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As part of an extensive cross-sectional survey of Norwegian physicians carried out in 1993 the 1,158 retired members of The Norwegian Medical Association were sent a questionnaire about their social situation, work activity, health and well-being. The response rate was 76%. 62% of the respondents were 75 years or older, and 13% were women. 44% were still active, doing clinical, research, or consultation work. The most prevalent complaint was lower back trouble, followed by arthrosis and hypertension. It was relatively common to prescribe one's own drugs. 6-8% of physicians under 75 years and 28% of those over 84 years needed practical help, but the great majority rated their life quality as good or excellent. 相似文献
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P. P. Poluektov S. S. Shirokov O. V. Kholopova M. A. Chernikov S. K. Savin E. V. Shirokova 《Radiochemistry》2014,56(3):308-310
A pulsed decontamination apparatus was developed and tested. Its operation is based on the action of oscillating liquid flow on contaminated objects. It ensures efficient decontamination of items and parts of complex geometry with deep contaminations and with contaminations blocked by corrosion products. 相似文献
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IaN Sho?khet OG Ogloblina EA Tse?makh TD Mal''chenko 《Canadian Metallurgical Quarterly》1994,66(3):64-67
Prevailing fibrin-formation in the pleural cavity entails hypoactivity of trypsin-like proteinases and a high inhibitory potential in the serum and pleural exudate. Streptokinase preparations appeared an effective means of pharmacological pulmonary decortication in patients with high pleural levels of plasminogen. The authors obtained higher efficacy of conservative therapy for pyothorax when they used a specially designed technique of intrapleural administration of streptokinase-activated fresh frozen plasma of the same group. The outcomes of the disease were also improved noticeably. 相似文献
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OG Gómez-Duarte B Lucas ZX Yan K Panthel R Haas TF Meyer 《Canadian Metallurgical Quarterly》1998,16(5):460-471
Helicobacter pylori is a Gram-negative bacterial pathogen associated with gastritis, peptic ulceration, and gastric carcinoma. The bacteria express a strong urease activity which is known to be essential for colonization of gnotobiotic pigs and nude mice. UreA and UreB, two structural subunits of the active enzyme, were expressed in the attenuated Salmonella typhimurium live vaccine SL3261 strain. Evaluation of protection against H. pylori was performed in Balb/c mice by oral immunization with a single dose of the vaccine strain. Five weeks after immunization, mice were challenged orally three times with a mouse-adapted H. pylori wild type strain and, six weeks later, mice were sacrificed to determine H. pylori infection by detection of urease activity from the antral region of the mouse stomachs. In several independent experiments, we observed 100% infection with H. pylori in the non-immunized mice and no infection (100% protection) in the mice immunized with S. typhimurium expressing recombinant UreA and UreB. Specific humoral and mucosal antibody responses against UreA and UreB were observed in mice immunized as indicated by western blots and ELISA assays. These data shows that oral immunization of mice with urease subunits delivered by an attenuated Salmonella strain induced a specific immune response and protected mice against H. pylori colonization. Single oral dose immunization with UreA and UreB delivered by a live Salmonella vaccine vector appears to be an attractive candidate for human vaccination against H. pylori infection. In addition, this model will aid to elucidate the effective protection mechanisms against H. pylori in the gastric mucosa. 相似文献
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