Genetic analysis of the South Altaian population of the Mendur-Sokkon village, Altai Republic

This study was a continuation of complex research on the gene pool of indigenous Siberian populations conducted at the Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences. In the population of South Altaians from the Mendur-Sokkon village, Ust'-Kanskii raion, Altai Republic, polymorphism for the following genetic markers was studied: blood groups ABO, MNSs, Rhesus, Kell, Duffy, and P; erythrocyte acid phosphatase (AcP); phosphoglucomutase 1 (PGM1); haptoglobin (Hp); and transferrin (Tf). The genetic position of South Altaians relative to the populations of the European part of Russia, Siberia, and the Urals was estimated. It was demonstrated that the gene pool of the South Altaian population of Mendur-Sokkon possessed both Caucasoid and Mongoloid genetic characteristics, with the latter prevailing. Genetically, this population is most closely related to Mongols and Nentsis. The genetic distance between South and North Altaians was large; this agreed with earlier genetic data and confirmed anthropological and ethnographic evidence indicating that these two groups had different backgrounds and were at different stages of ethnogenesis.     

Doctors who perform operations. A study on in-hospital surgery in four diverse geographic areas (second of two parts)

To facilitate manpower planning in the surgical field, a study was c onducted into the work loads of surgeons in various specialities in 4 different geographical areas. Surgeons in group practice and surgeons who were Board-certified specialists carried a statistically significant larger work load of surgery. The certified surgeons performed more and more complex operations. The mean operative work load increased steeply with age, reaching a maximum at 40-44 years, and fell linearly after that age. Approximately 18 years following medical school graduation were needed for a surgeon to achieve his maximum work load. The geographic factor had no appreciable effect on work loads. Tables which broke down frequencies for each major type of operation for each type of surgical specialist indicated that even commonplace operations were not frequent events on the average for any individual surgeon. It is concluded from the study that work loads are relatively low due to excessive supply of surgeons. This is of concern because there is some doubt about maintenance of surgical skills by those doctors who perform infrequent operations. The widest variation in practice was evident between ophthalmologists and thoracic surgeons, indicating that manpower planning in this field would have to be done on a specialty-by-specialty basis. 3 plans for redistributing the operative work load and reducing the number of specialist surgeons are considered.     

Seroepidemiologic investigations of human hepatitis caused by A, B, and a possible third virus

The results of magnet implantation in the upper and lower eyelids of 29 patients suffering from Keratopathia due to lagophthalmos due to facial palsy as well as the surgical techniques involved are described. Contrary to a lateral tarsorrhaphy - still popular today - this method does not alter the form or the size of the palpebral fissure nor does it hinder the visual field. It is technically simple to perform and easily reversible should nerve function recover. The subjective results were also good.     

Antibiotic activity of cultures of the species of the genus Actinomadura

Sixty five cultures of Actinomadura were isolated from samples of different soils. The study of their antibiotic activity on liquid nutrient media showed that 49 of them were active against gram-postive bacteria. The antibiotics isolated fromsome cultures of Am. carminata, Am. rubra, Am. coerulea and Am. luteofluorescens had antitumor effect in experiments on animals.     

Sine-Wave Signal Characterization Using Square-Wave and ΣΔ-Modulation: Application to Mixed-Signal BIST

This paper presents a method for extracting, in the digital domain, the main characteristic parameters of an analog sine-wave signal. It is based on a double-modulation, square-wave and sigma-delta, together with a simple Digital Processing Algorithm. It leads to an efficient and robust approach very suitable for BIST applications. In this line, some considerations for on-chip implementation are addressed together with simulation results that validate the feasibility of the proposed approach.Diego Vázquez was born in El Coronil, Sevilla, Spain, in 1966. He received the Licenciado en Física degree in 1989 and the Doctor en Ciencias Físicas degree in 1995, both from the University of Sevilla, Spain. Since 1990, he has been with the Departamento de Electrónica y Electromagnetismo, University of Sevilla, where he is a Associate Professor, and also with the Instituto de Microelectrónica de Sevilla, Centro Nacional de Microelectrónica (IMSE-CNM-CSIC), Sevilla, Spain. He has published about 100 papers in international journals, books and major conferences. In 1992 he won the Best Paper Award of the 10th IEEE VLSI Test Symposium. His research interests are in the fields of design, fault tolerance, test, and design for testability of analog and mixed-signal circuits.Gloria Huertas was born in Sevilla, Spain, in 1974. She received the Licenciado en Física degree in 1997 and the Ph.D. in 2004, both from the University of Sevilla, Spain. Since then, she has been with the Departamento de Electrónica y Electromagnetismo, University of Sevilla, where she is Assistant Professor, and also with the Instituto de Microelectrónica de Sevilla, Centro Nacional de Microelectrónica (IMSE-CNM-CSIC), Sevilla, Spain. Her research focuses on designing electronic mixed-signal circuits and systems including techniques for testability.África Luque was born in Zamora (Spain) in 1977. She received the Licenciado en Física degree in 2000 from the University of Sevilla, Sevilla, Spain. She is with the Departamento de Electrónica y Electromagnetismo, University of Sevilla, and also with the Instituto de Microelectrónica de Sevilla, Centro Nacional de Microelectrónica (IMSE-CNM-CSIC), Sevilla, Spain, where she is currently pursuing the Ph.D. degree. Her research focuses on the design and test of mixed-signal circuits including Silicon-On-Insulator technologies.Manuel J. Barragan was born in Sevilla, Spain, in 1980. He received the Licenciado en Física degree in 2003 from the University of Sevilla, Sevilla, Spain. He is currently pursuing the Ph.D. degree from the Instituto de Microelectrónica de Sevilla (IMSE, CNM) on the topics of test and design for testability of analog and mixed-signal circuits.Gildas Leger was born in St. Brieuc, Côtes dArmor, France, in 1976. He received the Ingénieur en Physique degree in 1999 from the National Institute of Applied Sciences (INSA) of Rennes, France.He is currently pursuing the Ph.D. degree from the Instituto de Microelectrónica de Sevilla (IMSE, CNM). His research focuses on designing electronic mixed-signal circuits and systems including techniques for testability, specially in the domain of analog to digital conversion.Adoración Rueda joined the Department of Electronics and Electromagnetism at the University of Seville in 1976 as Assistant Professor, and obtained the Ph.D. degree in 1982. From 1984 to 1996 she was Associate Professor in that Department, where now holds the position of Full Professor in Electronics. In 1989 she became researcher at the Department of Analog Design of the National Microelectronics Center (CNM), now Institute of Microelectronics at Seville (IMSE).She has participated in several research projects financed by the Spanish CICYT and by different programs of the European Community. She has published about 135 papers in international journals, books and major conferences. In 1992 she won the Best Paper Award of the 10th IEEE VLSI Test Symposium. Her research interests are currently focused on the topics of Design and Test of Analog and Mixed-signal Circuits, Behavioral Modeling of Mixed-signal Circuits, and development of CAD tools.Jose Luis Huertas received the Licenciado en Física degree nd the Doctor en Ciencias Físicas degrees in 1969 and 1973, respectively, both from the University of Sevilla, Spain.From 1970 to 1971, he was with the Philips International Institute, Eindhoven, The Netherlands, as a postgraduate student. Since 1971, he has been with the Departamento de Electrónica y Electromagnetismo, University of Sevilla, Spain, where he is a Full Professor. He is also the Director of the Instituto de Microelectrónica de Sevilla, Centro Nacional de Microelectrónica de Sevilla, Seville, Spain. His current interests include the design and testing of analog/digital integrated circuits, computer-aided IC analysis and design, fuzzy logic, nonlinear microelectronics, and neural networks.     

In vivo and in vitro studies of 15alpha-hydroxyprogesterone in the human placenta

Studies were conducted to determine the fate of 15alpha-hydroxyprogesterone in human placental tissue. Tritiated 15alpha-hydroxyprogesterone was perfused through normal human placentas in situ at the time of Cesarean section and incubated with a 10,000x g microsomal supernate of the placenta in vitro. In both systems the substrate, but no additional metabolites were identified. These findings indicate that 15alpha-hydroxyprogesterone is not metabolized during its passage in the human term placenta, and suggests that because of its fetal origin clinical measurements of 15alpha-hydroxyprogesterone may provide a valuable index to the status of fetal viability.