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71.
72.
Colombo P. J.; Rivera D. T.; Martinez J. L. Jr.; Bennett E. L.; Rosenzweig M. R. 《Canadian Metallurgical Quarterly》1997,111(1):114
This study examined effects on memory formation produced by [Leu]enkephalin and [Met]enkephalin administration in 2 regions of the 2-day-old chick brain involved in memory formation: the intermediate medial hyperstriatum ventrale (IMHV) and the lobus parolfactorius (LPO). Basal concentrations of endogenous [Leu]enkephalin and [Met]enkephalin were determined for 5 brain regions, and effects of 1-trial peck-avoidance training on enkephalin concentrations were examined in the IMHV and LPO. [Leu]enkephalin was amnestic when administered in the IMHV but not in the LPO. In contrast, [Met]enkephalin may be amnestic when administered in the LPO but not in the IMHV. Training decreased [Met]enkephalin concentration in the LPO but not in the IMHV. Training had no effect on [Leu]enkephalin concentration in either the IMHV or the LPO. Thus, amnestic effects of [Leu]- or [Met]enkephalin administration are brain-region specific. Regional activity of endogenous [Met]enkephalin during memory formation is consistent with localized amnestic effects produced by [Met]enkephalin administration. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
73.
Will Spaulding; Lynne Rosenzweig; Rand Huntzinger; Rue L Cromwell; David Briggs; Terry Hayes 《Canadian Metallurgical Quarterly》1980,89(5):635
Tested 32 psychiatric inpatients (approximate mean age 23 yrs) with a modification of C. Eriksen and J. Collins's visual pattern integration test (1967). Ss were divided into schizophrenic and nonschizophrenic groups and were compared with 20 hospital staff and 20 college students. The visual pattern integration functions of schizophrenics were found to be different from those of college students, but no other group differences were found. Among the inpatients, no correlations were found between visual pattern integration and premorbid adjustment, symptomatology, or various clinical/demographic factors. The one group difference appears to be the result of variables such as age and task motivation. It is concluded that icon-processing abnormalities, as represented by visual pattern integration deficits, cannot account for posticonic abnormalities found in schizophrenics. (27 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
74.
E. G. Boring, the preeminent historian of experimental psychology, wrote a letter shortly before his death in 1968 concerning G. T. Fechner's first insight into the fundamental principle of psychophysics on October 22, 1850. The celebration of that date at Harvard, more or less annually, and the establishment there of the first chair of psychophysics are recounted in the letter and interwoven with Boring's own birthday (October 23). The letter is published here as a minor contribution to the centennial of Fechner's death (November 18, 1887). That event was scheduled for celebration at Leipzig University by a three-day symposium in June devoted to Fechner's founding of psychophysics and, hence, of experimental psychology. Boring's later skepticism about the validity of certain landmark dates in scientific history was meant to deemphasize the contribution of the individual and to strengthen the role of the impersonal Zeitgeist. But it appears that this skepticism may have arisen, in part, from Boring's recognition of his subjectivity in playfully confounding Fechner's date of insight with his own birthday. Overgeneralization may have followed the fun. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
75.
This paper describes the development of novel particle-based fluorescence resonance energy transfer (FRET) sensors to quantify the concentration and monitor the binding affinity of carbohydrates and glycoproteins to lectins, which are carbohydrate binding proteins. The sensing approach is based on FRET between fluorescein (donor)-labeled lectin molecules, adsorbed on the surface of micrometric polymeric beads, and polymeric dextran molecules labeled with Texas Red (acceptor). The FRET efficiency of the donor-acceptor pair decreases in the presence of carbohydrates or glycoproteins that compete with the Texas Red-labeled dextran molecules on the lectinic binding sites. The inhibitory effect is concentration and time dependent. The sensing technique enables the discrimination between carbohydrates and glycoproteins based on their binding affinity to the FRET sensing particles as well as quantitative analysis of carbohydrates and glycoproteins in aqueous samples. In the future, the newly developed sensors could enable screening glycoprotein-based drugs for their binding affinity toward selective receptors. 相似文献
76.
Ferchmin P. A.; Bennett Edward L.; Rosenzweig Mark R. 《Canadian Metallurgical Quarterly》1975,88(1):360
To test the relative effectiveness of direct vs indirect interaction with an enriched environment, 2 experiments were conducted with Berkeley S1 rats. Some Ss were housed in groups of 12 in large enriched condition (EC) cages while littermate "observer" (OC) Ss were placed singly in small wire-mesh cages within EC. A 3rd group was housed singly in an impoverished condition (IC) where stimulation was minimal. After 30 days, Ss were killed and the brains dissected. In both experiments the usual pattern of EC-IC differences in brain weights appeared, whereas OC showed no significant differences from IC. On measures of exploratory behavior taken during the last 2 days of Exp II, IC fell significantly below EC, and OC was somewhat below IC. Thus EC differed from both IC and OC in brain and in behavior. Active contact with an enriched environment appears necessary for development of EC effects. (35 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
77.
Suggests that the article by J. C. McCullers (see record 1970-10077-001) on G. Stanley Hall's influence is misleading; Hall has not been forgotten. The author comments on Hall's place as a founder and 1st president of the American Psychological Association, on the comparison of W. James with Hall, and notes that it is time that Hall's importance be more fittingly assessed. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
78.
Heat deflection temperature and Vicat softening point of polystyrene and polymethylmethacrylate with various thermal histories were measured. Surface residual stresses were characterized by liquid crazing. Residual stress profiles across the sample thickness were also measured. It is suggested that the softening behavior of glassy polymers is affected by the state of the residual stresses in addition to the traditionally accepted free volume approach. 相似文献
79.
Rosenzweig AC 《Accounts of chemical research》2001,34(2):119-128
Copper is an essential element in all living organisms, serving as a cofactor for many important proteins and enzymes. Metallochaperone proteins deliver copper ions to specific physiological partners by direct protein-protein interactions. The Atx1-like chaperones transfer copper to intracellular copper transporters, and the CCS chaperones shuttle copper to copper,zinc superoxide dismutase. Crystallographic studies of these two copper chaperone families have provided insights into metal binding and target recognition by metallochaperones and have led to detailed molecular models for the copper transfer mechanism. 相似文献
80.
H.B. Parizi L. Rosenzweig J. Mostaghimi S. Chandra T. Coyle H. Salimi L. Pershin A. McDonald C. Moreau 《Journal of Thermal Spray Technology》2007,16(5-6):713-721
This work presents numerical simulation results for molten nickel and zirconia (YZS) droplets impacting on different microscale-patterned
surfaces of silicon. The numerical simulation clearly showed the effect of surface roughness and solidification on the shape
of the final splat, as well as the pore creation beneath the sprayed material. Simulations were performed using computational
fluid dynamic software, SimDrop. The code uses a three-dimensional finite-difference algorithm solving the full Navier-Stokes
equation, including heat transfer and phase change. A volume of fluid (VOF) tracking algorithm is used to track the droplet-free
surface. Thermal contact resistance at the droplet-substrate interface is also included in the model. Specific attention is
paid to the simulation of droplet impact under plasma spraying conditions. Droplet sizes ranged from 15 to 60 microns with
initial velocities of 70-250 m/s. Substrate surfaces were patterned with regular arrays of cubes 1-3 μm high, spaced either
1 μm or 5 μm from each other. Different splat morphologies produced by simulations are compared with those obtained from the
experiment conducted under the same impact and surface conditions.
This article is an invited paper selected from presentations at the 2007 International Thermal Spray Conference and has been
expanded from the original presentation. It is simultaneously published in Global Coating Solutions, Proceedings of the 2007 International Thermal Spray Conference, Beijing, China, May 14-16, 2007, Basil R. Marple, Margaret M. Hyland, Yuk-Chiu Lau, Chang-Jiu Li, Rogerio S. Lima, and Ghislain
Montavon, Ed., ASM International, Materials Park, OH, 2007. 相似文献