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61.
Electromigration reliability of interconnect under bidirectional current stress has been studied in a wide frequency range (mHz to 200 MHz). Experimental results show that the AC lifetime rises with the stress current frequency. The current density exponent and the activation energy of AC lifetime are found to be twice that of DC lifetime. Pure AC current stress failure at extremely high current density is believed to result from thermal migration of metal at hot/cold transition points 相似文献
62.
When melting processes are associated with an exothermic heat of mixing, unique coupled transport phenomena take place. In
this article, a mathematical model has been developed to simulate these unique coupled heat and mass transfer events. The
model was based on the control-volume finite difference approach and on an enthalpy method. In order to verify the mathematical
model, a low-temperature physical model was established consisting of ice and sulfuric acid solutions. In this physical model,
both temperature and velocity measurements were carried out. The model predictions were compared with experimental measurements,
and they were found to be in good agreement. The model was also applied to a high-temperature system, namely, the melting
of silicon metal in liquid high carbon iron. The predictions distinguished two periods present in the entire melting process.
In the first period, the silicon was heated up. The second period, i.e., free melting period, occurred in tandem with the exothermic reaction, and consequently, the melting process was greatly
accelerated. As was the case with the low-temperature physical model, as with the high-temperature system, good agreement
was obtained between the predicted results and the experimental measurements. 相似文献
63.
The present study was conducted to evaluate the effects of caffeine and the benzodiazepine agonist diazepam, and a combination of both on beta-endorphin (beta-EN) levels in specific rat brain regions. Male Sprague-Dawley rats (150-200 g) adapted to a 12-hour light: 12-hour dark illumination cycle were used in this study. Caffeine (10 mg/kg), diazepam (2 mg/kg) or a combination of caffeine (10 mg/kg) and diazepam (2 mg/kg) were administered intraperitoneally to rats at 11:00 hr. Control animals were injected with saline. Animals were sacrificed by decapitation 1 h after injection, the brains were immediately removed; the cortex, hippocampus, hypothalamus and midbrain were dissected and their B-EN levels measured by radioimmunoassay. Caffeine administration significantly increased B-EN levels in the cortex. Similarly, administration of diazepam alone resulted in a significant increase of B-EN levels in cortex. However, concurrent administration of diazepam and caffeine resulted in higher increase of B-EN levels in cortex. No significant changes in B-EN levels were detected in hippocampus and midbrain after administration of either caffeine or diazepam alone. On the other hand, when diazepam and caffeine were concurrently administered a significant increase of B-EN levels were observed in the midbrain. Moreover, administration of diazepam alone resulted in a significant increase of B-EN levels in hypothalamus. This increase was still observed following concurrent administration of diazepam and caffeine. These results clearly indicate that diazepam alters caffeine-induced effects on B-EN in specific rat brain regions. 相似文献
64.
LJ Jones RH Upson RP Haugland N Panchuk-Voloshina M Zhou RP Haugland 《Canadian Metallurgical Quarterly》1997,251(2):144-152
We have prepared casein conjugates of two BODIPY dyes for use as fluorogenic protease substrates in homogeneous assays. Both conjugates are labeled to such an extent that the dyes are efficiently quenched in the protein, yielding virtually nonfluorescent substrate molecules. These fluorogenic substrates release highly fluorescent BODIPY dye-labeled peptides upon protease digestion, with fluorescence increases proportional to enzyme activity. These quenched substrates are suitable for the continuous assay of enzymatic activity using standard fluorometers, filter fluorometers, or fluorescence microplate readers using either fluorescein excitation and emission wavelengths to measure BODIPY FL casein hydrolysis or Texas Red wavelengths to detect proteolysis of BODIPY TR-X casein. Most current techniques for detecting protease activity, such as the fluorescein thiocarbamoyl casein (FTC-casein) protease assay, require extensive manipulation, including separation steps, and are therefore labor intensive and error-prone. In comparison, we found the BODIPY dye-labeled casein protease assays to be simple and precise and to have greater sensitivity and a broader dynamic range of detection than the FTC-casein assay. We were able to sensitively detect the activities of a wide variety of enzymes with these new substrates, including serine, acid, sulfhydryl, and metalloproteases. We also found the assay suitable for quantitating protease inhibitor concentrations and for real-time analysis of proteolysis. 相似文献
65.
获得了一种研究碲镉汞深能级的方法。通过分析迁移率 载子浓度与温度的关系,可以得到关于深能级的重要依据。 相似文献
66.
J Müller-Ehmsen K Brixius C Schulze RH Schwinger 《Canadian Metallurgical Quarterly》1997,355(6):727-732
Insect cell lines in culture are used for a variety of studies. In this laboratory imaginal disc cell lines have been established from primary cultures from third instar larvae, and used for a number of experiments. The effect of ageing on the morphology and physiology of Drosophila cell lines has received very little attention, although problems of genotypic or phenotypic changes in cell lines with age are recognized in other areas of animal cell culture. We tested our cell line Cl8+ for any difference in growth, morphology and response to 20-hydroxyecdysone (20HE) at different ages (passage numbers). The cells were found to multiply faster, adhere less firmly to the substrate and to lose the tendency to aggregate at higher passages. The response to 20HE in terms of cell numbers and induction of beta-galactosidase was similar at all passage numbers but morphological changes in hormone-treated cells were less obvious in the higher passages. Cell lines are likely to vary in the extent of ageing effects but workers are advised to be aware of the possibilities. We suggest the effects of age on cell lines should be established, and passage numbers noted in experimental reports. 相似文献
67.
68.
中国的三种非同步轨道卫星移动通信系统星座方案 总被引:6,自引:1,他引:5
本文介绍基于我国的三种非同步轨道卫星移动通信系统星座方案:低、中轨系统各有24和18颗星,轨道高度分别为1326和8035km,两系统各以5°和30°的仰角对我国的覆盖率为99.78%和99.96%;椭圆轨道系统12颗星,近、远地点分别为427和2906km,以7°和15°仰角对我国北纬20°以上地区覆盖率分别为97.90%和89.61%,若增加4颗中轨卫星,以15°仰角对我国的覆盖率为99.99%。 相似文献
69.
70.
Cluster analysis in industrial market segmentation through artificial neural network 总被引:6,自引:0,他引:6
Market segmentation has commonly applied cluster analysis. This study intends to make the comparison of conventional two-stage method with proposed two-stage method through the simulated data. The proposed two-stage method is the combination of self-organizing feature maps and K-means method. The simulation results show that the proposed scheme is better than the conventional two-stage method based on the rate of misclassification. 相似文献