全文获取类型
收费全文 | 2192篇 |
免费 | 18篇 |
国内免费 | 3篇 |
专业分类
电工技术 | 3篇 |
综合类 | 3篇 |
化学工业 | 31篇 |
金属工艺 | 5篇 |
机械仪表 | 5篇 |
建筑科学 | 23篇 |
矿业工程 | 1篇 |
能源动力 | 3篇 |
轻工业 | 12篇 |
水利工程 | 13篇 |
石油天然气 | 6篇 |
无线电 | 19篇 |
一般工业技术 | 76篇 |
冶金工业 | 1987篇 |
原子能技术 | 1篇 |
自动化技术 | 25篇 |
出版年
2020年 | 2篇 |
2018年 | 4篇 |
2017年 | 2篇 |
2016年 | 9篇 |
2015年 | 8篇 |
2014年 | 5篇 |
2013年 | 9篇 |
2012年 | 6篇 |
2011年 | 8篇 |
2010年 | 15篇 |
2009年 | 7篇 |
2008年 | 9篇 |
2007年 | 11篇 |
2006年 | 11篇 |
2005年 | 13篇 |
2004年 | 14篇 |
2003年 | 18篇 |
2002年 | 7篇 |
2001年 | 9篇 |
2000年 | 9篇 |
1999年 | 62篇 |
1998年 | 686篇 |
1997年 | 315篇 |
1996年 | 237篇 |
1995年 | 116篇 |
1994年 | 101篇 |
1993年 | 126篇 |
1992年 | 14篇 |
1991年 | 28篇 |
1990年 | 32篇 |
1989年 | 32篇 |
1988年 | 37篇 |
1987年 | 31篇 |
1986年 | 16篇 |
1985年 | 17篇 |
1984年 | 2篇 |
1983年 | 4篇 |
1982年 | 5篇 |
1981年 | 12篇 |
1980年 | 14篇 |
1978年 | 3篇 |
1977年 | 27篇 |
1976年 | 106篇 |
1973年 | 2篇 |
1972年 | 2篇 |
1970年 | 1篇 |
1969年 | 2篇 |
1962年 | 1篇 |
1956年 | 1篇 |
1955年 | 1篇 |
排序方式: 共有2213条查询结果,搜索用时 203 毫秒
61.
The Surveillance Research Program of the American Cancer Society's Department of Epidemiology and Surveillance reports its 32nd annual compilation of cancer incidence, mortality, and survival data for the United States and around the world. 相似文献
62.
BACKGROUND: Hepatocellular carcinoma (HCC) over 10 cm in diameter at the time of diagnosis continues to account for a number of patients undergoing hepatic resection. This study evaluated the clinicopathological features and outcome following surgery for large HCC. METHODS: Forty patients with a large HCC (greater than 10 cm) (group 1) resected between 1991 and 1996 were studied retrospectively. They were compared with 245 patients who had smaller HCCs (10 cm or less) (group 2). RESULTS: No patient in group 1 had hepatitis C infection compared with 22.9 per cent in group 2 (P=0.001). Patients in group 1 were significantly younger, had higher alpha-fetoprotein levels (16750 versus 1864 ng/ml; P < 0.001), better liver function, a higher incidence of multiple tumours (27 of 40 versus 42.0 per cent; P=0.003) and venous invasion (35 of 40 versus 52.2 per cent; P < 0.001), and underwent more major resections (37 of 40 versus 26.5 per cent; P < 0.001) than those in group 2. Morbidity and mortality rates and hospital stay were comparable in the two groups. For group 1, the 1-, 3- and 5-year disease-free survival rates were 42, 30 and 28 per cent respectively. Multiple tumours, venous invasion and impaired liver function were factors associated with recurrence. CONCLUSION: Large HCC had specific clinicopathological features. In selected patients, resection is safe and offers the chance of long-term disease-free survival. 相似文献
63.
WJ Cho EK Kim MJ Park SU Choi CO Lee SH Cheon BG Choi BH Chung 《Canadian Metallurgical Quarterly》1998,6(12):2449-2458
In this study a series of 3-arylisoquinoline derivatives were synthesized and cytotoxicity against human melanoma tumor cell evaluated, and a three dimensional quantitative structure-activity relationship was investigated using the comparative molecular field analysis (CoMFA). The results suggested that the electrostatic, steric and hydrophobic factors of 3-arylisoquinolines were strongly correlated with the antitumor activity. Considerable predictive ability (cross-validated r2 as high as 0.721) was obtained through CoMFA. 相似文献
64.
This report describes a simple, rapid, automated microassay for measuring in vitro changes of oxidative burst of phagocytes following challenge with metals for orthopedic devices. The production of reactive oxygen species (ROS) by polymorphonuclear leukocytes (PMNs) was measured using 2',7'-dichlorofluorescin-diacetate (DCFH-DA) as fluorescent probe. DCFH-DA enters the cells and is oxidized by ROS to fluorescent DCF. The DCF generated was directly proportional to ROS produced intracellularly: The fluorescence intensity was read and converted to an index of ROS production by cells. In our experimental system, granulocytes (PMNs) were isolated from normal human blood and seeded in microplates. To verify if metals could influence ROS production, chromium, cobalt, nickel, molybdenum, titanium, aluminum, and vanadium prepared as aqueous extracts in phosphate-buffered saline were tested onto PMNs using phorbolmyristate acetate (PMA) as positive control. Molybdenum, aluminum, and vanadium increased ROS generation by PMNs, while signals not different from unstimulated PMNs were recorded for chromium, cobalt, nickel, and titanium. The DCFH-DA microplate-based assay provides an in vitro tool for the detection of oxygen-reactive species generated by PMNs as a response to metals. 相似文献
65.
66.
Scanning with Tc-99m labeled RBC was performed in two patients with recurrent postoperative gastrointestinal bleeding after partial colonic resection. Imaging correctly identified the source of bleeding at the anastomotic site in the large bowel, effectively contributing in the patient's treatment planning. Radionuclide scintigraphy provides a simple, noninvasive modality to diagnose and manage difficult clinical situations such as postoperative bleeding. 相似文献
67.
SC Shim DH Yoo JK Lee HK Koh SR Lee SH Oh SY Kim 《Canadian Metallurgical Quarterly》1998,25(12):2464-2468
Ankylosing spondylitis (AS) results in disease-specific inflammation at the site of ligamentous insertion into the bone. Atlantoaxial joint subluxation and vertical subluxation of the axis may occur as a consequence of instability resulting from the inflammatory process. Spontaneous anterior atlantoaxial subluxation is a well recognized complication in about 2% of patients with AS, and presents with or without signs of spinal cord compression. Vertical subluxation may follow anterior or posterior subluxation. It was noted in 3-8% of patients with rheumatoid arthritis, but is an exceedingly rare complication of AS. Moreover, it has never been reported that multiple cerebellar infarction and bulbar symptoms developed spontaneously due to atlanto-occipital subluxation and vertical subluxation in a patient with a long [corrected] history of AS. We describe a man with AS who developed multiple cerebellar infarction due to vertebral artery obstruction and bulbar symptoms associated with atlanto-occipital subluxation and vertical subluxation. 相似文献
68.
AI Robles ML Rodriguez-Puebla AB Glick C Trempus L Hansen P Sicinski RW Tennant RA Weinberg SH Yuspa CJ Conti 《Canadian Metallurgical Quarterly》1998,12(16):2469-2474
Cyclin D1 is part of a cell cycle control node consistently deregulated in most human cancers. However, studies with cyclin D1-null mice indicate that it is dispensable for normal mouse development as well as cell growth in culture. Here, we provide evidence that ras-mediated tumorigenesis depends on signaling pathways that act preferentially through cyclin D1. Cyclin D1 expression and the activity of its associated kinase are up-regulated in keratinocytes in response to oncogenic ras. Furthermore, cyclin D1 deficiency results in up to an 80% decrease in the development of squamous tumors generated through either grafting of retroviral ras-transduced keratinocytes, phorbol ester treatment of ras transgenic mice, or two-stage carcinogenesis. 相似文献
69.
B Weisser S Grüne R Burger H Blickenstorfer J Iseli SH Michelsen R Opravil S Rageth ER Sturzenegger P Walker 《Canadian Metallurgical Quarterly》1994,8(4):227-231
In a retrospective study of 50 consecutive children with posterior fossa tumors treated at Texas Children's Hospital, Houston, Tex., in 1989-1992, we evaluated perioperative factors which might influence the development of postoperative cerebrospinal fluid leaks. Factors analyzed included the presence of preoperative hydrocephalus, the institution of cerebrospinal fluid diversion, and the method of dural closure. No statistically significant impact on subsequent cerebrospinal fluid leakage was demonstrated. 相似文献
70.
The effects of different writing and reading temperatures on the switching voltage waveform, permeability, and flux state of standard nickel-copper-manganese and copper-manganese ferrite memory cores have been investigated over a temperature range of 0 to 70°C. These temperatures are well below the Curie temperatures of the materials being tested. It has been found that writing at a higher temperature than the read temperature leads to increased low temperature voltage switching thresholds, higher low frequency (<40 MHz) permeabilities, lower high frequency (>40 MHz) permeabilities, and flux states almost equal to the equilibrium value for the lower temperature. Read current pulse rise time and duration have been found to have no effect on the increase in threshold with temperature. Externally produced stresses have been used to simulate the effects of temperature changes on the core. 相似文献