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排序方式: 共有7025条查询结果,搜索用时 234 毫秒
61.
J Barrette R Bellwied P Braun-Munzinger WE Cleland T Cormier G Dadusc G David J Dee O Dietzsch M Fatyga SV Greene JV Germani JR Hall TK Hemmick N Herrmann RW Hogue B Hong K Jayananda D Kraus BS Kumar R Lacasse D Lissauer WJ Llope TW Ludlam R Majka SK Mark JT Mitchell M Muthuswamy E O'Brien C Pruneau FS Rotondo da Silva NC J Simon-Gillo U Sonnadara J Stachel H Takai EM Takagui TG Throwe L Waters C Winter D Wolfe CL Woody N Xu Y Zhang Z Zhang C Zou 《Canadian Metallurgical Quarterly》1995,52(5):2679-2683
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Data from the Cancer Registry of Slovenia were used in a cohort study to determine whether the incidence of second primary cancers in patients with first primary breast cancer differs from the incidence expected in the general population. Special interest was given to long-term survivors. The expected numbers of second primary cancers were calculated by multiplying the number of appropriate person-years at risk by the corresponding age- and calendar-period-specific cancer incidence rates for women in Slovenia. The risk of a second primary cancer was expressed as the standardized incidence ratio (SIR). Of the 8,917 patients newly diagnosed in the period 1961-85 and followed-up to the end of 1994, 547 (6.2 percent) developed second primary cancers, whereas 410 (4.7 percent) were expected (SIR = 1.3, 95 percent confidence interval [CI] = 1.2-1.4). The risk was higher among younger patients. In long-term survivors, the risk was increased significantly for second primary cancer of the breast (SIR = 1.4, CI = 1.1-1.7), lung cancer (SIR = 1.6, CI = 1.1-2.3), melanoma (SIR = 2.7, CI = 1.5-4.4) and non-melanoma skin cancers(SIR = 2.0, CI = 1.6-2.4), corpus uteri cancer(SIR = 1.6, CI = 1.2-2.1), ovarian cancer(SIR = 2.3, CI = 1.7-3.0), and thyroid cancer (SIR = 2.5, CI = 1.2-4.6). Our results confirm the findings of several cohort studies carried out in Europe, the United States, and Japan, indicating that breast cancer patients should be monitored carefully for the occurrence of second primary cancers. 相似文献
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Optimal Locations of Groundwater Extractions in Coastal Aquifers 总被引:1,自引:0,他引:1
A regional water supply management model for coastal aquifers was developed. One of its outcomes is the definition of the
optimized locations for groundwater withdrawal. Such a tool permits the analysis of alternative plans for groundwater extraction
and the sustainable use of water resources in a coastal aquifer subject to saltwater intrusion. The principal components are
the evolutionary optimization and the analytical/numerical simulation models. The optimization technique looks for the best
well locations taking into consideration the economic results and the satisfaction of the societal water demand. However these
two concerns are conditioned by trying to control the saltwater intrusion, i.e., preserving the environmental equilibrium.
The simulation model uses the governing mathematical equations for groundwater movement to find the interface between freshwater
and saltwater. Because of the non-linearity in the system and the possibility of a jumping interface, a security distance
was defined. This is a controlling variable which can be set by the decision makers. The model was applied to a typical case
with interesting results. For example, diagrams showing the relationship between the location of the wells and the security
distance(s) are of importance to the managers. It was also crucial to have an understanding of the tradeoffs between groundwater
withdrawals, positions of the wells from the coast line, and the security distance. The model was also applied to a real case
in order to relate the extractions, distances and artificial recharge (not presented in this paper). 相似文献
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