An Overview and Future Perspectives of Aluminum Batteries

A critical overview of the latest developments in the aluminum battery technologies is reported. The substitution of lithium with alternative metal anodes characterized by lower cost and higher abundance is nowadays one of the most widely explored paths to reduce the cost of electrochemical storage systems and enable long‐term sustainability. Aluminum based secondary batteries could be a viable alternative to the present Li‐ion technology because of their high volumetric capacity (8040 mAh cm^?3 for Al vs 2046 mAh cm^?3 for Li). Additionally, the low cost aluminum makes these batteries appealing for large‐scale electrical energy storage. Here, we describe the evolution of the various aluminum systems, starting from those based on aqueous electrolytes to, in more details, those based on non‐aqueous electrolytes. Particular attention has been dedicated to the latest development of electrolytic media characterized by low reactivity towards other cell components. The attention is then focused on electrode materials enabling the reversible aluminum intercalation‐deintercalation process. Finally, we touch on the topic of high‐capacity aluminum‐sulfur batteries, attempting to forecast their chances to reach the status of practical energy storage systems.     

Assessing patients'' priorities and perceptions of the quality of health care: the development of the QUOTE-Rheumatic-Patients instrument

BACKGROUND: Stress can exacerbate a number of psychiatric disorders, many of which are associated with prefrontal cortical (PFC) cognitive deficits. Biochemical studies demonstrate that mild stress preferentially increases dopamine turnover in the PFC. Our study examined the effects of acute, mild stress exposure on higher cognitive function in monkeys and the role of dopaminergic mechanisms in the stress response. METHODS: The effects of loud (105-dB) noise stress were examined on a spatial working memory task (delayed response) dependent on the PFC, and on a reference memory task with similar motor and motivational demands (visual pattern discrimination) dependent on the inferior temporal cortex. The role of dopamine mechanisms was tested by challenging the stress response with agents that decrease dopamine receptor stimulation. RESULTS: Exposure to noise stress significantly impaired delayed-response performance. Stress did not impair performance on "0-second" delay control trials and did not alter visual pattern discrimination performance, which is consistent with impaired PFC cognitive function rather than nonspecific changes in performance. Stress-induced deficits in delayed-response performance were ameliorated by pretreatment with drugs that block dopamine receptors (haloperidol, SCH 23390) or reduce stress-induced PFC dopamine turnover in rodents (clonidine, naloxone hydrochloride). CONCLUSIONS: These results indicate that stress impairs PFC cognitive function through a hyperdopaminergic mechanism. Stress may take the PFC "off-line" to allow more habitual responses mediated by posterior cortical and subcortical structures to regulate behavior. This mechanism may have survival value, but may often be maladaptive in human society, contributing to the vulnerability of the PFC in many neuropsychiatric disorders.     

Optimal display conditions for quantitative analysis of stereoscopic cerebral angiograms

For several years the authors have been using a stereoscopic display as a tool in the planning of stereotactic neurosurgical techniques. This PC-based workstation allows the surgeon to interact with and view vascular images in three dimensions, as well as to perform quantitative analysis of the three-dimensional (3-D) space. Some of the perceptual issues relevant to the presentation of medical images on this stereoscopic display were addressed in five experiments. The authors show that a number of parameters-namely the shape, color, and depth cue, associated with a cursor-as well as the image filtering and observer position, have a role in improving the observer's perception of a 3-D image and his ability to localize points within the stereoscopically presented 3-D image. However, an analysis of the results indicates that while varying these parameters can lead to an effect on the performance of individual observers, the effects are not consistent across observers, and the mean accuracy remains relatively constant under the different experimental conditions.     

The role of topology in engineering design research

Aspects of the mathematical specialty of topology appear within several seemingly distinct areas of engineering design and engineering design theory. Indeed, the expression topology of a design is often used informally. In this article a primary intent is to demonstrate the diversity of applications of topology within engineering design. A complementary goal is to introduce the engineering design community to topology as a rich, formal, well-established mathematical discipline that may be of value for wider study. Upon reviewing some of these topological applications, it appears that topology holds promise as a basis for formalizing engineering design theory. This article considers topology as a basis for unifying design abstractions. The potential benefit may be the realization of commonalities between design aspects previously considered separately, where each now has its own attendant specialized, expensive analyses.     

Evaluation of artery visualizations for heart disease diagnosis

Heart disease is the number one killer in the United States, and finding indicators of the disease at an early stage is critical for treatment and prevention. In this paper we evaluate visualization techniques that enable the diagnosis of coronary artery disease. A key physical quantity of medical interest is endothelial shear stress (ESS). Low ESS has been associated with sites of lesion formation and rapid progression of disease in the coronary arteries. Having effective visualizations of a patient's ESS data is vital for the quick and thorough non-invasive evaluation by a cardiologist. We present a task taxonomy for hemodynamics based on a formative user study with domain experts. Based on the results of this study we developed HemoVis, an interactive visualization application for heart disease diagnosis that uses a novel 2D tree diagram representation of coronary artery trees. We present the results of a formal quantitative user study with domain experts that evaluates the effect of 2D versus 3D artery representations and of color maps on identifying regions of low ESS. We show statistically significant results demonstrating that our 2D visualizations are more accurate and efficient than 3D representations, and that a perceptually appropriate color map leads to fewer diagnostic mistakes than a rainbow color map.     

An investigation of student practices in asynchronous computer conferencing courses

This study investigated the online practices of students enrolled in graduate-level distance education courses. Using interviews and a questionnaire as data sources, the study sought to: (a) identify common practices that students adopt in asynchronous discussions, and (b) gain an understanding of why students adopt them. An analysis of the data suggests that many of the practices are coping mechanisms developed to help students more easily meet course participation requirements. Some of these are time saving strategies designed to reduce information overload (e.g., skimming messages rather than reading them carefully). Other strategies are designed to help students project an image of themselves as knowledgeable and collaborative course participants. It is argued that although these practices provide students with a level of efficiency in terms of meeting course requirements, they may inadvertently undermine learning.     

Adjustable speed surface subdivision

We introduce a non-uniform subdivision algorithm that partitions the neighborhood of an extraordinary point in the ratio σ:1−σ, where σ(0,1). We call σ the speed of the non-uniform subdivision and verify C¹ continuity of the limit surface. For σ=1/2, the Catmull–Clark limit surface is recovered. Other speeds are useful to vary the relative width of the polynomial spline rings generated from extraordinary nodes.     

Rapid scalar value classification and volume clipping for?interactive 3D medical image visualization

In many clinical scenarios, medical data visualization and interaction are important to physicians for exploring inner anatomical structures and extracting meaningful diagnostic information. Real-time high-quality volume rendering, artifact-free clipping, and rapid scalar value classification are important techniques employed in this process. Unfortunately, in practice, it is still difficult to achieve an optimal balance. In this paper, we present some strategies to address this issue, which are based on the calculation of segment-based post color attenuation and dynamic ray–plane intersection (RPI) respectively. When implemented within our visualization system, the new classification algorithm can deliver real-time performance while avoiding the “color over-accumulation” artifacts suffered by the commonly used acceleration algorithms that employ pre-integrated classification. Our new strategy can achieve an optimized balance between image quality and classification speed. Next, the RPI algorithm is used with opacity adjustment technique to effectively remove the “striping” artifacts on the clipping plane caused by the nonuniform integration length. Furthermore, we present techniques for multiple transfer function (TF) based anatomical feature enhancement and “keyhole” based endoscopic inner structure view. Finally, the algorithms are evaluated subjectively by radiologists and quantitatively compared using image power spectrum analysis.     

On the Use of Enumeration for Investigating the Performance of Hypothesis Tests for Economic Models with a Discrete Response Variable

This article notes that it is now practical to use the method of enumerationto analyse the performance of estimators and hypothesis tests of fullyparametric binary data models. The general method is presented and thenemployed to investigate the power performance of a common misspecificationtest for the Probit model. The advantages, disadvantages and limitations ofenumeration compared with standard Monte Carlo simulation are thendiscussed. Finally, an example from experimental economics is used todemonstrate that the methodology can also be used in small empirical studies.