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991.
B-scan ultrasonography was used to evaluate advance glaucomatous cupping of the optic disk (0.7 cup/disk ratio or greater) in one normal subject and six patients with glaucoma. The normal eye emitted a continuous echo from the posterior pole, which conformed to its mild degree of concavity. The glaucomatous eyes emitted echos from the posterior pole, demonstrating the more extreme concavity of the optic cup. Ultrasonographic evaluation of an acrylic plate containing holes of known diameter demonstrated the limits of resolution and artifacts that resulted from this examination. 相似文献
992.
Medical technology has improved remarkably over the past few generations, becoming more sophisticated and less invasive as the years progress. Until recently, however, completely noncontact health monitors have existed only in the realm of science fiction alongside flying cars and other promised technological marvels. Perhaps the best known example is the medical tricorder, used to collect medical information in the popular science fiction television series Star Trek. Now, with microwave Doppler radar phase modulation, noncontact respiration and heartbeat monitoring offers an attractive alternative to commonly prescribed cheststrap monitors. 相似文献
993.
We present further results from a study of Al/Au bilayer thermometers constructed for third sound detection. Here we report the transition temperature of such thermometers as a function of the Al/Au thickness ratio. We also report on the reproducibility of fabrication. 相似文献
994.
Online dating is unique in the pursuit of romance. The bond created between potential partners takes a different path than normal dating relationships. Online dating usually begins with a flurry of e-mail messages, each more intimate than the last. Traditional dating relationships that might take months to develop in the real world, take weeks or even days online. Much has been written about cyber-dating, but little research has been done. This series of four studies examines the online dating process, similarities and differences between online and traditional dating, and the impact of emotionality and self-disclosure on first (e-mail) impressions of a potential partner. Results indicate that the amount of emotionality and self-disclosure affected a person’s perception of a potential partner. An e-mail with strong emotional words (e.g., excited, wonderful) led to more positive impressions than an e-mail with fewer strong emotional words (e.g., happy, fine) and resulted in nearly three out of four subjects selecting the e-mailer with strong emotional words for the fictitious dater of the opposite sex. Results for self-disclosure e-mails were complex, but indicate that levels of self-disclosure led to different impressions. Low levels of self-disclosure were generally preferred in choosing for the fictitious dater, although these preferences differed by gender, education, and ethnic background. Results were discussed in terms of theories of computer-mediated communication. 相似文献
995.
Tongzhong Ju Yingchun Wang Rajindra P. Aryal Sylvain D. Lehoux Xiaokun Ding Matthew R. Kudelka Christopher Cutler Junwei Zeng Jianmei Wang Xiaodong Sun Jamie Heimburg-Molinaro David F. Smith Richard D. Cummings 《Proteomics. Clinical applications》2013,7(9-10):618-631
In many different human disorders, the cellular glycome is altered. An interesting but poorly understood alteration occurs in the mucin-type O-glycome, in which there is aberrant expression of the truncated O-glycans Tn (GalNAcα1-Ser/Thr) and its sialylated version sialyl-Tn (STn) (Neu5Acα2,6GalNAcα1-Ser/Thr). Both Tn and STn are tumor-associated carbohydrate antigens and tumor biomarkers, since they are not expressed normally and appear early in tumorigenesis. Moreover, their expression is strongly associated with poor prognosis and tumor metastasis. The Tn and STn antigens are also expressed in other human diseases and disorders, such as Tn syndrome and IgA nephropathy. The major pathological mechanism for expression of the Tn and STn antigens is compromised T-synthase activity, resulting from alteration of the X-linked gene that encodes for Cosmc, a molecular chaperone specifically required for the correct folding of T-synthase to form active enzyme. This review will summarize our current understanding of the Tn and STn antigens in terms of their biochemistry and role in pathology. 相似文献
996.
Brandon Paulson Danielle Cummings Tracy Hammond 《International journal of human-computer studies》2011,69(1-2):19-29
Activity recognition plays a key role in providing information for context-aware applications. When attempting to model activities, some researchers have looked towards Activity Theory, which theorizes that activities have objectives and are accomplished through interactions with tools and objects. The goal of this paper is to determine if hand posture can be used as a cue to determine the types of interactions a user has with objects in a desk/office environment. Furthermore, we wish to determine if hand posture is user-independent across all users when interacting with the same objects in a natural manner. Our experiments indicate that (a) hand posture can be used to determine object interaction, with accuracy rates around 97%, and (b) hand posture is dependent upon the individual user when users are allowed to interact with objects as they would naturally. 相似文献
997.
Ciprian Docan Fan Zhang Tong Jin Hoang Bui Qian Sun Julian Cummings Norbert Podhorszki Scott Klasky Manish Parashar 《Concurrency and Computation》2015,27(14):3724-3745
Managing the large volumes of data produced by emerging scientific and engineering simulations running on leadership‐class resources has become a critical challenge. The data have to be extracted off the computing nodes and transported to consumer nodes so that it can be processed, analyzed, visualized, archived, and so on. Several recent research efforts have addressed data‐related challenges at different levels. One attractive approach is to offload expensive input/output operations to a smaller set of dedicated computing nodes known as a staging area. However, even using this approach, the data still have to be moved from the staging area to consumer nodes for processing, which continues to be a bottleneck. In this paper, we investigate an alternate approach, namely moving the data‐processing code to the staging area instead of moving the data to the data‐processing code. Specifically, we describe the ActiveSpaces framework, which provides (1) programming support for defining the data‐processing routines to be downloaded to the staging area and (2) runtime mechanisms for transporting codes associated with these routines to the staging area, executing the routines on the nodes that are part of the staging area, and returning the results. We also present an experimental performance evaluation of ActiveSpaces using applications running on the Cray XT5 at Oak Ridge National Laboratory. Finally, we use a coupled fusion application workflow to explore the trade‐offs between transporting data and transporting the code required for data processing during coupling, and we characterize sweet spots for each option. Copyright © 2014 John Wiley & Sons, Ltd. 相似文献
998.
Jordan Frith Matt Morain Chris Cummings David Berube 《The Journal of communication》2011,61(1):E9-E12
999.
ABSTRACT: Five-carbon sugars affect cooked meat flavor by the Maillard reaction. This research extends to the effects of pH and cooking temperature on meaty and species flavor, sweetness, barnyard, and rancid flavor in sheepmeat. Glucose and xylose were each blended into ground longissimus meat to 0%, 0.5%, or 1% and heated to 75 °C. Xylose treatments browned more than glucose treatments, and xylose flavor effects were more marked. With xylose, sheepmeat flavor declined significantly, but meaty flavor also declined. Differences were marked between pH 5.93 and 6.52, but pH effects at lower pHs were more subtle. Sweetness increased in many treatments, suggesting that 75 °C did not fully exploit the Maillard reaction. Therefore, pressure-cooked casserole treatments, chilled and frozen, were used to study the effects of xylose, packaging, and storage time on flavor. There were no flavor differences due to chill packaging (foil laminate compared with barrier bag) (not significant). Xylose addition reduced sheepmeat flavor by 24% on the 1 to 9 intensity scale ( P < 0.001), while meaty flavor and sweetness were unaffected. Rancid flavor was reduced by xylose addition ( P < 0.01), and the reduction in barnyard flavor approached significance ( P = 0.07). Chilled storage time to 29 d did not affect any attribute. In the frozen casserole trial (stored exposed to air), xylose had no significant flavor effects (all P ≥ 0.38). However, storage to 71 d increased the rancid flavor score from a negligible 0.06 to 0.60 ( P = 0.04), suggesting that rancidity development swamped more subtle effects. 相似文献
1000.