Dopamine and intestinal mucosal tissue oxygenation in a porcine model of haemorrhage

Haemorrhage is associated with intestinal mucosal hypoxia and impaired gut barrier function. Dopamine increases oxygen delivery to the intestinal mucosa and may thus counteract haemorrhage-induced mucosal hypoxia. Jejunal mucosal tissue oxygen tension (mucosal PO2) and jejunal oxygen saturation of mucosal microvascular haemoglobin (mucosal HbO2) were measured in 14 anaesthetized pigs. Seven animals served as controls (group C) and seven received continuous infusion of dopamine 16 micrograms kg-1 min-1 (group D) while 45% of blood volume was removed in three equal increments. Resuscitation was performed using shed blood and fluid. Mean arterial pressure and systemic oxygen delivery decreasing significantly during haemorrhage and returned to baseline after resuscitation in both groups. Mucosal PO2 decreased from 4.4 to 1.7 kPa after haemorrhage (P < 0.01) and further to 1.5 kPa after resuscitation (P < 0.01) in group C whereas group D showed an increase from 3.9 to 5.9 kPa after the start of the dopamine infusion (P < 0.05), but no significant difference from baseline after haemorrhage (2.3 kPa) (ns) or resuscitation (3.1 kPa) (ns). Mucosal HbO2 decreased from 52 to 32% after haemorrhage (P < 0.05) and increased to near baseline (37%) (ns) after resuscitation in group C whereas group D showed no significant changes from baseline (54%) throughout the experiment. Comparison between groups showed higher mucosal PO2 and HbO2 values for group D animals after the start of the dopamine infusion (P < 0.05 each), after the first two steps of haemorrhage (P < 0.01 each) and after resuscitation (P < 0.05 each). We conclude that i.v. dopamine 16 micrograms kg-1 min-1 improved tissue oxygenation of the small intestinal mucosa during moderate haemorrhage and subsequent resuscitation.     

rwg: An assessment of within-group interrater agreement.

F. L. Schmidt and J. E. Hunter (1989) critiqued the within-group interrater reliability statistic (rwg) described by L. R. James et al (1984). S. W. Kozlowski and K. Hattrup (1992) responded to the Schmidt and Hunter critique and argued that rwg is a suitable index of interrater agreement. This article focuses on the interpretation of rwg as a measure of agreement among judges' ratings of a single target. A new derivation of rwg is given that underscores this interpretation. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Surface losses in transmission lines

Two derivations of the loss parameter R, entirely from wave considerations in the presence of a metallic interface, are presented. R, which represents surface losses, occurs in transmission line equations for propagation of the voltage across the plates and of the current in the plates. Explanation of the surface losses involves some radiation of the interior fields into the metallic surfaces that absorb electromagnetic energy, and that ultimately convert it into ohmic losses (heat). Although the approach may restrict the derivation to a planar interface, i.e., to a parallel-plate transmission line, that restriction is not so essential that it cannot be softened     

Very low surface recombination velocities on p-type silicon wafers passivated with a dielectric with fixed negative charge

Surface recombination velocities as low as 10 cm/s have been obtained by treated atomic layer deposition (ALD) of Al₂O₃ layers on p-type CZ silicon wafers. Low surface recombination is achieved by means of field induced surface passivation due to a high density of negative charges stored at the interface. In comparison to a diffused back surface field, an external field source allows for higher band bending, that is, a better performance. While this process yields state of the art results, it is not suited for large-scale production. Preliminary results on an industrially viable, alternative process based on a pseudo-binary system containing Al₂O₃ are presented, too. With this process, surface recombination velocities of 500–1000 cm/s have been attained on mc-Si wafers.     

Internal drift effects on the diffusion of Ag in CdTe

Anomalous diffusion profiles of Ag in single crystalline CdTe were observed using the radiotracer ¹¹¹Ag. The diffusion anneals were performed at 800 K under Cd or Te vapor and in vacuum with low Ag concentrations. The measured Ag profiles directly reflect the distribution of the self-interstitials and vacancies of the Cd sublattice and are the result of chemical self-diffusion which describes the variation of the deviation from stoichiometry of the binary crystal as a function of depth and time. It turned out that the spread of the Ag dopant essentially is determined by the drift of the charged defects within the electric field caused by the distribution of the extrinsic and intrinsic defects.     

Development of a predictive model for polymer/solvent diffusion coefficient calculations

A new calculation procedure for free‐volume parameters is considered in this work by using viscosity prediction methods and the Levenberg‐Marquardt calculation scheme. All parameters used in the Vrentas–Duda free‐volume theory can be estimated from pure component properties. The prediction results are compared with experimental data for some polymer/solvent systems. The diffusion coefficient calculated by Vrentas–Duda theory can be used in the modeling of membrane separation processes. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008     

MC3D-3D continuum radiative transfer, Version 2

A revised and greatly improved version of the 3D continuum radiative transfer code MC3D is presented. It is based on the Monte Carlo method and solves the radiative transfer problem self-consistently. It is designed for the simulation of dust temperatures in arbitrary geometric configurations and the resulting observables: spectral energy distributions, wavelength-dependent images, and polarization maps. The main objective is the investigation of “dust-dominated” astrophysical systems such as young stellar objects surrounded by an optically thick circumstellar disk and an optically thin(ner) envelope, debris disks around more evolved stars, asymptotic giant branch stars, the dust component of the interstellar medium, and active galactic nuclei.     

Hand-assisted laparoscopic live donor nephrectomy

Selenium is essential for humans because it protects the heart against cardiomyopathy. It may also reduce ischaemic heart disease owing to its antioxidant activity. It is known that Indian migrants in a number of countries have high incidences of ischaemic heart disease. In this study, fasting plasma selenium concentrations of Sikh migrants in Sydney (Australia) were measured to investigate whether selenium concentration is reduced in this community. The mean concentration of selenium in plasma (91.8 +/- 15.0 ng ml-1, n = 196) was within the normal range. A significantly higher plasma selenium concentration was demonstrated in males than in females (p < 0.01). This was mainly due to the difference in mean selenium concentrations between genders in vegetarians because no significant difference was observed in non-vegetarian males versus females. The mean concentration of selenium in teetotal males was similar to those who consumed alcohol. Despite significant variations with gender and diet, the selenium concentrations were within the normal range. The results suggest that selenium status is adequate in the Sikh community even though vegetarian diet is common and alcohol use is condones in males.