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141.
Fourteen women with amenorrhea-galactorrhea were treated with bromo-ergocryptine. Serum prolactin hPRL, hLH, hFSH, estradiol 17-beta (E2), and progesterone values were determined before and during treatment. No consistent pretreatment hormonal pattern was found. During treatment hPRL levels fell in 13 of 14 patients, and E2 rose in 12 of 14 patients. Levels of hLH became normal, and amounts of hFSH did not change. Galactorrhea lessened in all cases and ceased in 11. Menses resumed in 11 patients and 3 women became pregnant. Cessation of galactorrhea and resumption of menses occurred irrespective of initial hPRL or hLH levels. It is suggested that improvement of galactorrhea and resumption of menses in some patients with normal hPRL values are the result of increased serum E2 levels and may be due to a direct action of bromo-ergocryptine on the ovary. Bromo-ergocryptine may also be effective in treatment of amenorrhea, unassociated with galactorrhea or elevated hPRL levels. 相似文献
142.
The first case of the unstable Hb Genova as a result of sporadic mutation is described. It is found in a 3-year-old Canadian boy of East Indian extraction with chronic Heinz body haemolytic anaemia. 相似文献
143.
Fabio Rizzo Francesco Meinardi Riccardo Tubino Roberto Pagliarin Giovanna Dellepiane Antonio Papagni 《Synthetic Metals》2009,159(5-6):356-360
The synthesis of a new DO3A-based macrocyclic ligand bearing a 8-hydroxyquinoline residue together with the preparation of its Eu3+ and Er3+ neutral complexes are described. In a previous report [F. Rizzo, A. Papagni, F. Meinardi, R. Tubino, M. Ottonelli, G.F. Musso, G. Dellepiane, Synth. Met. 147 (2004) 143], we have shown that lanthanide complexes display very high stability combined with a good luminescence in aqueous solution under UV radiation, which indicate an energy transfer process from the excited 8-hydroxyquinoline moiety to the metal. In this work, we correlate the ability to transfer the energy from the sensitizer to lanthanide ion with pH behaviour of the antenna. Furthermore, the variation of pH in Eu3+ complex supports the hypothesis of presence of charge-transfer transitions. The good solubility and sensitized emission in different solvents (organic and water) are very important aspects for their technologic applications as luminescent probes or NIR-emitting devices. 相似文献
144.
SC McClinsey 《Canadian Metallurgical Quarterly》1999,34(1):213-225
HIV seroconversion as a result of an occupational exposure is a terrifying concern of healthcare workers who deliver care to patients in a variety of health care settings. In this article the most recent CDC guidelines for the management of HIV exposure and postexposure prophylaxis are reviewed. Prevention of bloodborne pathogen exposures, specifically through the selection of safety devices, is recognized as an important issue. 相似文献
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Mapping single atoms in biological structures is now becoming within the reach of analytical electron microscopy. Electron energy-loss spectroscopy (EELS) in the field-emission scanning transmission electron microscope (STEM) provides a particularly high sensitivity for detecting the biologically important element, phosphorus. Imaging can be performed at low dose with dark-field STEM prior to analysis at high dose, so that structures of macromolecular assemblies can be correlated with the numbers of specific atoms that they contain. Measurements confirm theoretical predictions that single atom detection requires a nanometer-sized probe. Although phosphorus atoms may have moved several nanometers from their original positions by beam-induced structural degradation at the high required dose of approximately 10(9) e/nm2, damaged molecules are nevertheless stable enough to be analyzed at 1 or 2 nm resolution. Such analyses can only be achieved by means of spectrum-imaging with correction for specimen drift. Optimal strategies for mapping small numbers of phosphorus atoms have been investigated using well-characterized specimens of DNA plasmids and tobacco mosaic virus. 相似文献
147.
Crippa C. Nicollini G. Mecchia A. Rizzo P. Confalonieri P. Pernici S. Nagari A. Viani E. Bietti I. Adduci F. Mariani S. Calloni A. Moioli M. Mandelli S. Dallavalle C. 《Solid-State Circuits, IEEE Journal of》1999,34(2):170-181
A low-voltage, low-power CMOS single-chip baseband processor for CT2 and CT2+ cordless telephones is presented. The chip integrates a complete voiceband codec, a tone generator, a G721 adaptive differential pulse code modulation coder/decoder, a burst-mode logic controller for CT2/CT2+ framings, and an I/Q baseband signal generator. The only external components are made of two quartz crystals. The chip is interfaced with standard microcontrollers through a parallel interface. With a 2.7 V minimum supply, it consumes normal and standby powers of 35 mW and 25 μW, respectively. Maximum supply is 5.5 V, and temperature range is from -40 to 70°C. Chip area (including scribe line) is 55.5 mm2 in a 0.8 μm N-well double-metal single-poly CMOS process with implanted capacitors 相似文献
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