基于线性衰减的用户兴趣建模①

针对电子商务参与者兴趣变化异常频繁的特点,提出了基于线性衰减的用户兴趣模型。根据初始注册信息和浏览行为构建了链式用户偏好表,所有用户的偏好链表组成用户兴趣模型。兴趣模型中的用户偏好值在固定时间间隔t进行线性衰减直至变为0而被淘汰。若在衰减过程中产生了用户对某项目新的评分,该项目兴趣模型中的偏好值将被更新为此评分。实验证明,基于线性衰减的用户兴趣建模方法是有效的。     

改进的排队系统三阶段法及其仿真

通过对M/M/C/N/∞排队模型下机场排队场景的分析,提出运用三阶段法仿真策略设计仿真系统时,用于处理由于附加条件限制使B类事件变为C类事件的规则,同时对已有的三阶段仿真流程进行改进,使三阶段法仿真描述更加清晰,设计更容易。利用C#.NET和LINQ（Language IntegratedQuery）语言实现该三阶段法排队仿真系统,将TPA排队仿真系统中参数设置成track≥1,queue≥1,就可以输出任何M/M/C/N/∞排队系统的仿真结果,最后对仿真结果进行简单的分析。     

一种新型正交导频在信道估计中的应用研究

关于无线通信问题,信道估计技术属于多输入多输出正交频分复用(MIMO-OFDM)系统.信道估计的准确与否直接关系到MIMO-OFDM系统的误比特率的高低.目前基于导频的信道估计所使用的导频序列抗多径性能较差,影响了信道估计的精度.为了提高估计精度和准确的信道传输特征,采用一种新型正交导频,即与m序列相乘的Walsh码作为导频符号插入.新的正交导频具有良好的自相关性和互相关性,可以有效提高系统的抗多径能力.仿真结果表明,新方法是与m序列相乘的Walsh码的信道估计算法,有效降低了系统误比特率,增强了系统的抗多径性能.     

Collapse-free thermal bonding technique for large area microchambers in plastic lab-on-a-chip applications

Bonding is an essential step to form microchannels or microchambers in lab-on-a-chip applications. In this paper, we present a novel plastic thermal bonding technique to seal and form large area microchambers (planar characteristic width and length on the order of 1 mm and characteristic thickness on the order of 10–100 μm) without collapse by introducing a holed pressure equalizing plate (HPEP) that includes holes of the same size and shape as the microchambers. To demonstrate the proposed technique, two types of large area microchambers [(1) 20 × 10 mm and 40 μm thick and (2) 12 × 2.5 mm and 120 μm thick] with microchannels were designed and replicated on plastic substrates by means of hot embossing and injection molding processes with prepared two nickel mold inserts. The replicated large area microchambers as well as the microchannels in the plastic lab-on-a-chip were successfully sealed (i.e., no leakage) and formed without any collapse by the proposed thermal bonding technique with the help of the HPEP.     

基于ArcGIS的公路边坡稳定性评价系统设计与开发

公路边坡稳定性评价是山区高等级公路建设的一项基本工作与重要内容.作者在分析总结当前基于GIS平台的边坡稳定性评价系统研发现状的基础上,以AreGIS为二次开发平台,建立公路边坡稳定性评价系统.系统具有边坡数据管理、边坡稳定性评价、边坡三维地形建立与分析等功能.最后,通过一个实例对系统进行了从数据管理、边坡稳定性评价到三维地形显示等一系列操作的应用测试.     

合成孔径雷达1553B通信接口设计与实现

介绍某型号合成孔径雷达系统的1553B总线通信接口设计方案与工程实现;方案采用国内自主研发的4M/s速率1553B总线接口芯片,PC/104工控机与FPGA结合,通过硬件系统设计和软件编程,实现对1553B总线数据收发和雷达部分辅助数据的提供,实现项目总体对1553B总线通信接口的要求。实际应用情况表明,该通信接口运行稳定、可靠,具有一定的实用性和良好的应用前景。     

Robust DOA estimation and target docking for mobile robots

Direction of arrival (DOA) guided automated target acquisition and docking system is proposed for mobile robots employing the dual-directional antenna system. The dual-directional antenna estimates the DOA of the signal of interest using the ratio of the signal strengths between two adjacent antennas. In practice, DOA estimation poses a significant technical challenge, since the RF signal is easily distorted by the environmental conditions. Therefore, the robot often loses its way in an electromagnetically disturbed environment. To cope with this problem, a robust DOA estimation algorithm is developed based on Kalman filtering. This algorithm allows the robot to reduce the potential error in the estimated DOA, and adjust the robot’s heading to the target transponder without needing to know the positions of current and previous measurements in a global coordinate system. The simulation and experiment results clearly demonstrate that the mobile robot equipped with the developed system is able to dock to a target transponder in an indoor environment partially occupied by obstacles.     

Primary focal segmental glomerulosclerosis: clinical course and response to therapy

Primary focal segmental glomerulosclerosis (FSGS) is a lesion associated with a poor prognosis and results in end-stage renal disease after 5 to 10 years. Based on past experience, many nephrologists have considered primary FSGS a lesion that is steroid resistant and therefore are reluctant to offer steroids as treatment. Recent data, however, have demonstrated that patients with primary FSGS have a response to steroid therapy that is considerably better than had been described. Thus, it may be that nephrologists have been more "steroid reluctant" than the lesion is steroid resistant. To better understand this issue we review the clinical course and response to therapy in patients with primary FSGS.     

Disruption of epithelial cell-matrix interactions induces apoptosis

Cell-matrix interactions have major effects upon phenotypic features such as gene regulation, cytoskeletal structure, differentiation, and aspects of cell growth control. Programmed cell death (apoptosis) is crucial for maintaining appropriate cell number and tissue organization. It was therefore of interest to determine whether cell-matrix interactions affect apoptosis. The present report demonstrates that apoptosis was induced by disruption of the interactions between normal epithelial cells and extracellular matrix. We have termed this phenomenon "anoikis." Overexpression of bcl-2 protected cells against anoikis. Cellular sensitivity to anoikis was apparently regulated: (a) anoikis did not occur in normal fibroblasts; (b) it was abrogated in epithelial cells by transformation with v-Ha-ras, v-src, or treatment with phorbol ester; (c) sensitivity to anoikis was conferred upon HT1080 cells or v-Ha-ras-transformed MDCK cells by reverse-transformation with adenovirus E1a; (d) anoikis in MDCK cells was alleviated by the motility factor, scatter factor. The results suggest that the circumvention of anoikis accompanies the acquisition of anchorage independence or cell motility.     

Transfer of loads between lumbar tissues during the flexion-relaxation phenomenon

STUDY DESIGN AND METHODS: This study used an anatomically detailed model of the lumbar tissues, driven from biologic signals of vertebral displacement and myoelectric signals, to estimate individual muscle and passive tissue force-time histories during the performance of the "flexion-relaxation" maneuver. Eight male university students performed three trials each of the "flexion-relaxation" maneuver with six pairs of surface myoelectric electrodes monitoring the right side of the trunk musculature, an electromagnetic device to record lumbar flexion, and videotape to record body segment displacement. OBJECTIVES: To examine the loads on individual tissues during the transfer of moment support responsibility from predominantly active muscle to predominantly passive tissue. SUMMARY OF BACKGROUND DATA: No previous studies, to the authors' knowledge, have examined individual tissue loading during the flexion-relaxation maneuver. RESULTS: Although most subjects were able to "relax" their lumbar extensors in full flexion, activity remained in the thoracic extensors and abdominals. Tissue load predictions suggested that while the lumbar extensor muscles were neurally "relaxed" (i.e., myoelectric silence), substantial elastic forces would assist the passive tissues in extensor moment support. On average, subjects sustained almost 3 kN in compressive load on the lumbar spine and about 755 N of anterior shear during full flexion with only 8 kg held in the hands. CONCLUSIONS: The "relaxation" of lumbar extensor muscles appeared to occur only in an electrical sense because they generated substantial force elastically through stretching. Loading of the interspinous and supraspinous ligaments, in particular, was high relative to their failure tolerance.