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51.
JR Beach JH Dennis AJ Avery CL Bromly RJ Ward EH Walters SC Stenton DJ Hendrick 《Canadian Metallurgical Quarterly》1996,154(5):1394-1400
To clarify whether asthma may be caused by fume from welding mild steel and to evaluate the possible strength of such an effect, we quantified airway responsiveness among young shipyard workers with different levels of fume exposure. Clinical investigation comprised a cross-sectional survey of 19- to 27-yr-old workers who were completing 3 to 9 yr of employment in various trades, and a control group of 15- to 17-yr-old school leavers who were applying for apprenticeships within the same trades. Both groups were subdivided into negligible-, ambient-, or high-exposure subgroups according to expected levels of fume exposure. Actual exposures were assessed in a parallel environmental survey. Participants were investigated by questionnaire, skin prick tests, spirometry, and methacholine tests. Complete data sets were obtained from 1,024 of the 1,070 eligible subjects (96%). Among the workers but not the school leaver controls, there was an increasing prevalence of positive methacholine tests across the exposure subgroups-negligible 37%, ambient 44%, high 49% (p < 0.05). Regression analyses showed that in males after allowing for the effects of atopy, current smoking, and age, the estimated geometric mean level of airway responsiveness of regular welders was twice that of workers with negligible exposure after 5 yr of work. This implies that fume exposure may have been critical in causing asthma in about 1% of the welders. A lesser effect (though not significantly so) was noted among the workers with ambient exposure. 相似文献
52.
An existing computer model capable of predicting the response of three-dimensional semi-rigid steel framed buildings, including continuous floor systems, at elevated temperatures has been extended to include the possibility of extensive strain reversal within the material constitutive relationship. This allows the behaviour in cooling and the effect o f fire spread on steel-framed buildings to be investigated. A number of examples are presented to give an indication of the likely effects of cooling behaviour within the analysis. An initial study has also been made into the structural effects of fire spread from a single ignition point into adjacent bays of a two-dimensional steel building frame. It is shown that some of the distortions caused by the fire are increased by progressive fire spread, as compared with simultaneous burning across the same range of compartments. 相似文献
53.
20 pairs of sera from the National System of Seroepidemiological Surveillance of the triple viral vaccine received in the laboratory with febrile rash diagnosis were studied. By using the hemagglutination inhibition test, it was observed an abnormal answer of antibodies to both rubella and measles through a falling of the antibody titre in one or both diseases, or in one of them with seroconversion to the other one. With the aim of defining the existence of a possible polyclonal activation already described in literature, it was decided to study the antibody response to family Herpesviridae (HSV, EBV, CMV, VZV). 80% of answer to these viruses were found. The results are submitted and discussed. 相似文献
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de Boer K AP Jansen van Santen RA SC Parker 《Canadian Metallurgical Quarterly》1996,53(21):14073-14079
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A study of bubble nucleation in liquid nitrogen and liquid hydrogen has been made in a 120 mm bubble chamber using a high speed cine camera.The initiation and growth of bubbles from artificially prepared cavities was studied. These cavities, produced in both copper and brass surfaces, had mouth radii ranging from 50 μm to 190 μm with depths varying from 110 μm to 500 μm. The liquids were superheated by either heating the surface containing the cavities or by reducing the pressure of the liquid, or by combining both of these methods.The heat fluxes required for initiation of boiling were greater than those required to sustain nucleation from a given site. The growth rate of the bubbles at constant liquid pressure was dependent on a number of factors. It changes as a bubble grew out of the thermal or superheated layer above the metal surface. After an initial period of more rapid growth the vapour volume increased linearly with time. The growth rate was dependent on the liquid used; being slower in liquid hydrogen than in liquid nitrogen. Formulae were obtained which predicted the observed variations in growth rate and departure volume.No nucleation was observed from the test surfaces for a pressure drop alone; the surfaces had to be heated before nucleation would occur. It is thought that this was due to the existence of a zero contact angle for cryogenic liquids on solid surfaces. 相似文献
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LJ Huang FC Chang KH Lee JP Wang CM Teng SC Kuo 《Canadian Metallurgical Quarterly》1998,6(12):2261-2269
2-Amino (6), 2-alkylamino (7-8), 2-methoxy (9), 2-acetamido (10), and 5,8-diacetoxy (11) derivatives of the lead compound 2,3-dichloro-5,8-dimethoxy-1,4-naphthoquinone (4) were synthesized, together with 6,7-dichloro-5,8dimethoxy-1,4-naphthoquinone (5), a positional isomer of 4. Antiplatelet, antiinflammatory, and antiallergic activities were evaluated, and most compounds were quite potent in all assays. Compounds 5 and 9-11 were especially active; however, 5 was ineffective against neutrophil superoxide formation, and 10 was ineffective against mast cell degranulation. 相似文献