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排序方式: 共有123条查询结果,搜索用时 15 毫秒
71.
72.
Koşar A Şeşen M Oral O Itah Z Gozuacik D 《IEEE transactions on bio-medical engineering》2011,58(5):1337-1346
This paper presents a study that investigates the destructive energy output resulting from hydrodynamic bubbly cavitation in microchannels and its potential use in biomedical applications. The research performed in this study includes results from bubbly cavitation experiments and findings showing the destructive effects of bubbly cavitating flow on selected solid specimens and live cells. The bubbles generated by hydrodynamic cavitation are highly destructive at the surfaces of the target medium on which they are carefully focused. The resulting destructive energy output could be effectively used for biomedical treatments, such as destroying kidney stones (renal calculi) or killing cancer cells. Motivated by this potential, the cavitation damage to cancerous cells and material removal from chalk pieces (which possess similar material properties as some kidney stones) was investigated. Our results showed that cavitation could induce damage both on chalk pieces and leukemia/lymphoma cells. We discovered that hydrodynamic cavitation exposure had early and delayed effects on cancer cell survival. Hence, the potential of hydrodynamic bubbly cavitation generated at the microscale for biomedical treatments was revealed using the microchannel configuration as a microorifice (with an inner diameter of 147 μm and a length of 1.52 cm), which acts as the source of bubbly cavitating flows. 相似文献
73.
The goal of this study was to create wear resistant ultra high molecular weight polyethylene (UHMWPE) with improved strength and toughness. It was previously demonstrated that high temperature melting (HTM) of UHMWPE at 280-320 °C improved its toughness without detrimentally affecting its wear resistance. We hypothesized that radiation cross-linking after high temperature melting could further improve the wear resistance of UHMWPE, and the loss in toughness by radiation cross-linking could be compensated by the improved toughness achieved by the high temperature melting prior to irradiation. In this work, we demonstrated that irradiation after HTM generated UHMWPE with improved toughness compared to the irradiated UHMWPEs without HTM, partly due to the low cross-link density of irradiated HTM UHMWPE. At a given cross-link density, irradiated HTM UHMWPEs showed higher wear resistance than irradiated UHMWPE. Therefore, successive HTM and radiation cross-linking strategy is promising to create UHMWPE materials with low wear and improved mechanical properties for total joint implants. 相似文献
74.
In a previous communication we showed improvement in the wear resistance and toughness of cross-linked ultrahigh molecular weight polyethylene (UHMWPE) for total joint implants by radiation cross-linking after high temperature melting (HTM). In this study, we hypothesized that introduction of vitamin E into UHMWPE before high temperature melting could improve the oxidative stability of these UHMWPEs with low wear and high toughness. Vitamin E was blended with UHMWPE powder at concentrations of 0.1 and 0.2 wt% and consolidated, followed by melting at 300 and 320 °C for 5 h, and subsequent irradiation with electron beam to 150 kGy. These vitamin E/UHMWPE blends showed improved tensile and impact toughness and good wear resistance in comparison with the radiation cross-linked vitamin E/UHMWPE blends. Aggressive accelerated aging with or without pro-oxidant lipids showed that vitamin E-blended, high temperature melted and subsequently irradiated UHMWPE had good oxidation resistance. 相似文献
75.
Various economical crises have affected Turkish economy during the last decade and construction industry has always been among the hardest hit; giving the idea that a comprehensive approach to crisis management is unavoidable. However, literature showed no findings related with crisis management applications by construction companies. Thus, a questionnaire survey was undertaken by the top management of 120 construction companies to investigate the degree of crisis management applications throughout the industry, mainly focusing on the outcomes during the economical crisis in 2001. Frequency analysis, Likert scale of comparison, Thurstone's paired comparisons, Pearson's chi-square test and Fisher's exact test were used to evaluate the results. 相似文献
76.
SR Kapadia H Oral J Lee M Nakano GE Taffet DL Mann 《Canadian Metallurgical Quarterly》1997,81(2):187-195
During the metastatic cascade, a tumor cell passes through several connective tissue barriers which consist of various adhesive molecules, such as fibronectin, laminin, collagens, and other glucoproteins and proteoglycans. Tumor invasion is a complex process involving cell adhesion, motility (migration), and the degradation of tissue barriers caused by the different proteases secreted by tumor cells. Therefore, understanding the invasion mechanism and the control mechanisms of the invasive properties of tumor cells may help in the development of anti-metastatic and anti-invasive therapies. We here focused our attention on the functional molecules involved in the invasive process as targets to control tumor metastasis, and screened the inhibitors of tumor invasion into basement membranes. 相似文献
77.
Imran Oral 《应用聚合物科学杂志》2015,132(45)
This study presents the ultrasonic characterization of conductive epoxy resin (ER)/polyaniline (PANI) composites. The prepared PANI is mixed with ER matrix at weight percentages of 5%, 10%, and 15% for preparing the ER/PANI composites. The effects of PANI amount on the mechanical properties of ER/PANI composites are investigated by ultrasonic pulse‐echo‐overlap method. Also, electrical conductivity, ultrasonic wave velocity and ultrasonic micro‐hardness values of ER/PANI composites are correlated. Experimental results show that there is an excellent correlation between ultrasonic micro‐hardness and ultrasonic shear wave velocity. Also, the results of ultrasonic velocities and elastic constants values illustrate that the appropriate combination ratio is 95 : 5 for ER and PANI in ER/PANI composites. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015 , 132, 42748. 相似文献
78.
79.
Dielectric behavior induced by vitamin E and electron beam irradiation in ultra high molecular weight polyethylene
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Jose Antonio Puértolas Maria Jose Martínez‐Morlanes Roberto Teruel Alfonso Martinez‐Felipe Ebru Oral Francisco Javier Pascual Amparo Ribes 《应用聚合物科学杂志》2014,131(19)
Radiation cross‐linked ultra high molecular weight polyethylenes (UHMWPEs) have been successfully used as wear resistant bearing surfaces in total joint arthroplasty. A recent development in this field is the incorporation of the antioxidant vitamin E into radiation cross‐linked UHMWPE. This study investigates the effects of radiation cross‐linking and vitamin E incorporation on the dielectric behavior of UHMWPE. The dielectric relaxations of virgin and 0.1 wt % vitamin E‐blended UHMWPE and their irradiated counterparts (up to 300 kGy dose) were investigated. To determine the effect of vitamin E content alone, vitamin E‐loaded UHMWPEs were used. The results showed that radiation cross‐linking and vitamin E content both increased dielectric polarization in UHMWPE and under some conditions induced electrical conductivity. This result is significant because it shows that the conductive response of UHMWPE‐bearing surfaces may depend on manufacturing processes and additives. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014 , 131, 40844. 相似文献
80.
Imran Oral 《Polymer Composites》2015,36(3):584-590
Non‐destructive techniques are suitable alternatives for characterization of composites. The aim of this study is to analyze the composites of epoxy resin (ER)/marble waste powder (MWP) by ultrasonic method. The effects of marble powder, coagulant type, and dosage on the ultrasonic properties of ER/MWP composites were investigated. The ultrasonic wave velocities of composites were measured with the pulse–echo method at room temperature by a flaw detector. The values of the acoustic impedance, Poisson's ratio, and elastic constants of the samples were calculated by the measured values of the densities and both longitudinal and shear ultrasonic wave velocities. According to the results, the ER/MWP composite using sepiolite coagulant in dosages of 4 g/500 mL has showed the highest values of elastic constants. POLYM. COMPOS. 36:584–590, 2015. © 2014 Society of Plastics Engineers 相似文献