全文获取类型
收费全文 | 2962篇 |
免费 | 18篇 |
国内免费 | 2篇 |
专业分类
电工技术 | 5篇 |
综合类 | 1篇 |
化学工业 | 53篇 |
金属工艺 | 12篇 |
机械仪表 | 4篇 |
建筑科学 | 26篇 |
矿业工程 | 5篇 |
能源动力 | 3篇 |
轻工业 | 59篇 |
水利工程 | 6篇 |
石油天然气 | 4篇 |
无线电 | 38篇 |
一般工业技术 | 93篇 |
冶金工业 | 2549篇 |
自动化技术 | 124篇 |
出版年
2022年 | 6篇 |
2020年 | 6篇 |
2019年 | 18篇 |
2018年 | 13篇 |
2017年 | 5篇 |
2016年 | 9篇 |
2015年 | 8篇 |
2014年 | 16篇 |
2013年 | 40篇 |
2012年 | 28篇 |
2011年 | 29篇 |
2010年 | 33篇 |
2009年 | 20篇 |
2008年 | 36篇 |
2007年 | 38篇 |
2006年 | 27篇 |
2005年 | 29篇 |
2004年 | 15篇 |
2003年 | 11篇 |
2002年 | 19篇 |
2001年 | 15篇 |
2000年 | 14篇 |
1999年 | 77篇 |
1998年 | 661篇 |
1997年 | 395篇 |
1996年 | 300篇 |
1995年 | 143篇 |
1994年 | 123篇 |
1993年 | 174篇 |
1992年 | 29篇 |
1991年 | 34篇 |
1990年 | 43篇 |
1989年 | 43篇 |
1988年 | 31篇 |
1987年 | 45篇 |
1986年 | 43篇 |
1985年 | 35篇 |
1984年 | 7篇 |
1983年 | 9篇 |
1982年 | 17篇 |
1981年 | 32篇 |
1980年 | 28篇 |
1979年 | 9篇 |
1978年 | 11篇 |
1977年 | 73篇 |
1976年 | 157篇 |
1975年 | 6篇 |
1974年 | 4篇 |
1973年 | 3篇 |
1971年 | 3篇 |
排序方式: 共有2982条查询结果,搜索用时 15 毫秒
31.
Laura Akers Herbert H Severson Judy A Andrews Edward Lichtenstein 《Nicotine & tobacco research》2007,9(9):907-914
This study assessed the cost-effectiveness of two low-intensity programs for quitting smokeless tobacco, based on results of a randomized trial with 1,069 volunteer participants. Cost data were collected for two levels of intervention: manual only (a self-help manual) and assisted self-help (the manual plus a videotape and two supportive phone calls from tobacco cessation counselors). Incremental cost-effectiveness ratios were calculated for assisted self-help vs. quitting on one's own, using the manual-only quit rate and data from another study as alternative proxies for no intervention. A threshold analysis was conducted to determine the spontaneous quit rate at which the manual-only intervention becomes more cost-effective than assisted self-help. The cost to provide and receive the assisted self-help intervention averaged US $56 per participant vs. $20 for the manual-only intervention (societal perspective, Year 2000 dollars). Estimates for incremental cost per quit for the assisted self-help intervention ranged from $922 to $1,758, depending on the proxy used for no intervention. The manual-only intervention was more cost-effective than assisted self-help if quitting among motivated chewers who do not receive treatment does not exceed 3.4%. Support from a wife or partner added little cost to a quit attempt for male chewers ($3-$4). Providing a manual, video, and brief phone counseling to smokeless tobacco users who want to quit is a reasonable use of health care resources. The self-help quitting guide also may be a cost-effective treatment, but it remains to be demonstrated whether it is more effective than quitting on one's own. 相似文献
32.
Self-help cessation programs for smokeless tobacco users: long-term follow-up of a randomized trial.
Hebert H Severson Judy A Andrews Edward Lichtenstein Brian G Danaher Laura Akers 《Nicotine & tobacco research》2007,9(2):281-289
This paper presents long-term outcomes of the largest clinical trial of smokeless tobacco (SLT) cessation reported to date. SLT users in five northwestern states were recruited to call a toll-free number, and 1,069 users were randomized to one of two self-help conditions: either a manual-only condition or an assisted self-help condition, which included the manual, a targeted video, and two support phone calls. Significant between-group differences were not found for either the 12- or 18-month point-prevalence measure of abstinence from either SLT only or all tobacco products using outcomes based on either the responder or intention-to-treat outcomes. However, using a repeated point-prevalence measure across all three assessment points, we found that significantly more assisted self-help participants reported abstinence, compared with manual-only participants. Compared with manual-only participants, those in the assisted self-help condition were significantly more likely to use recommended cessation techniques. Results demonstrate that low-cost, minimal interventions delivered by mail and phone can help a sizable proportion of individuals quit using SLT. 相似文献
33.
The cytoskeletal components of hamster oocytes, zygotes, and spontaneously activated parthogenotes were examined after immunocytochemical labeling. Microtubules were found only in the anastral, tangentially arranged second meiotic spindle of unfertilized oocytes. Taxol treatment of unfertilized oocytes greatly augmented astral microtubules in both the metaphase II spindle and the cortex. Disruption of the meiotic spindle microtubules with nocodazole resulted in cortical chromosomal scattering. During hamster sperm incorporation and pronuclear formation, no sperm aster was detected in association with the male DNA. Instead, a large overlapping array of microtubules assembled in the cortex. By mitosis, this interphase array disassembled and an anastral metaphase spindle formed. Microtubule and chromatin configurations were also imaged in hamster oocytes injected with human sperm. Astral microtubules were absent from the sperm centrosome. The implications of these results are discussed in relation to the hamster oocyte penetration assay, a test commonly used by in vitro fertilization clinics to demonstrate the fertilizing ability of human sperm. We conclude that since hamsters and humans follow different methods of centrosome inheritance, maternal and paternal, respectively, the hamster may be an inappropriate model for exploring microtubule and centrosomal defects in humans or for assaying postinsemination forms of human male fertility defects. 相似文献
34.
在重点说明影响传输光纤设计的主要问题的同时,简要介绍了各种升级方式所面临的主要技术挑战,并详细说明这些挑战对传输光纤提出的技术要求。 相似文献
35.
Nucleation-limited aggregation in fractal growth 总被引:1,自引:0,他引:1
36.
OBJECTIVE: The authors report the use of multiple implanted intraspinal port and catheter systems per test animal to study the in vivo functional characteristics and reliability of a new implantable spinal drug delivery port system. METHODS: Four ewes were each implanted with two epidural and one subarachnoid silicone elastomer catheters at the lumbar level. Each catheter was connected in series to one of three Therex filtered spinal delivery ports implanted subcutaneously in a similar grid pattern in each ewe to facilitate percutaneous identification. Saline (2 ml) was injected 3 times weekly in each port. The ease of injection and behavioral responses were recorded for 207-213 days of implantation until sacrifice/necropsy. RESULTS: All ports functioned reliably during the study. However, injection through two of the four subarachnoid catheters resulted in behavioral withdrawal responses intermittently. This behavioral pattern was much less common after epidural port injections. All four subarachnoid and four of eight epidural port and catheter systems were tested with local anesthetic just before sacrifice. Motor block was observed in three of four subarachnoid and three of four epidural port and catheter systems tested. Integrity of the other four epidural ports was tested by injection of methylene blue at sacrifice. This dye did not distribute in the epidural space in one of the latter four epidural ports (not local anesthetic tested) because of a concentric fibrotic reaction about the catheter. Similar fibrotic reactions surrounded the catheters that failed a functional test with local anesthetic. CONCLUSIONS: The implantable intraspinal port system tested functions reliably under repetitive percutaneous access. However, filtering such ports, though desirable to prevent entry of debris into the spinal canal, did not eliminate pericatheter chronic subarachnoid and epidural reaction. The number of test animals required to test 12 ports chronically was reduced by two-thirds without undue trauma to the individual test subject. Chronic percutaneous injection of an implanted subarachnoid system is feasible but may be associated with behavioral effects similar to that seen with chronic epidural systems. Fibrosis around chronic silicone catheters limited functional utility in one-fourth of the implanted test systems. Further study of the potential reactivity of chronic epidural and subarachnoid catheters is indicated. 相似文献
37.
RW Sidwell DF Smee RP Warren JH Huffman BJ Gilbert RA Burger FC Pearson 《Canadian Metallurgical Quarterly》1993,20(4):279-292
ImuVert, a sterile preparation composed primarily of Serratia marcescens membrane vesicles and ribosomes, was significantly inhibitory to murine cytomegalovirus (MCMV) infections in BALB/c mice. Antiviral activity was manifested as increased survivor number and decreased recoverable virus titers in spleens, lungs and salivary glands. Treatments were intraperitoneal (i.p.) beginning 24 h pre, 4 h post- or 24 h post-virus inoculation and then repeated 4 days later. Doses of 5, 16 or 50 micrograms/mouse were effective; 160 micrograms/mouse, which caused host weight loss in toxicity controls, was not inhibitory to the infection. A single i.p. treatment of mice substantially augmented natural killer (NK) cell activity and increased total B-cells, while reducing total T- and T-helper cells. A late (48 h) decline in T-cell function and transient increases in B-cell function were observed in the treated animals. Serum interferon was not induced. Mice pretreated with anti-asialo GM1 antibody to reduce their NK cell populations, then infected with MCMV and treated with ImuVert were protected to the same degree as normal animals. Severe combined immunodeficient mice infected with MCMV and treated with ImuVert were not protected from the infection. These data suggest ImuVert to act by a mechanism other than NK cell activation in preventing MCMV infections. 相似文献
38.
A Dick G Adam E Spüntrup A Prescher A Mühler RW Günther 《Canadian Metallurgical Quarterly》1996,165(4):392-397
PURPOSE: In an experimental pyogenic liver abscess model, the signal intensities were compared intraindividually and interindividually after the application of a new blood pool contrast agent, 24-gadolinium-DTPA (diethylenetriamine-pentaacetic acid) cascade polymer, and after the application of gadopentetate dimeglumine. METHODS: In 20 rabbits with experimentally induced liver abscesses, the relative signal intensities of the liver, abscess centre, abscess wall and portal vein were assessed before and between 30 seconds and 60 minutes after injection of a 25 mumol/kg dose of gadolinium polymer and of 100 mumol/kg of gadolinium-DTPA, respectively. Measurements were performed at 1.5 Tesla, using a head coil and a Flash-2-D sequence. RESULTS: The interindividual comparison (unpaired T-test, p < 0.05) yielded significant differences of the relative signal intensities of the abscess centre (at any time point after contrast-media application), abscess wall (between 15 and 60 minutes after contrast media application), and portal vein (between 30 seconds and 7.5 minutes after contrast media application). The interindividual comparison showed a significantly higher abscess centre-liver contrast (between 30 seconds and 12.5 minutes after contrast media application) and a significantly higher abscess wall-centre contrast (between two and 7.5 minutes after contrast media application) after the application of gadolinium polymer compared with gadopentetate dimeglumine. CONCLUSION: In this animal model, the higher abscess centre-liver contrast after the application of gadolinium polymer was the basis for a better and prolonged visibility of the abscesses, as compared with images acquired after injection of gadopentetate dimeglumine. 相似文献
39.
Minor inflammatory changes are often found in tissues of infants who die suddenly. Recently it has been proposed that these infiltrates signal significant underlying infectious disease and are responsible for death. Currently there is no unanimity about the percentage of cases in which inflammatory infiltrates occur and no international consensus in regard to the minimal criteria required for their diagnosis or their significance. We recommend that the presence of minor inflammatory infiltrates should not detract from the diagnosis of sudden infant death syndrome (SIDS) until further study has determined otherwise. 相似文献
40.
Rutherfordα-particles backscattering technique was employed for measurements of diffusion rates in metallic glasses. Effects of relaxation,
crystallization and plastic deformation on diffusion rates were also investigated.
It has been observed that the diffusion rates of a metallic solute are of the same orders of magnitude in both metal-metal
and metal-metalloid glasses. A higher diffusivity is likely if there is a large difference between melting points of the solute
and matrix. Relaxation has no effect on diffusion, however, diffusivity increases on crystallization. An increase in diffusivity
is also observed on plastic deformation of metallic glass. 相似文献