An upside-down normal loss function-based method for quality improvement

Traditional measures of process quality do not offer much information on how much better or worse a process is when finding optimal settings of a given problem. The upside-down normal loss function (UDNLF) is a weighted loss function that provides a more reasonable risk assessment to the losses of being off-target in product engineering research. The UDNLF can be used in process design and optimization to accurately reflect and quantify the losses associated with the process in a way which minimizes the expected loss of the upside-down normal (UDN). The function has a scale parameter which can be adjusted by the practitioners to account for the actual percentage of materials failing to work at specification limits. In this article, the ‘target is best’ case is addressed to estimate the expected loss of UDN due to variation from target in the robust process design and response surface modelling context. An approach is proposed to find the control factor settings of a system by directly minimizing the expected loss. The procedure and its merits are illustrated through an example.     

Investigation of flow properties in natural streams using the entropy concept

This paper examines the discharge and velocity distributions in natural open channel flows using the entropy theory. Flow measurements were carried out at four different cross‐sections in central Turkey. The mean and maximum velocities at these stations exhibited a linear distribution and the entropy parameter was calculated to be M=1.31. Using this value, discharges for all flow conditions were calculated as a function of the measured maximum velocities (u_max). It was observed that the u_max/H and z_max/H ratios remained relatively constant when 0.2≤y/T≤0.8, especially for the wider channels. Using these constant values for each station, u_max and z_max could be determined solely as a function of the water depth H. Although the calculated velocities were higher than those measured at some verticals, the entropy‐based approach presents an attractive alternative to the traditional flow‐measurement techniques for the determination of flow properties because of its simplicity and quick application.     

Throughput and delay analysis of multi-channel wireless infrastructure networks

Wireless infrastructure networks (WINs) provide ubiquitous connectivity to mobile nodes in metro areas. The nodes in such backbone networks are often equipped with multiple transceivers to allow for concurrent transmissions in multiple orthogonal channels. In this study, we develop an analytical model for the estimation of the delay and throughput performance of wireless infrastructure networks employing slotted ALOHA channel access and slotted Carrier Sense Multiple Access with Collision Avoidance (CSMA/CA) over multiple channels. The analytical model, which takes into account the correlation due to multi-hop transmissions, approximates the performance observed through simulations accurately.     

EFFECT OF INITIAL MOISTURE CONTENT ON THE THIN LAYER DRYING CHARACTERISTICS OF HAZELNUTS DURING ROASTING

ABSTRACT

Effect of initial moisture content on the thin layer drying characteristics of hazelnuts during roasting was described for a temperature range of 100-160°C, using several thin layer equations. The effective diffusivity varied from 2.8×10^?7 to 21.5×10^?7m²/s over the temperature and moisture range. Temperature dependence of the diffusivity coefficient was described by Arrhenius-type relationship. The activation energy for moisture diffusion was found to be 2703 kJ/kg, 2289 kJ/kg and 2030 kJ/kg for the initial moisture content of 12.3% db, 6.14% db, and 2.41% db, respectively. Two-term equation gave better predictions than Henderson and Pabis and Thompson equations, and satisfactorily described thin layer drying characteristics of hazelnut roasting. A generalised mathematical model with the linear temperature dependence for moistured, non-treated and pre-dried hazelnuts were also developed.     

Production of the biomimetic small diameter blood vessels for cardiovascular tissue engineering

A novel biomimetic vascular graft scaffolds were produced by electrospinning method with the most superior characteristics to be a proper biomimetic small diameter blood vessel using Polycaprolactone(PCL), Ethyl Cellulose(EC) and Collagen Type-1 were used to create the most convenient synergy of a natural and synthetic polymer to achieve similarity to native small diameter blood vessels. Scanning Electron Microscopy(SEM), Fourier Transform Infrared Spectroscopy(FTIR), Differential Scanning Calorimetry Analysis(DSC), tensile measurement tests, and in-vitro and in-vivo applications were performed. Results indicated significant properties such as having 39.33?nm minimum, 104.98?nm average fiber diameter, 3.2?MPa young modulus and 135% relative cell viability.     

Fastest random walk on a path

In this paper, we consider two convex optimisation problems in order to maximise the mixing rate of a Markov chain on an undirected path. In the first formulation, the holding probabilities of vertices are identical and the transition probabilities from a vertex to its neighbours are equal, whereas the second formulation is the more general reversible Markov chain with the same degree proportional stationary distribution. We derive analytical results on the solutions of the optimisation problems and compare the spectra of the associated transition probability matrices.     

Modulation by Ozone Therapy of Oxidative Stress in Chemotherapy-Induced Peripheral Neuropathy: The Background for a Randomized Clinical Trial

(1) Background: Chemotherapy-induced peripheral neuropathy (CIPN) decreases the quality of life of patients and can lead to a dose reduction and/or the interruption of chemotherapy treatment, limiting its effectiveness. Potential pathophysiological mechanisms involved in the pathogenesis of CIPN include chronic oxidative stress and subsequent increase in free radicals and proinflammatory cytokines. Approaches for the treatment of CIPN are highly limited in their number and efficacy, although several antioxidant-based therapies have been tried. On the other hand, ozone therapy can induce an adaptive antioxidant and anti-inflammatory response, which could be potentially useful in the management of CIPN. (2) Methods: The aims of this works are: (a) to summarize the potential mechanisms that could induce CIPN by the most relevant drugs (platinum, taxanes, vinca alkaloids, and bortezomib), with particular focus on the role of oxidative stress; (b) to summarize the current situation of prophylactic and treatment approaches; (c) to describe the action mechanisms of ozone therapy to modify oxidative stress and inflammation with its potential repercussions for CIPN; (d) to describe related experimental and clinical reports with ozone therapy in chemo-induced neurologic symptoms and CIPN; and (e) to show the main details about an ongoing focused clinical trial. (3) Results: A wide background relating to the mechanisms of action and a small number of experimental and clinical reports suggest that ozone therapy could be useful to prevent or improve CIPN. (4) Conclusions: Currently, there are no clinically relevant approaches for the prevention and treatment of stablished CIPN. The potential role of ozone therapy in this syndrome merits further research. Randomized controlled trials are ongoing.     

Monotonic torsional resistance and fatigue resistance of novel SCOPE RS instruments

To evaluate monotonic torsional resistance and fatigue resistance of novel SCOPE RS instruments and to compare ROTATE, Hyflex CM, OneCurve, and ProTaper Next instruments as a counterpart. The instrument groups were as follows: SCOPE RS; ROTATE; HyflexCM; OneCurve; ProTaperNext. The cyclic fatigue resistance of unused instruments was tested at both room and body temperatures (n = 10). The time to fracture, the mean number of cycles until failure, and the length of the fractured fragments were analyzed. The monotonic torsional resistance of new instruments was measured in accordingly American National Standards/American Dental Association No. 28 and International Organization for Standardization 3630–1:2008 specifications (n = 10). The maximum torque and angular deflection at break were recorded. The fractographic examination was performed by scanning electron microscope. Energy‐dispersive X‐ray spectroscopy was used to investigate the microstructure of NiTi instruments. One‐way ANOVA with Games‐Howell Post Hoc multiple comparisons tests were used (p < .05). The ROTATE had superior cyclic fatigue resistance than other groups in both temperature conditions (p < .01). However, it exhibited lower torsional resistance than SCOPE RS (p < .01). SCOPE RS had superior torsional resistance than other groups (p < .01). Micrographs revealed typical features of fatigue behaviors in all groups. Weight percentages of the Ni and Ti revealed similarity for all instruments. The novel SCOPE RS instruments presented superior monotonic torsional resistance but failed to show any improvement in the cyclic fatigue resistance compared with its counterparts, ROTATE, HyflexCM, and OneCurve.     

Effects of particle size and sintering atmosphere on the structure and performance of 316L/SiC composite hollow fiber membranes

Journal of Porous Materials - 316L stainless steel hollow fiber membranes (HFs) are alternatives for polymer and ceramic based membranes. Chemical and waste treatment industries are application...