemia (B-CLL) and a T cell disorder, Sézary syndrome. These tumors do not have consistent cytogenetic or molecular genetic alterations, and so we have concentrated on their response to and production of various regulatory cytokines. Although B-CLL cells show variable proliferative responses when exposed to transforming growth factor beta (TGF beta), these cells have consistently shown resistance to the pro-apoptotic effects of this cytokine. Also, interleukin 4 (IL4), IL5, and interferon-gamma (IFN gamma) all show a consistently increased protective effect against apoptosis in B-CLL cells as compared to normal human B cells. Thus, a defect in apoptosis appears to be an important factor in the pathogenesis of CLL. By contrast, the neoplastic T cells of Sézary syndrome show a consistent resistance to the antiproliferative effects of TGF beta, suggesting that aberrant proliferation is more important than apoptosis in this disorder. In both neoplasms, we have shown that the defective responses to cytokines are in some instances related to alterations in receptor expression, but this has not been true in all circumstances, and other stages in the signaling pathways are being investigated. As we define more precisely the specific defects that contribute to the clonal expansion of these neoplasms, the findings may ultimately lead to improved clinical control of these disorders.     

Orientation effects on indexing of electron backscatter diffraction patterns

Automated Electron Backscatter Diffraction (EBSD) has become a well-accepted technique for characterizing the crystallographic orientation aspects of polycrystalline microstructures. At the advent of this technique, it was observed that patterns obtained from grains in certain crystallographic orientations were more difficult for the automated indexing algorithms to accurately identify than patterns from other orientations. The origin of this problem is often similarities between the EBSD pattern of the correct orientation and patterns from other orientations or phases. While practical solutions have been found and implemented, the identification of these problem orientations generally occurs only after running an automated scan, as problem orientations are often readily apparent in the resulting orientation maps. However, such an approach only finds those problem orientations that are present in the scan area. It would be advantageous to identify all regions of orientation space that may present problems for automated indexing prior to initiating an automated scan, and to minimize this space through the optimization of acquisition and indexing parameters. This work presents new methods for identifying regions in orientation space where the reliability of the automated indexing is suspect prior to performing a scan. This methodology is used to characterize the impact of various parameters on the indexing algorithm.     

Shock-Wave Consolidation of Nanostructured Bismuth Telluride Powders

Nanostructured thermoelectric powders can be produced using a variety of techniques. However, it is very challenging to build a bulk material from these nanopowders without losing the nanostructure. In the present work, nanostructured powders of the bismuth telluride alloy system are obtained in kilogram quantities via a gas atomization process. These powders are characterized using a variety of methods including scanning electron microscopy, transition electron microscopy, and x-ray diffraction analysis. Then the powders are consolidated into a dense bulk material using a shock-wave consolidation technique whereby a nanopowder-containing tube is surrounded by explosives and then detonated. The resulting shock wave causes rapid fusing of the powders without the melt and subsequent grain growth of other techniques. We describe the test setup and consolidation results.     

Grain Size and Texture of Cu<Subscript>2</Subscript>ZnSnS<Subscript>4</Subscript> Thin Films Synthesized by Cosputtering Binary Sulfides and Annealing: Effects of Processing Conditions and Sodium

We investigate the synthesis of kesterite Cu₂ZnSnS₄ (CZTS) polycrystalline thin films using cosputtering from binary sulfide targets followed by annealing in sulfur vapor at 500°C to 650°C. The films are the kesterite CZTS phase as indicated by x-ray diffraction, Raman scattering, and optical absorption measurements. The films exhibit (112) fiber texture and preferred low-angle and Σ3 grain boundary populations which have been demonstrated to reduce recombination in Cu(In,Ga)Se₂ and CdTe films. The grain growth kinetics are investigated as functions of temperature and the addition of Na. Significantly, lateral grain sizes above 1 μm are demonstrated for samples grown on Na-free glass, demonstrating the feasibility for CZTS growth on substrates other than soda lime glass.     

Five-Parameter Grain Boundary Inclination Recovery with EBSD and Interaction Volume Models

While electron backscatter diffraction (EBSD) patterns are often used to present two-dimensional information about a material microstructure, they are in fact a product of the three-dimensional electron interaction volume. Consequently, 3D spatial information exists in EBSD images, which is generally not accessed. Specifically, the inclination of the grain boundary plane may be observed in EBSD patterns taken near grain boundaries. If, at the same time, the shape of an electron interaction volume in the material is known, a grain boundary plane normal direction can be obtained from a sequence of EBSD images taken stepwise in a line crossing the grain boundary. Here, these two principles are used for demonstrating the determination of grain boundary normal vectors from EBSD images. Coherent twin boundaries and focused ion beam serial scan data are used for validation. Results indicate a mean error for this approach of 3 deg with a standard deviation of 3.8 deg.     

Hepatosplenic gammadelta T-cell lymphoma: ultrastructural, immunophenotypic, and functional evidence for cytotoxic T lymphocyte differentiation

Hepatosplenic gammadelta T cell lymphoma (TCL) is a rare, aggressive subset of peripheral TCL that presents with hepatosplenomegaly and cytopenias. Detailed clinicopathological, ultrastructural, and cytogenetic analyses of these lymphomas are limited; functional characteristics of these lymphomas are unknown. We have undertaken a clinicopathological, immunophenotypic, ultrastructural, cytogenetic, and functional analysis of three hepatosplenic gammadelta TCLs. All patients presented with massive hepatosplenomegaly and anemia, thrombocytopenia, or severe neutropenia; terminal blastlike transformation occurred in one patient. Combination chemotherapy had no response in two patients, but induced complete remission in one. gammadelta T cell receptor (TCR) expression and clonal TCRdelta gene rearrangements were documented in each case. Two different subsets of gammadelta TCL were identified based on delta chain variable region usage; two lymphomas were Vdelta1+, whereas the third was negative for both Vdelta1 and Vdelta2. Cytogenetic analysis was performed on two lymphomas; isochromosome 7q and probable trisomy 8 was shown in one of the Vdelta1+ lymphomas, whereas the Vdelta1 negative lymphoma had 14p+ with t(1;14)(q21;p13). NK cell-associated antigens (CD11c, CD16, or CD56) and cytotoxic T lymphocyte (CTL) effector proteins (perforin, granzyme B, TIA-1, and Fas ligand) were expressed by each lymphoma; dense core cytolytic granules were observed by electron microscopy in both lymphomas studied. Functional studies performed in two cases showed TCR-mediated cytolysis of P815 x 2 FcR+ cells induced by anti-CD3 in a redirected cytolysis assay in one of the CD56+, Vdelta1+ lymphomas, whereas IFNgamma secretion was induced by anti-CD3 in the CD56-, Vdelta1 negative lymphoma. These studies show that hepatosplenic gammadelta TCLs have CTL differentiation, retain functional activity in vitro, and are derived from at least two gammadelta T cell subsets.