Application profile for ISDN

The authors examine some key data processing applications to be used in conjunction with the voice and facsimile services as a platform for deploying ISDN (integrated services digital network) in North America. Special emphasis is placed on the emerging standards of both Accredited Standards Committees (ACS) T1 and X3 in an attempt to harmonize the computer and telecommunication industries towards providing the user with an integrated platform that is vendor-transparent and ubiquitous. This generic platform, which spans a large spectrum of businesses, is presented as a base context for defining user-specific needs and incubating the applications that directly relate to businesses. Distributed transaction processing, electronic data interchange, information retrieval, electronic mail, and file transfer together with seven supplementary services for voice and G4 facsimile are proposed for ISDN deployment in the marketplace. The authors describe how the relevant standards may be exercised through the various ISDN channels and emphasize the value of the North American ISDN User's Forum for commercializing this platform     

Deuterated liquid scintillator (NE230) as a fast neutron detectorfor cold-fusion and other research

Deuterated scintillators (NE230) can provide, without time-of-flight, usable neutron energy spectra for neutrons E _n⩾1 MeV. The authors have assembled and calibrated several of these detectors and used them in experiments searching for d+d fusion-neutron emission (E_n, 2.5 MeV) in Pd+D ₂O electrolysis and Ti+D₂ adsorption at LN temperatures. The detectors yielded direct fusion-neutron spectra and set limits in the Pd+D and Ti+D experiments of <7×10^-24 fusion n/s/dd pair and <3×10^-24 fusion n/s/dd pair respectively. In addition, these detectors have been used for in-beam accelerator experiments requiring coincidence between fast neutrons and scattered ions     

Pressurized fluidized-bed hydro retort ing of raw and beneficiated Eastern oil shales

Bench-scale tests were conducted with raw and beneficiated shales in an advanced multi-purpose research reactor. Raw Alabama shale and raw and beneficiated Indiana shales were retorted at 515 °C using hydrogen pressures of 4 and 7 MPa. Shale feed rates were 15 to 34 kg h⁻¹. High oil yields and carbon conversions were achieved in all tests. Oil yield from Alabama shale hydroretorted at 7 MPa was 200% of Fischer assay. Raw and beneficiated Indiana shales hydroretorted at 7 MPa produced oil yields of 170 and 195% of Fischer assay respectively. Total carbon conversions were >70% for all tests conducted at 7 MPa.     

Jitter in ATM networks and its impact on peak rate enforcement

Cells arriving to an ATM network experience random delays due to queueing in upstream multiplexing stages, notably in customer premises. This is the phenomenon of jitter and the aim of the present paper is to study its influence on peak rate enforcement. We first introduce some general characterizations of jitter and then, describe two models of jittered flows based on simple queueing systems. We discuss the objectives of peak rate enforcement and study the impact of jitter on the dimensioning of jumping window and leaky bucket mechanisms. A useful synthetic characterization of jitter appears to be a remote quantile of the cell delay distribution expressed in units of the initial inter-cell interval.     

Using fractal structure to describe nickel crystal morphology

The morphology of nickel crystals can be quantified using measurements of fractal structure. In the study described in this article, fractal dimensions of cross sections of 16 nickel samples were determined, and the numerical analysis indicates that the more rugged surfaces are characterized by higher fractal dimensions although the relationship between morphology and fractal dimension is relatively weak. However, the data also show that fractal dimension is a better predictor of morphology than apparent density, which is the measurement currently used. The nickel samples were also subjected to an avalanching disc technique that has the potential to separate out the differences in flow in the different types of nickel powder. The differences in flow between powders were ascribed to the similar gross morphologies of the particles, and the presence of shattered individual particles in the mix. For more information, contact A.E. Lewis, University of Cape Town, Precipitation and Crystallisation Research Facility, Department of Chemical Engineering, Rondebosch, 7701, South Africa; +27-21-650-4091; fax +27-21-689-7479; e-mail alison@chemeng.uct.ac.za.     

Reliability evaluation and optimisation of imperfect inspections for a component with multi-defects

In this paper, a model is developed to evaluate the reliability and optimise the inspection schedule for a multi-defect component. The model uses a non-homogeneous Poisson process (NHPP) method in conjunction with a delay time approach. The inspections are designed to detect any defects in the component, however it can be imperfect. The defect is a definable state before a functional failure happens to the component. Occurrences of defects are assumed to follow an NHPP and a defect will be minimally repaired if it is identified during an inspection. It is shown that the failures occurring in an interval of inspection will also follow an NHPP. The situation of imperfect inspections and non-constant inspection intervals are considered. An algorithm is presented to optimise the intervals of inspections in order to maximise the reliability of the component, and the properties of the algorithm are shown. A numerical example with parametric study is given to show the performance of the model and the algorithm.     

The development of adaptive body reactions after intensive physical loading]

The dependence between the activity parameters of muscarine antagonists in the prevention of haloperidol catalepsy in rats and those in tests characterizing the interaction of ligands and various subtypes of m-cholinoceptors was studied. It was established by constructing the mathematical dependence that blockade of m1-cholinoceptors increases, while that of m2-cholinoceptors reduces the antiparkinsonian activity of the drugs. The activity of the muscarine antagonist pentiphan in the prevention of haloperidol-induced catalepsy in rats exceeds the activity of such traditional antiparkinsonian drugs as cyclodol and amedin.     

Novel sulfated oligosaccharides containing 3-O-sulfated glucuronic acid from king crab cartilage chondroitin sulfate K. Unexpected degradation by chondroitinase ABC

We prepared a series of oligosaccharides from king crab cartilage chondroitin sulfate K after exhaustive digestion with testicular hyaluronidase, and determined the structures of four tetrasaccharides and a pentasaccharide by fast atom bombardment mass spectrometry, high performance liquid chromatography analysis of chondroitinase AC-II digests, and 500-MHz 1H NMR spectroscopy. The tetrasaccharides shared the common core structure GlcAbeta1-3GalNAcbeta1-4GlcAbeta1-3GalNAc with various sulfation profiles. One structure was GlcAbeta1-3GalNAc(4S)beta1-4GlcAbeta1-3GalNAc(4S), whereas three of them have the following hitherto unreported structures including a novel glucuronate 3-O-sulfate: GlcA(3S)beta1-3GalNAc(4S)beta1-4GlcAbeta1-3GalNAc(4S), GlcAbeta1-3GalNAc(4S)beta1-4GlcA(3S)beta1-3GalNAc(4S), and GlcA(3S)beta1-3GalNAc(4S)beta1-4GlcA(3S)beta1-3GalNAc(4S), where 3S or 4S represents 3-O- or 4-O-sulfate, respectively. The structure of the pentasaccharide was determined as GlcA(3S)beta1-3GalNAc(4S)beta1-4GlcA(3S)beta1- 3GalNAc(4S)beta1-4GlcA. Chondroitinase ABC digestion of the tetrasaccharides with GlcA(3S) at the internal position destroyed the disaccharide unit containing GlcA(3S) derived from the reducing side and resulted in only the disaccharide unit from the non-reducing side. In contrast, these tetrasaccharides remained totally resistant to chondroitinase AC-II. The results indicated that it is necessary to reevaluate the disaccharide composition of chondroitin sulfate poly- or oligosaccharides purified from various biological sources, since they were usually determined after chondroitinase ABC digestion. It is probable that the structures containing GlcA(3S) would not have been detected.     

Tuberculous meningitis: a 30-year review

Tuberculous meningitis remains an important illness that can be difficult to diagnose in a timely fashion and carries significant morbidity. We present a retrospective review of the cases of tuberculous meningitis diagnosed and treated at a single institution. Fifty-eight cases were identified and stratified according to stage of disease at presentation. Four patients (7%) died; three (5%) developed severe neurological sequelae. Poor outcomes were largely confined to cases presenting in an advanced stage and at the extremes of age. Corticosteroids were administered to 56 patients and may have contributed to the comparatively good outcome in these cases.